Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13149* | 2021 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10678 | 2021 |
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications TM Durcan, EA Fon Genes & development 29 (10), 989-999, 2015 | 395 | 2015 |
USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ... The EMBO journal 33 (21), 2473-2491, 2014 | 376 | 2014 |
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ... Elife 7, e32866, 2018 | 303 | 2018 |
The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability TM Durcan, M Kontogiannea, T Thorarinsdottir, L Fallon, AJ Williams, ... Human molecular genetics 20 (1), 141-154, 2011 | 173 | 2011 |
Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles RF Roberts, MY Tang, EA Fon, TM Durcan The international journal of biochemistry & cell biology 79, 427-436, 2016 | 113 | 2016 |
Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme TM Durcan, M Kontogiannea, N Bedard, SS Wing, EA Fon Journal of Biological Chemistry 287 (1), 531-541, 2012 | 88 | 2012 |
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72 C Laflamme, PM McKeever, R Kumar, J Schwartz, M Kolahdouzan, ... Elife 8, e48363, 2019 | 83 | 2019 |
The neglected genes of ALS: Cytoskeletal dynamics impact synaptic degeneration in ALS MJ Castellanos-Montiel, M Chaineau, TM Durcan Frontiers in cellular neuroscience 14, 594975, 2020 | 60 | 2020 |
Disruption of GRIN2B impairs differentiation in human neurons S Bell, G Maussion, M Jefri, H Peng, JF Theroux, H Silveira, V Soubannier, ... Stem cell reports 11 (1), 183-196, 2018 | 59 | 2018 |
Coming soon to a journal near you—the updated guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky Autophagy 10 (10), 1691-1691, 2014 | 57 | 2014 |
The E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13 MA Aguileta, J Korac, TM Durcan, JF Trempe, M Haber, K Gehring, ... Journal of Biological Chemistry 290 (12), 7492-7505, 2015 | 49 | 2015 |
Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery V Soubannier, G Maussion, M Chaineau, V Sigutova, G Rouleau, ... Neuroscience letters 731, 135028, 2020 | 48 | 2020 |
Ataxin-3 and its E3 partners: implications for Machado–Joseph disease TM Durcan, EA Fon Frontiers in neurology 4, 45552, 2013 | 47 | 2013 |
Cyberinfrastructure for open science at the Montreal Neurological Institute S Das, T Glatard, C Rogers, J Saigle, S Paiva, L MacIntyre, M Safi-Harab, ... Frontiers in neuroinformatics 10, 53, 2017 | 46 | 2017 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1-382, 2021 | 44* | 2021 |
Mutant ataxin-3 promotes the autophagic degradation of parkin TM Durcan, EA Fon Autophagy 7 (2), 233-234, 2011 | 44 | 2011 |
USP8 and PARK2/parkin-mediated mitophagy TM Durcan, EA Fon Autophagy 11 (2), 428-429, 2015 | 43 | 2015 |
Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method TC Scanlon, B Gottlieb, TM Durcan, EA Fon, LK Beitel, MA Trifiro Experimental cell research 315 (2), 176-189, 2009 | 43 | 2009 |