| Metalloproteases meprin α and meprin β are C-and N-procollagen proteinases important for collagen assembly and tensile strength C Broder, P Arnold, S Vadon-Le Goff, MA Konerding, K Bahr, S Müller, ... Proceedings of the National Academy of Sciences 110 (35), 14219-14224, 2013 | 145 | 2013 |
| Detection of neuron-derived pathological α-synuclein in blood A Kluge, J Bunk, E Schaeffer, A Drobny, W Xiang, H Knacke, S Bub, ... Brain 145 (9), 3058-3071, 2022 | 98 | 2022 |
| Meprin α and meprin β: Procollagen proteinases in health and disease J Prox, P Arnold, C Becker-Pauly Matrix Biology 44, 7-13, 2015 | 87 | 2015 |
| ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling S Schmidt, N Schumacher, J Schwarz, S Tangermann, L Kenner, ... Journal of Experimental Medicine 215 (4), 1205-1225, 2018 | 68 | 2018 |
| Alpha synuclein connects the gut-brain axis in Parkinson’s disease patients–a view on clinical aspects, cellular pathology and analytical methodology E Schaeffer, A Kluge, M Böttner, F Zunke, F Cossais, D Berg, P Arnold Frontiers in cell and developmental biology 8, 573696, 2020 | 65 | 2020 |
| Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2 F Zunke, L Andresen, S Wesseler, J Groth, P Arnold, M Rothaug, ... Proceedings of the National Academy of Sciences 113 (14), 3791-3796, 2016 | 60 | 2016 |
| Meprin metalloproteases generate biologically active soluble interleukin-6 receptor to induce trans-signaling P Arnold, I Boll, M Rothaug, N Schumacher, F Schmidt, R Wichert, ... Scientific reports 7 (1), 44053, 2017 | 58 | 2017 |
| Meprin metalloproteases: molecular regulation and function in inflammation and fibrosis P Arnold, A Otte, C Becker-Pauly Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (11), 2096-2104, 2017 | 47 | 2017 |
| Prdx4 limits caspase‐1 activation and restricts inflammasome‐mediated signaling by extracellular vesicles S Lipinski, S Pfeuffer, P Arnold, C Treitz, K Aden, H Ebsen, ... The EMBO journal 38 (20), e101266, 2019 | 41 | 2019 |
| EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors N Dudvarski Stanković, F Bicker, S Keller, DTW Jones, PN Harter, ... EMBO molecular medicine 10 (9), e8420, 2018 | 41 | 2018 |
| Mutations in the B. 1.1. 7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold Biomedicines 9 (5), 525, 2021 | 39 | 2021 |
| Pathophysiological processes in multiple sclerosis: focus on nuclear factor erythroid-2-related factor 2 and emerging pathways P Arnold, D Mojumder, J DeToledo, R Lucius, H Wilms Clinical Pharmacology: Advances and Applications, 35-42, 2014 | 39 | 2014 |
| Cathepsin D variants associated with neurodegenerative diseases show dysregulated functionality and modified α-synuclein degradation properties J Bunk, S Prieto Huarcaya, A Drobny, JP Dobert, L Walther, S Rose-John, ... Frontiers in cell and developmental biology 9, 581805, 2021 | 38 | 2021 |
| Enhanced stability of a chimeric hepatitis B core antigen virus-like-particle (HBcAg-VLP) by a C-terminal linker-hexahistidine-peptide J Schumacher, T Bacic, R Staritzbichler, M Daneschdar, T Klamp, ... Journal of nanobiotechnology 16, 1-21, 2018 | 37 | 2018 |
| Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding F Jäckle, F Schmidt, R Wichert, P Arnold, J Prox, M Mangold, A Ohler, ... Biochemical Journal 470 (1), 91-103, 2015 | 37 | 2015 |
| An L 2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16 T Bund, GA Spoden, K Koynov, N Hellmann, F Boukhallouk, P Arnold, ... Cellular microbiology 16 (8), 1179-1200, 2014 | 37 | 2014 |
| Anti-inflammatory properties of Honokiol in activated primary microglia and astrocytes U Rickert, F Cossais, M Heimke, P Arnold, A Preuße-Prange, H Wilms, ... Journal of Neuroimmunology 323, 78-86, 2018 | 36 | 2018 |
| Formate–nitrite transporters carrying nonprotonatable amide amino acids instead of a central histidine maintain pH-dependent transport F Helmstetter, P Arnold, B Höger, LM Petersen, E Beitz Journal of Biological Chemistry 294 (2), 623-631, 2019 | 35 | 2019 |
| Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike–ACE2 complexes reveal distinct changes between both variants E Socher, L Heger, F Paulsen, F Zunke, P Arnold Computational and structural biotechnology journal 20, 1168-1176, 2022 | 34 | 2022 |
| Mucus detachment by host metalloprotease meprin β requires shedding of its inactive pro-form, which is abrogated by the pathogenic protease RgpB R Wichert, A Ermund, S Schmidt, M Schweinlin, M Ksiazek, P Arnold, ... Cell reports 21 (8), 2090-2103, 2017 | 34 | 2017 |
