Machine learning meets continuous flow chemistry: Automated optimization towards the Pareto front of multiple objectives AM Schweidtmann, AD Clayton, N Holmes, E Bradford, RA Bourne, ... Chemical Engineering Journal 352, 277-282, 2018 | 333 | 2018 |
Algorithms for the self-optimisation of chemical reactions AD Clayton, JA Manson, CJ Taylor, TW Chamberlain, BA Taylor, ... Reaction Chemistry & Engineering 4 (9), 1545-1554, 2019 | 137 | 2019 |
Automated self-optimisation of multi-step reaction and separation processes using machine learning AD Clayton, AM Schweidtmann, G Clemens, JA Manson, CJ Taylor, ... Chemical Engineering Journal 384, 123340, 2020 | 135 | 2020 |
Simple and versatile laboratory scale CSTR for multiphasic continuous-flow chemistry and long residence times MR Chapman, MHT Kwan, G King, KE Jolley, M Hussain, S Hussain, ... Organic Process Research & Development 21 (9), 1294-1301, 2017 | 104 | 2017 |
Highly efficient aqueous phase reduction of nitroarenes catalyzed by phosphine-decorated polymer immobilized ionic liquid stabilized PdNPs S Doherty, JG Knight, T Backhouse, A Bradford, F Saunders, RA Bourne, ... Catalysis Science & Technology 8 (5), 1454-1467, 2018 | 68 | 2018 |
Kinetic treatments for catalyst activation and deactivation processes based on variable time normalization analysis A Martínez‐Carrión, MG Howlett, C Alamillo‐Ferrer, AD Clayton, ... Angewandte Chemie International Edition 58 (30), 10189-10193, 2019 | 64 | 2019 |
Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis AD Clayton, EO Pyzer‐Knapp, M Purdie, MF Jones, A Barthelme, J Pavey, ... Angewandte Chemie 135 (3), e202214511, 2023 | 57 | 2023 |
Machine learning directed multi-objective optimization of mixed variable chemical systems OJ Kershaw, AD Clayton, JA Manson, A Barthelme, J Pavey, P Peach, ... Chemical Engineering Journal 451, 138443, 2023 | 46 | 2023 |
Automated multi-objective reaction optimisation: which algorithm should I use? P Müller, AD Clayton, J Manson, S Riley, OS May, N Govan, S Notman, ... Reaction Chemistry & Engineering 7 (4), 987-993, 2022 | 41 | 2022 |
Self-optimising reactive extractions: towards the efficient development of multi-step continuous flow processes AD Clayton, LA Power, WR Reynolds, C Ainsworth, DRJ Hose, MF Jones, ... Journal of Flow Chemistry 10, 199-206, 2020 | 24 | 2020 |
Combination of chemocatalysis and biocatalysis in flow AD Clayton, R Labes, AJ Blacker Current Opinion in Green and Sustainable Chemistry 26, 100378, 2020 | 20 | 2020 |
Automated stopped-flow library synthesis for rapid optimisation and machine learning directed experimentation C Avila, C Cassani, T Kogej, J Mazuela, S Sarda, AD Clayton, ... Chemical Science 13 (41), 12087-12099, 2022 | 19 | 2022 |
A hybridised optimisation of an automated photochemical continuous flow reactor JA Manson, AD Clayton, CG Niño, R Labes, TW Chamberlain, AJ Blacker, ... Chimia 73 (10), 817-817, 2019 | 18 | 2019 |
Recent Developments in Reactor Automation for Multistep Chemical Synthesis AD Clayton Chemistry‐Methods 3 (12), e202300021, 2023 | 10 | 2023 |
Catalytic sp3–sp3 Functionalisation of Sulfonamides: Late‐Stage Modification of Drug‐Like Molecules O Abdulla, AD Clayton, RA Faulkner, DM Gill, CR Rice, SM Walton, ... Chemistry–A European Journal 23 (7), 1494-1497, 2017 | 10 | 2017 |
Selective separation of amines from continuous processes using automated pH controlled extraction LA Power, AD Clayton, WR Reynolds, DRJ Hose, C Ainsworth, ... Reaction Chemistry & Engineering 6 (10), 1806-1810, 2021 | 7 | 2021 |
Adaptive mixed variable Bayesian self-optimisation of catalytic reactions N Aldulaijan, JA Marsden, JA Manson, AD Clayton Reaction Chemistry & Engineering 9 (2), 308-316, 2024 | 6 | 2024 |
Exploring the chemical space of phenyl sulfide oxidation by automated optimization P Mueller, A Vriza, AD Clayton, OS May, N Govan, S Notman, SV Ley, ... Reaction Chemistry & Engineering 8 (3), 538-542, 2023 | 3 | 2023 |
A self-optimised approach to synthesising DEHiBA for advanced nuclear reprocessing, exploiting the power of machine-learning T Shaw, AD Clayton, R Labes, TM Dixon, S Boyall, OJ Kershaw, ... Reaction Chemistry & Engineering 9 (2), 426-438, 2024 | 2 | 2024 |
A practical experiment to teach students continuous flow and physico-chemical methods: acetylation of ethylene diamine in liquid bi-phase M Bayana, AJ Blacker, AD Clayton, KE Jolley, R Labes, CJ Taylor, ... Journal of Flow Chemistry 11, 31-36, 2021 | 2 | 2021 |