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Thomas Durcan
Thomas Durcan
The Neuro's Early Drug Discovery Unit (EDDU), McGill University
Verified email at mcgill.ca - Homepage
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13149*2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106782021
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
TM Durcan, EA Fon
Genes & development 29 (10), 989-999, 2015
3952015
USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin
TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ...
The EMBO journal 33 (21), 2473-2491, 2014
3762014
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ...
Elife 7, e32866, 2018
3032018
The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
TM Durcan, M Kontogiannea, T Thorarinsdottir, L Fallon, AJ Williams, ...
Human molecular genetics 20 (1), 141-154, 2011
1732011
Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles
RF Roberts, MY Tang, EA Fon, TM Durcan
The international journal of biochemistry & cell biology 79, 427-436, 2016
1132016
Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme
TM Durcan, M Kontogiannea, N Bedard, SS Wing, EA Fon
Journal of Biological Chemistry 287 (1), 531-541, 2012
882012
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
C Laflamme, PM McKeever, R Kumar, J Schwartz, M Kolahdouzan, ...
Elife 8, e48363, 2019
832019
The neglected genes of ALS: Cytoskeletal dynamics impact synaptic degeneration in ALS
MJ Castellanos-Montiel, M Chaineau, TM Durcan
Frontiers in cellular neuroscience 14, 594975, 2020
602020
Disruption of GRIN2B impairs differentiation in human neurons
S Bell, G Maussion, M Jefri, H Peng, JF Theroux, H Silveira, V Soubannier, ...
Stem cell reports 11 (1), 183-196, 2018
592018
Coming soon to a journal near you—the updated guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky
Autophagy 10 (10), 1691-1691, 2014
572014
The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13
MA Aguileta, J Korac, TM Durcan, JF Trempe, M Haber, K Gehring, ...
Journal of Biological Chemistry 290 (12), 7492-7505, 2015
492015
Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery
V Soubannier, G Maussion, M Chaineau, V Sigutova, G Rouleau, ...
Neuroscience letters 731, 135028, 2020
482020
Ataxin-3 and its E3 partners: implications for Machado–Joseph disease
TM Durcan, EA Fon
Frontiers in neurology 4, 45552, 2013
472013
Cyberinfrastructure for open science at the Montreal Neurological Institute
S Das, T Glatard, C Rogers, J Saigle, S Paiva, L MacIntyre, M Safi-Harab, ...
Frontiers in neuroinformatics 10, 53, 2017
462017
Guidelines for the use and interpretation of assays for monitoring autophagy 1
D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1-382, 2021
44*2021
Mutant ataxin-3 promotes the autophagic degradation of parkin
TM Durcan, EA Fon
Autophagy 7 (2), 233-234, 2011
442011
USP8 and PARK2/parkin-mediated mitophagy
TM Durcan, EA Fon
Autophagy 11 (2), 428-429, 2015
432015
Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method
TC Scanlon, B Gottlieb, TM Durcan, EA Fon, LK Beitel, MA Trifiro
Experimental cell research 315 (2), 176-189, 2009
432009
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Articles 1–20