Johannes-Peter Stasch
Johannes-Peter Stasch
Professor für Arzneimittelforschung; Chief Scientist Bayer AG
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Increased NADH-oxidase–mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system
A Warnholtz, G Nickenig, E Schulz, R Macharzina, JH Bräsen, ...
Circulation 99 (15), 2027-2033, 1999
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
OV Evgenov, P Pacher, PM Schmidt, G Haskó, HHHW Schmidt, JP Stasch
Nature reviews Drug discovery 5 (9), 755-768, 2006
NO-independent regulatory site on soluble guanylate cyclase
JP Stasch, EM Becker, C Alonso-Alija, H Apeler, K Dembowsky, A Feurer, ...
Nature 410 (6825), 212, 2001
Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease
JP Stasch, P Pacher, OV Evgenov
Circulation 123 (20), 2263-2273, 2011
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels
JP Stasch, PM Schmidt, PI Nedvetsky, TY Nedvetskaya, AK HS, S Meurer, ...
The Journal of clinical investigation 116 (9), 2552-2561, 2006
The concise guide to pharmacology 2019/20: Enzymes
SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ...
British Journal of Pharmacology 176, S297-S396, 2019
Continuous-wave Doppler echocardiographic detection of pulmonary regurgitation and its application to noninvasive estimation of pulmonary artery pressure.
T Masuyama, K Kodama, A Kitabatake, H Sato, S Nanto, M Inoue
Circulation 74 (3), 484-492, 1986
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
Y Wang, H Liu, G McKenzie, PK Witting, JP Stasch, M Hahn, ...
Nature medicine 16 (3), 279-285, 2010
NO‐and haem‐independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle
JP Stasch, P Schmidt, C Alonso‐Alija, H Apeler, K Dembowsky, M Haerter, ...
British journal of pharmacology 136 (5), 773-783, 2002
The concise guide to pharmacology 2021/22: Enzymes
SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ...
British journal of pharmacology 178, S313-S411, 2021
Effect of YC‐1, an NO‐independent, superoxide‐sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators
A Mülsch, J Bauersachs, A Schäfer, JP Stasch, R Kast, R Busse
British journal of pharmacology 120 (4), 681-689, 1997
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
RT Schermuly, JP Stasch, SS Pullamsetti, R Middendorff, D Müller, ...
European Respiratory Journal 32 (4), 881-891, 2008
Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling
R Dumitrascu, N Weissmann, HA Ghofrani, E Dony, K Beuerlein, ...
Circulation 113 (2), 286-295, 2006
NO-independent, haem-dependent soluble guanylate cyclase stimulators
JP Stasch, AJ Hobbs
cGMP: Generators, Effectors and Therapeutic Implications, 277-308, 2009
Discovery of riociguat (BAY 63‐2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension
J Mittendorf, S Weigand, C Alonso‐Alija, E Bischoff, A Feurer, M Gerisch, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 853-865, 2009
The chemistry and biology of soluble guanylate cyclase stimulators and activators
M Follmann, N Griebenow, MG Hahn, I Hartung, FJ Mais, J Mittendorf, ...
Angewandte Chemie International Edition 52 (36), 9442-9462, 2013
NO-independent stimulators of soluble guanylate cyclase
A Straub, JP Stasch, C Alonso-Alija, J Benet-Buchholz, B Ducke, A Feurer, ...
Bioorganic & Medicinal Chemistry Letters 11 (6), 781-784, 2001
Soluble guanylate cyclase stimulators in pulmonary hypertension
JP Stasch, OV Evgenov
Pharmacotherapy of Pulmonary Hypertension, 279-313, 2013
Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase
PM Schmidt, M Schramm, H Schröder, F Wunder, JP Stasch
Journal of Biological Chemistry 279 (4), 3025-3032, 2004
NO-and haem-independent soluble guanylate cyclase activators
HHHW Schmidt, PM Schmidt, JP Stasch
cGMP: Generators, Effectors and Therapeutic Implications, 309-339, 2009
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