| Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter” K Grillone, C Riillo, F Scionti, R Rocca, G Tradigo, PH Guzzi, S Alcaro, ... Journal of Experimental & Clinical Cancer Research 39, 1-19, 2020 | 164 | 2020 |
| Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome D Bagetta, A Maruca, A Lupia, F Mesiti, R Catalano, I Romeo, F Moraca, ... European journal of medicinal chemistry 186, 111903, 2020 | 78 | 2020 |
| The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile A Maruca, R Catalano, D Bagetta, F Mesiti, FA Ambrosio, I Romeo, ... European journal of medicinal chemistry 181, 111579, 2019 | 72 | 2019 |
| Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types V Spano, R Rocca, M Barreca, D Giallombardo, A Montalbano, ... Journal of medicinal chemistry 63 (20), 12023-12042, 2020 | 44 | 2020 |
| Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization R Rocca, F Moraca, G Costa, M Nadai, M Scalabrin, C Talarico, S Distinto, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (5), 1329-1340, 2017 | 37 | 2017 |
| Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery? L Parrotta, F Ortuso, F Moraca, R Rocca, G Costa, S Alcaro, A Artese Expert opinion on drug discovery 9 (10), 1167-1187, 2014 | 37 | 2014 |
| Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity F Esposito, FA Ambrosio, R Maleddu, G Costa, R Rocca, E Maccioni, ... European Journal of Medicinal Chemistry 182, 111617, 2019 | 31 | 2019 |
| Molecular recognition of a carboxy pyridostatin toward G‐quadruplex structures: Why does it prefer RNA? R Rocca, C Talarico, F Moraca, G Costa, I Romeo, F Ortuso, S Alcaro, ... Chemical Biology & Drug Design 90 (5), 919-925, 2017 | 31 | 2017 |
| Insight on [1, 3] thiazolo [4, 5-e] isoindoles as tubulin polymerization inhibitors V Spanò, M Barreca, R Rocca, R Bortolozzi, R Bai, A Carbone, ... European Journal of Medicinal Chemistry 212, 113122, 2021 | 30 | 2021 |
| The non-coding RNA landscape of plasma cell dyscrasias E Morelli, A Gullà, R Rocca, C Federico, L Raimondi, S Malvestiti, ... Cancers 12 (2), 320, 2020 | 30 | 2020 |
| Structure-based virtual screening of novel natural alkaloid derivatives as potential binders of h-telo and c-myc DNA G-quadruplex conformations R Rocca, F Moraca, G Costa, S Alcaro, S Distinto, E Maccioni, F Ortuso, ... Molecules 20 (1), 206-223, 2015 | 30 | 2015 |
| Development of [1, 2] oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas M Barreca, V Spanò, R Rocca, R Bivacqua, AC Abel, A Maruca, ... European Journal of Medicinal Chemistry 243, 114744, 2022 | 29 | 2022 |
| Computer-based techniques for lead identification and optimization I: Basics A Maruca, FA Ambrosio, A Lupia, I Romeo, R Rocca, F Moraca, C Talarico, ... Physical Sciences Reviews 4 (6), 20180113, 2019 | 29 | 2019 |
| A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors G Costa, F Carta, FA Ambrosio, A Artese, F Ortuso, F Moraca, R Rocca, ... European Journal of Medicinal Chemistry 181, 111565, 2019 | 28 | 2019 |
| Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape-and structure-based virtual screening techniques G Costa, R Rocca, A Corona, N Grandi, F Moraca, I Romeo, C Talarico, ... European journal of medicinal chemistry 161, 1-10, 2019 | 28 | 2019 |
| A drug repurposing screening reveals a novel epigenetic activity of hydroxychloroquine R Catalano, R Rocca, G Juli, G Costa, A Maruca, A Artese, D Caracciolo, ... European Journal of Medicinal Chemistry 183, 111715, 2019 | 27 | 2019 |
| Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species A Maruca, F Moraca, R Rocca, F Molisani, F Alcaro, MC Gidaro, S Alcaro, ... Molecules 22 (9), 1571, 2017 | 27 | 2017 |
| Hit Identification of a Novel Dual Binder for h‐telo/c‐myc G‐Quadruplex by a Combination of Pharmacophore Structure‐Based Virtual Screening and Docking … R Rocca, G Costa, A Artese, L Parrotta, F Ortuso, E Maccioni, O Pinato, ... ChemMedChem 11 (16), 1721-1733, 2016 | 24 | 2016 |
| The new microtubule-targeting agent SIX2G induces immunogenic cell death in multiple myeloma K Grillone, C Riillo, R Rocca, S Ascrizzi, V Spanò, F Scionti, N Polerà, ... International Journal of Molecular Sciences 23 (18), 10222, 2022 | 23 | 2022 |
| Synthesis of 2H-Imidazo [2′, 1': 2, 3][1, 3] thiazolo [4, 5-e] isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML … V Cilibrasi, V Spano, R Bortolozzi, M Barreca, MV Raimondi, R Rocca, ... European Journal of Medicinal Chemistry 235, 114292, 2022 | 22 | 2022 |
