Mathijs Vleugel
Mathijs Vleugel
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Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface
JPI Welburn, M Vleugel, D Liu, JR Yates III, MA Lampson, T Fukagawa, ...
Molecular cell 38 (3), 383-392, 2010
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
D Liu, M Vleugel, CB Backer, T Hori, T Fukagawa, IM Cheeseman, ...
Journal of Cell Biology 188 (6), 809-820, 2010
Integration of kinase and phosphatase activities by BUBR1 ensures formation of stable kinetochore-microtubule attachments
SJE Suijkerbuijk, M Vleugel, A Teixeira, GJPL Kops
Developmental cell 23 (4), 745-755, 2012
Evolution and function of the mitotic checkpoint
M Vleugel, E Hoogendoorn, B Snel, GJPL Kops
Developmental cell 23 (2), 239-250, 2012
The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase
SJE Suijkerbuijk, TJP van Dam, GE Karagöz, E von Castelmur, ...
Developmental cell 22 (6), 1321-1329, 2012
A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B
W Nijenhuis, E Von Castelmur, D Littler, V De Marco, E Tromer, M Vleugel, ...
Journal of Cell Biology 201 (2), 217-231, 2013
Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation
M Vleugel, E Tromer, M Omerzu, V Groenewold, W Nijenhuis, B Snel, ...
Journal of Cell Biology 203 (6), 943-955, 2013
A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
K Overlack, I Primorac, M Vleugel, V Krenn, S Maffini, I Hoffmann, ...
Elife 4, e05269, 2015
Sequential multisite phospho-regulation of KNL1-BUB3 interfaces at mitotic kinetochores
M Vleugel, M Omerzu, V Groenewold, MA Hadders, SMA Lens, ...
Molecular cell 57 (5), 824-835, 2015
Mps1 promotes rapid centromere accumulation of Aurora B
MS Van Der Waal, AT Saurin, MJM Vromans, M Vleugel, C Wurzenberger, ...
EMBO reports 13 (9), 847-854, 2012
Dissecting the roles of human BUB1 in the spindle assembly checkpoint
M Vleugel, TA Hoek, E Tromer, T Sliedrecht, V Groenewold, M Omerzu, ...
J Cell Sci 128 (16), 2975-2982, 2015
Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing
RCC Hengeveld, MJM Vromans, M Vleugel, MA Hadders, SMA Lens
Nature communications 8 (1), 1-12, 2017
A unique residue in rab3c determines the interaction with novel binding protein Zwint‐1
T van Vlijmen, M Vleugel, M Evers, S Mohammed, PS Wulf, AJR Heck, ...
FEBS letters 582 (19), 2838-2842, 2008
Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets
M Vleugel, S Roth, C Groenendijk, M Dogterom
Journal of Visualised Experiments 114, 2016
Understanding force-generating microtubule systems through in vitro reconstitution
M Vleugel, M Kok, M Dogterom
Cell adhesion & migration 10 (5), 475-494, 2016
Guided by light: Optical control of microtubule gliding assays
RP Tas, CY Chen, EA Katrukha, M Vleugel, M Kok, M Dogterom, ...
Nano letters 18 (12), 7524-7528, 2018
Reconstitution of basic mitotic spindles in cell-like confinement
S Roth, IC Gârlea, M Vleugel, BM Mulder, M Dogterom
bioRxiv, 770602, 2019
Evolution and regulation of mitotic checkpoint protein recruitment by the kinetochore scaffold KNL1
M Vleugel
Utrecht University, 2014
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