| Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 927 | 2021 |
| Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections S Wagner, R Sommer, S Hinsberger, C Lu, RW Hartmann, M Empting, ... Journal of medicinal chemistry 59 (13), 5929-5969, 2016 | 297 | 2016 |
| Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa R Sommer, S Wagner, K Rox, A Varrot, D Hauck, EC Wamhoff, ... Journal of the American Chemical Society 140 (7), 2537-2545, 2018 | 137 | 2018 |
| A safe and convenient method for the preparation of triflyl azide, and its use in diazo transfer reactions to primary amines A Titz, Z Radic, O Schwardt, B Ernst Tetrahedron letters 47 (14), 2383-2385, 2006 | 124 | 2006 |
| Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2 A Butschi, A Titz, MA Wälti, V Olieric, K Paschinger, K Nöbauer, X Guo, ... PLoS pathogens 6 (1), e1000717, 2010 | 117 | 2010 |
| Discovery of Two Classes of Potent Glycomimetic Inhibitors of Pseudomonas aeruginosa LecB with Distinct Binding Modes D Hauck, I Joachim, B Frommeyer, A Varrot, B Philipp, HM Möller, ... ACS chemical biology 8 (8), 1775-1784, 2013 | 112 | 2013 |
| Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections MB Calvert, VR Jumde, A Titz Beilstein journal of organic chemistry 14 (1), 2607-2617, 2018 | 100 | 2018 |
| Methylated glycans as conserved targets of animal and fungal innate defense T Wohlschlager, A Butschi, P Grassi, G Sutov, R Gauss, D Hauck, ... Proceedings of the National Academy of Sciences 111 (27), E2787-E2796, 2014 | 98 | 2014 |
| Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis A Torge, S Wagner, PS Chaves, EG Oliveira, SS Guterres, AR Pohlmann, ... International journal of pharmaceutics 527 (1-2), 92-102, 2017 | 83 | 2017 |
| Covalent lectin inhibition and application in bacterial biofilm imaging S Wagner, D Hauck, M Hoffmann, R Sommer, I Joachim, R Müller, ... Angewandte Chemie International Edition 56 (52), 16559-16564, 2017 | 81 | 2017 |
| Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure–Activity Relationship Study of C-Glycosidic LecB Inhibitors R Sommer, K Rox, S Wagner, D Hauck, SS Henrikus, S Newsad, T Arnold, ... Journal of medicinal chemistry 62 (20), 9201-9216, 2019 | 67 | 2019 |
| The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery R Sommer, S Wagner, A Varrot, C Nycholat, A Khaledi, S Häussler, ... Chemical Science, 2016 | 66 | 2016 |
| Glycomimetics for the inhibition and modulation of lectins S Leusmann, P Ménová, E Shanin, A Titz, C Rademacher Chemical Society Reviews 52 (11), 3663-3740, 2023 | 62 | 2023 |
| Parasite glycobiology: a bittersweet symphony JA Rodrigues, A Acosta-Serrano, M Aebi, MAJ Ferguson, FH Routier, ... PLoS pathogens 11 (11), e1005169, 2015 | 61 | 2015 |
| Lectin antagonists in infection, immunity, and inflammation J Meiers, E Siebs, E Zahorska, A Titz Current Opinion in Chemical Biology 53, 51-67, 2019 | 60 | 2019 |
| Molecular Basis for Galactosylation of Core Fucose Residues in Invertebrates A Titz, A Butschi, B Henrissat, YY Fan, T Hennet, E Razzazi-Fazeli, ... Journal of Biological Chemistry 284 (52), 36223-36233, 2009 | 58 | 2009 |
| Tackling the outer membrane: facilitating compound entry into Gram-negative bacterial pathogens D Saxena, R Maitra, R Bormon, M Czekanska, J Meiers, A Titz, S Verma, ... npj Antimicrobials and Resistance 1 (1), 17, 2023 | 56 | 2023 |
| Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa I Joachim, S Rikker, D Hauck, D Ponader, S Boden, R Sommer, ... Organic & Biomolecular Chemistry 14 (33), 7933-7948, 2016 | 55 | 2016 |
| Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa R Sommer, D Hauck, A Varrot, S Wagner, A Audfray, A Prestel, HM Möller, ... ChemistryOpen 4 (6), 756-767, 2015 | 51 | 2015 |
| Electrochemical synthesis of dimerizing and nondimerizing orthoquinone monoketals D Deffieux, I Fabre, A Titz, JM Léger, S Quideau The Journal of Organic Chemistry 69 (25), 8731-8738, 2004 | 48 | 2004 |
Anne ImbertyCNRSVerified email at cermav.cnrs.fr
