Folgen
Ioannis N Melas
Ioannis N Melas
ARM Ltd, senior data scientist
Bestätigte E-Mail-Adresse bei arm.com
Titel
Zitiert von
Zitiert von
Jahr
Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data
A Mitsos, IN Melas, P Siminelakis, AD Chairakaki, J Saez-Rodriguez, ...
PLoS computational biology 5 (12), e1000591, 2009
1442009
Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data
A Mitsos, IN Melas, P Siminelakis, AD Chairakaki, J Saez-Rodriguez, ...
PLoS computational biology 5 (12), e1000591, 2009
1442009
Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury
IN Melas, T Sakellaropoulos, F Iorio, LG Alexopoulos, WY Loh, ...
Integrative Biology 7 (8), 904-920, 2015
452015
Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs
IN Melas, R Samaga, LG Alexopoulos, S Klamt
PLoS computational biology 9 (9), e1003204, 2013
442013
The species translation challenge—a systems biology perspective on human and rat bronchial epithelial cells
C Poussin, C Mathis, LG Alexopoulos, DE Messinis, RHJ Dulize, ...
Scientific Data 1 (1), 1-14, 2014
422014
Phosphoproteomics in drug discovery
MK Morris, A Chi, IN Melas, LG Alexopoulos
Drug discovery today 19 (4), 425-432, 2014
362014
Modeling of signaling pathways in chondrocytes based on phosphoproteomic and cytokine release data
IN Melas, AD Chairakaki, EI Chatzopoulou, DE Messinis, T Katopodi, ...
Osteoarthritis and Cartilage 22 (3), 509-518, 2014
362014
Combined logical and data-driven models for linking signalling pathways to cellular response
IN Melas, A Mitsos, DE Messinis, TS Weiss, LG Alexopoulos
BMC systems biology 5 (1), 1-12, 2011
312011
Signaling networks in MS: a systems-based approach to developing new pharmacological therapies
E Kotelnikova, M Bernardo-Faura, G Silberberg, NA Kiani, D Messinis, ...
Multiple Sclerosis Journal 21 (2), 138-146, 2015
232015
Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways
A Mitsos, IN Melas, MK Morris, J Saez-Rodriguez, DA Lauffenburger, ...
PLoS One 7 (11), e50085, 2012
202012
Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data
IN Melas, A Mitsos, DE Messinis, TS Weiss, JS Rodriguez, ...
Molecular Biosystems 8 (5), 1571-1584, 2012
162012
Construction of Cell Type-Specific Logic Models of Signaling Networks Using CellNOpt
MK Morris, I Melas, J Saez-Rodriguez
Computational Toxicology, 179-214, 2013
132013
Translational systems pharmacology‐based predictive assessment of drug‐induced cardiomyopathy
DE Messinis, IN Melas, J Hur, N Varshney, LG Alexopoulos, JPF Bai
CPT: pharmacometrics & systems pharmacology 7 (3), 166-174, 2018
122018
A crowd-sourcing approach for the construction of species-specific cell signaling networks
E Bilal, T Sakellaropoulos, C Participants, IN Melas, DE Messinis, ...
Bioinformatics 31 (4), 484-491, 2015
122015
Advances in omics for informed pharmaceutical research and development in the era of systems medicine
JPF Bai, IN Melas, J Hur, E Guo
Expert opinion on drug discovery 13 (1), 1-4, 2018
102018
Leveraging systems biology approaches in clinical pharmacology
IN Melas, K Kretsos, LG Alexopoulos
Biopharmaceutics & drug disposition 34 (9), 477-488, 2013
72013
Construction of signaling pathways and identification of drug effects on the liver cancer cell HepG2
LG Alexopoulos, IN Melas, AD Chairakaki, J Saez-Rodriguez, A Mitsos
2010 Annual International Conference of the IEEE Engineering in Medicine and …, 2010
72010
Network‐based analysis of nutraceuticals in human hepatocellular carcinomas reveals mechanisms of chemopreventive action
M Michailidou, IN Melas, DE Messinis, S Klamt, LG Alexopoulos, ...
CPT: pharmacometrics & systems pharmacology 4 (6), 350-361, 2015
62015
Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury. Integr Biol
IN Melas, T Sakellaropoulos, F Iorio, LG Alexopoulos, WY Loh, ...
Royal Society of Chemistry, 2015
52015
Network reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theory
V Stavrakas, IN Melas, T Sakellaropoulos, LG Alexopoulos
PloS one 10 (5), e0128411, 2015
52015
Das System kann den Vorgang jetzt nicht ausführen. Versuchen Sie es später erneut.
Artikel 1–20