| Cysteine proteases and their inhibitors HH Otto, T Schirmeister Chemical reviews 97 (1), 133-172, 1997 | 1032 | 1997 |
| Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors R Ettari, E Nizi, ME Di Francesco, MA Dude, G Pradel, R Vičík, ... Journal of medicinal chemistry 51 (4), 988-996, 2008 | 225 | 2008 |
| Biochemistry and medicinal chemistry of the dengue virus protease C Nitsche, S Holloway, T Schirmeister, CD Klein Chemical reviews 114 (22), 11348-11381, 2014 | 133 | 2014 |
| Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies LRF de Sousa, H Wu, L Nebo, JB Fernandes, W Kiefer, M Kanitz, ... Bioorganic & medicinal chemistry 23 (3), 466-470, 2015 | 128 | 2015 |
| Prospective evaluation of free energy calculations for the prioritization of Cathepsin L inhibitors B Kuhn, M Tichý, L Wang, S Robinson, RE Martin, A Kuglstatter, J Benz, ... Journal of medicinal chemistry 60 (6), 2485-2497, 2017 | 118 | 2017 |
| Novel dengue virus NS2B/NS3 protease inhibitors H Wu, S Bock, M Snitko, T Berger, T Weidner, S Holloway, M Kanitz, ... Antimicrobial agents and chemotherapy 59 (2), 1100-1109, 2015 | 117 | 2015 |
| Transcriptome and functional analysis of the eukaryotic-type serine/threonine kinase PknB in Staphylococcus aureus S Donat, K Streker, T Schirmeister, S Rakette, T Stehle, M Liebeke, M Lalk, ... Journal of bacteriology 191 (13), 4056-4069, 2009 | 117 | 2009 |
| Inhibitors of cysteine proteases R Vicik, M Busemann, K Baumann, T Schirmeister Current topics in medicinal chemistry 6 (4), 331-353, 2006 | 116 | 2006 |
| The Significance of Ionic Bonding in Sulfur Dioxide: Bond Orders from X‐ray Diffraction Data S Grabowsky, P Luger, J Buschmann, T Schneider, T Schirmeister, ... Angewandte Chemie International Edition 51 (27), 6776-6779, 2012 | 105 | 2012 |
| Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents R Vicik, V Hoerr, M Glaser, M Schultheis, E Hansell, JH McKerrow, ... Bioorganic & medicinal chemistry letters 16 (10), 2753-2757, 2006 | 105 | 2006 |
| Antioxidant and anti-protease activities of diazepinomicin from the sponge-associated Micromonospora strain RV115 UR Abdelmohsen, M Szesny, EM Othman, T Schirmeister, S Grond, ... Marine drugs 10 (10), 2208-2221, 2012 | 91 | 2012 |
| New peptidic cysteine protease inhibitors derived from the electrophilic α-amino acid aziridine-2, 3-dicarboxylic acid T Schirmeister Journal of medicinal chemistry 42 (4), 560-572, 1999 | 90 | 1999 |
| Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors R Ettari, N Micale, T Schirmeister, C Gelhaus, M Leippe, E Nizi, ... Journal of medicinal chemistry 52 (7), 2157-2160, 2009 | 88 | 2009 |
| Aziridine-2, 3-dicarboxylates, peptidomimetic cysteine protease inhibitors with antileishmanial activity A Ponte-Sucre, R Vicik, M Schultheis, T Schirmeister, H Moll Antimicrobial agents and chemotherapy 50 (7), 2439-2447, 2006 | 88 | 2006 |
| Allicin and derivates are cysteine protease inhibitors with antiparasitic activity T Waag, C Gelhaus, J Rath, A Stich, M Leippe, T Schirmeister Bioorganic & medicinal chemistry letters 20 (18), 5541-5543, 2010 | 83 | 2010 |
| Aziridinyl peptides as inhibitors of cysteine proteases: effect of a free carboxylic acid function on inhibition T Schirmeister, M Peric Bioorganic & medicinal chemistry 8 (6), 1281-1291, 2000 | 79 | 2000 |
| A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and … U Kaeppler, N Stiefl, M Schiller, R Vicik, A Breuning, W Schmitz, ... Journal of medicinal chemistry 48 (22), 6832-6842, 2005 | 76 | 2005 |
| Evidence for substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the SARS-CoV main protease A Paasche, A Zipper, S Schäfer, J Ziebuhr, T Schirmeister, B Engels Biochemistry 53 (37), 5930-5946, 2014 | 73 | 2014 |
| On the origin of the stabilization of the zwitterionic resting state of cysteine proteases: a theoretical study M Mladenovic, RF Fink, W Thiel, T Schirmeister, B Engels Journal of the American Chemical Society 130 (27), 8696-8705, 2008 | 73 | 2008 |
| Theoretical studies about the influence of different ring substituents on the nucleophilic ring opening of three-membered heterocycles and possible implications for the … H Helten, T Schirmeister, B Engels The Journal of organic chemistry 70 (1), 233-237, 2005 | 71 | 2005 |
