| Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets J McLauchlan, MK Lemberg, G Hope, B Martoglio The EMBO journal, 2002 | 662 | 2002 |
| Identification of signal peptide peptidase, a presenilin-type aspartic protease A Weihofen, K Binns, MK Lemberg, K Ashman, B Martoglio Science 296 (5576), 2215-2218, 2002 | 655 | 2002 |
| The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking C Meissner, H Lorenz, A Weihofen, DJ Selkoe, MK Lemberg Journal of neurochemistry 117 (5), 856-867, 2011 | 428 | 2011 |
| Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis MK Lemberg, B Martoglio Molecular cell 10 (4), 735-744, 2002 | 283 | 2002 |
| Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases MK Lemberg, M Freeman Genome research 17 (11), 1634-1646, 2007 | 276 | 2007 |
| Proteolytic ectodomain shedding of membrane proteins in mammals—hardware, concepts, and recent developments SF Lichtenthaler, MK Lemberg, R Fluhrer The EMBO journal 37 (15), e99456, 2018 | 267 | 2018 |
| Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes MK Lemberg, FA Bland, A Weihofen, VM Braud, B Martoglio The Journal of Immunology 167 (11), 6441-6446, 2001 | 238 | 2001 |
| Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins L Fleig, N Bergbold, P Sahasrabudhe, B Geiger, L Kaltak, MK Lemberg Molecular cell 47 (4), 558-569, 2012 | 216 | 2012 |
| Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases MK Lemberg, J Menendez, A Misik, M Garcia, CM Koth, M Freeman The EMBO journal 24 (3), 464-472, 2005 | 188 | 2005 |
| Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine … A Weihofen, MK Lemberg, HL Ploegh, M Bogyo, B Martoglio Journal of Biological Chemistry 275 (40), 30951-30956, 2000 | 155 | 2000 |
| Targeting presenilin-type aspartic protease signal peptide peptidase with γ-secretase inhibitors A Weihofen, MK Lemberg, E Friedmann, H Rueeger, A Schmitz, ... Journal of Biological Chemistry 278 (19), 16528-16533, 2003 | 154 | 2003 |
| Mammalian EGF receptor activation by the rhomboid protease RHBDL2 C Adrain, K Strisovsky, M Zettl, L Hu, MK Lemberg, M Freeman EMBO reports 12 (5), 421-427, 2011 | 128 | 2011 |
| Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins E Friedmann, MK Lemberg, A Weihofen, KK Dev, U Dengler, G Rovelli, ... Journal of Biological Chemistry 279 (49), 50790-50798, 2004 | 128 | 2004 |
| Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18 V Prod’homme, P Tomasec, C Cunningham, MK Lemberg, RJ Stanton, ... The Journal of Immunology 188 (6), 2794-2804, 2012 | 127 | 2012 |
| Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP 1u C Chen, NS Malchus, B Hehn, W Stelzer, D Avci, D Langosch, ... The EMBO journal 33 (21), 2492-2506, 2014 | 122 | 2014 |
| Understanding intramembrane proteolysis: from protein dynamics to reaction kinetics D Langosch, C Scharnagl, H Steiner, MK Lemberg Trends in biochemical sciences 40 (6), 318-327, 2015 | 118 | 2015 |
| Post-targeting functions of signal peptides K Kapp, S Schrempf, MK Lemberg, B Dobberstein Protein transport into the endoplasmic reticulum 1, 1-16, 2009 | 100 | 2009 |
| Intramembrane protease PARL defines a negative regulator of PINK1-and PARK2/Parkin-dependent mitophagy C Meissner, H Lorenz, B Hehn, MK Lemberg Autophagy 11 (9), 1484-1498, 2015 | 95 | 2015 |
| Clipping or extracting: two ways to membrane protein degradation D Avci, MK Lemberg Trends in cell biology 25 (10), 611-622, 2015 | 88 | 2015 |
| Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins V Dederer, A Khmelinskii, AG Huhn, V Okreglak, M Knop, MK Lemberg elife 8, e45506, 2019 | 85 | 2019 |
Michael KnopUniversity of HeidelbergBestätigte E-Mail-Adresse bei zmbh.uni-heidelberg.de
