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Piotr Stępnicki
Piotr Stępnicki
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Title
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Cited by
Year
Current concepts and treatments of schizophrenia
P Stępnicki, M Kondej, AA Kaczor
Molecules 23 (8), 2087, 2018
5102018
Multi-target approach for drug discovery against schizophrenia
M Kondej, P Stępnicki, AA Kaczor
International journal of molecular sciences 19 (10), 3105, 2018
982018
Overcoming Depression with 5-HT2A Receptor Ligands
A Zięba, P Stępnicki, D Matosiuk, AA Kaczor
International Journal of Molecular Sciences 23 (1), 10, 2021
272021
Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1, 2, 3, 6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs
M Kondej, TM Wróbel, AG Silva, P Stępnicki, O Koszła, E Kędzierska, ...
European Journal of Medicinal Chemistry 180, 673-689, 2019
222019
Multi-targeted drug design strategies for the treatment of schizophrenia
P Stępnicki, M Kondej, O Koszła, J Żuk, AA Kaczor
Expert opinion on drug discovery 16 (1), 101-114, 2021
192021
What are the challenges with multi-targeted drug design for complex diseases?
A Zięba, P Stępnicki, D Matosiuk, AA Kaczor
Expert Opinion on Drug Discovery 17 (7), 673-683, 2022
152022
Current approaches and tools used in drug development against parkinson’s disease
O Koszła, P Stępnicki, A Zięba, A Grudzińska, D Matosiuk, AA Kaczor
Biomolecules 11 (6), 897, 2021
122021
N-(3-{4-[3-(trifluoromethyl) phenyl] piperazin-1-yl} propyl)-1H-indazole-3-carboxamide (D2AAK3) as a potential antipsychotic: In vitro, in silico and in vivo evaluation of a …
AA Kaczor, KM Targowska-Duda, P Stępnicki, AG Silva, O Koszła, ...
Neurochemistry International 146, 105016, 2021
112021
Multitarget derivatives of D2AAK1 as potential antipsychotics: the effect of substitution in the indole moiety
M Kondej, TM Wróbel, KM Targowska‐Duda, A Leandro Martínez, ...
ChemMedChem 17 (15), e202200238, 2022
52022
The antipsychotic D2AAK1 as a memory enhancer for treatment of mental and neurodegenerative diseases
O Koszła, P Sołek, S Woźniak, E Kędzierska, TM Wróbel, M Kondej, ...
International Journal of Molecular Sciences 21 (22), 8849, 2020
52020
Experimental and computational structural studies of 5-substituted-3-(1-Arylmethyl-1, 2, 3, 6-Tetrahydropyridin-4-Yl)-1H-Indoles
A Bartyzel, M Kondej, P Stępnicki, TM Wróbel, AA Kaczor
Journal of Molecular Structure 1245, 130998, 2021
22021
Effects of small molecules on neurogenesis: Neuronal proliferation and differentiation
MK Jastrzębski, P Wójcik, P Stępnicki, AA Kaczor
Acta Pharmaceutica Sinica B, 2023
12023
Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents–Design, synthesis, structural studies and pharmacological profiling
P Stępnicki, KM Targowska-Duda, AL Martínez, A Zięba, ...
European Journal of Medicinal Chemistry 252, 115285, 2023
12023
Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
D Bartuzi, E Kędzierska, KM Targowska-Duda, O Koszła, TM Wróbel, ...
Scientific Reports 12 (1), 21192, 2022
12022
Screening and structure–activity relationship of D2AAK1 derivatives for potential application in the treatment of neurodegenerative diseases
O Koszła, P Sołek, P Stępnicki, AA Kaczor
Molecules 27 (7), 2239, 2022
12022
Discovery and in vitro Evaluation of Novel Serotonin 5‐HT2A Receptor Ligands Identified Through Virtual Screening
A Zięba, D Bartuzi, P Stępnicki, D Matosiuk, TM Wróbel, T Laitinen, ...
ChemMedChem, e202400080, 2024
2024
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds–synthesis, biological activity, and …
P Stępnicki, O Wronikowska-Denysiuk, A Zięba, KM Targowska-Duda, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2209828, 2023
2023
Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia
P Stępnicki, S Wośko, A Bartyzel, A Zięba, D Bartuzi, K Szałaj, TM Wróbel, ...
Molecules 28 (10), 4211, 2023
2023
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