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Gonçalo de Castro Pereira
Gonçalo de Castro Pereira
Senior Project Scientist, Nanna Therapeutics (part of Astellas Group)
Dirección de correo verificada de astellas.com
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Drug-induced Cardiac Mitochondrial Toxicity and Protection: From Doxorubicin to Carvedilol
G C Pereira, A M Silva, C V Diogo, F S Carvalho, P Monteiro, P J Oliveira
Current Pharmaceutical Design 17 (20), 2113-2129, 2011
1652011
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5, 6-dihydro-9, 10-dimethoxybenzo (g)-1, 3-benzodioxolo (5, 6-a) quinolizinium] on K1735-M2 mouse melanoma …
GC Pereira, AF Branco, JAC Matos, SL Pereira, D Parke, EL Perkins, ...
Journal of Pharmacology and Experimental Therapeutics 323 (2), 636-649, 2007
1632007
The role of succinate and ROS in reperfusion injury–a critical appraisal
TN Andrienko, P Pasdois, GC Pereira, MJ Ovens, AP Halestrap
Journal of molecular and cellular cardiology 110, 1-14, 2017
1492017
Protein CoAlation: a redox-regulated protein modification by coenzyme A in mammalian cells
Y Tsuchiya, SY Peak-Chew, C Newell, S Miller-Aidoo, S Mangal, ...
Biochemical Journal 474 (14), 2489-2508, 2017
862017
Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage
S Cardoso, RX Santos, C Carvalho, S Correia, GC Pereira, SS Pereira, ...
Free Radical Biology and Medicine 45 (10), 1395-1402, 2008
852008
Fumarate induces vesicular release of mtDNA to drive innate immunity
V Zecchini, V Paupe, I Herranz-Montoya, J Janssen, IMN Wortel, JL Morris, ...
Nature 615 (7952), 499-506, 2023
842023
Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells—Nuclear vs. mitochondrial effects
TL Serafim, JAC Matos, VA Sardao, GC Pereira, AF Branco, SL Pereira, ...
biochemical pharmacology 76 (11), 1459-1475, 2008
662008
The role of hexokinase in cardioprotection–mechanism and potential for translation
AP Halestrap, GC Pereira, P Pasdois
British journal of pharmacology 172 (8), 2085-2100, 2015
602015
A high-resolution luminescent assay for rapid and continuous monitoring of protein translocation across biological membranes
GC Pereira, WJ Allen, DW Watkins, L Buddrus, D Noone, X Liu, ...
Journal of molecular biology 431 (8), 1689-1699, 2019
482019
Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial function
GC Pereira, SP Pereira, LC Tavares, FS Carvalho, S Magalhães-Novais, ...
Mitochondrion 30, 95-104, 2016
462016
Mitochondrionopathy Phenotype in Doxorubicin-Treated Wistar Rats Depends on Treatment Protocol and Is Cardiac-Specific (vol 7, e38867, 2012)
GC Pereira, SP Pereira, C Pereira, JA Lumini, J Magalhaes
PLOS ONE 9 (5), 2014
45*2014
Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?
SP Pereira, GC Pereira, AJ Moreno, PJ Oliveira
Alternatives to Laboratory Animals 37 (4), 355-365, 2009
312009
Interplay between mitochondrial protein import and respiratory complexes assembly in neuronal health and degeneration
HI Needs, M Protasoni, JM Henley, J Prudent, I Collinson, GC Pereira
Life 11 (5), 432, 2021
272021
New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death
TL Serafim, FS Carvalho, TC Bernardo, GC Pereira, E Perkins, J Holy, ...
Bioorganic & Medicinal Chemistry 22 (21), 6270-6287, 2014
272014
Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung
NG Machado, I Baldeiras, GC Pereira, SP Pereira, PJ Oliveira
Chemico-biological interactions 188 (3), 478-486, 2010
272010
Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health
A Knapp-Wilson, GC Pereira, E Buzzard, HC Ford, A Richardson, ...
Journal of Cell Science 134 (13), jcs258399, 2021
232021
Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats
SP Pereira, GC Pereira, CV Pereira, FS Carvalho, MH Cordeiro, PC Mota, ...
Environmental pollution 180, 281-290, 2013
232013
Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes
HC Ford, WJ Allen, GC Pereira, X Liu, MS Dillingham, I Collinson
Elife 11, e75426, 2022
202022
Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats
AC Moreira, AM Silva, AF Branco, I Baldeiras, GC Pereira, R Seiça, ...
Journal of functional foods 34, 329-339, 2017
102017
Pharmacological strategies to counteract doxorubicin-induced cardiotoxicity: the role of mitochondria
GC Pereira, PJ Oliveira
J Theor Exp Pharm 1 (2), 39-53, 2008
102008
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20