Alexandra (Sasha) Zhernakova

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Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerified email at umcg.nl
Jingyuan Fu, PhDProfessor, University Medical Center Groningen, NetherlandsVerified email at umcg.nl
Alexander KurilshikovUniversity Medical Center GroningenVerified email at umcg.nl
Rinse WeersmaMD PhD Professor, Chair Dept of Gastroenterology and Hepatology, University Medical Center GroningenVerified email at umcg.nl
Lude FrankeProfessor of Functional Genomics, University Medical Centre GroningenVerified email at cleverfranke.com
Arnau Vich VilaUniversity Medical Center GroningenVerified email at umcg.nl
Ettje F TigchelaarResearcher at University Medical Center GroningenVerified email at umcg.nl
Mihai NeteaVerified email at lembatherapeutics.com
Floris ImhannUniversity of GroningenVerified email at rug.nl
Marc Jan BonderPostdoctoral researcher UMCGVerified email at umcg.nl
Zlatan MujagicM.D., Ph.D., Division of Gastroenterology and Hepatology, Maastricht University Medical CenterVerified email at maastrichtuniversity.nl
Leo JoostenRadboud UMC Nijmegen, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-NapocaVerified email at radboudumc.nl
Serena SannaIRGB-CNR, ItalyVerified email at irgb.cnr.it
Gosia TrynkaGroup leaderVerified email at sanger.ac.uk
H.J.M. HarmsenVerified email at rug.nl
Eleonora FestenPost-doctoral Fellow and Gastroenterolist in training, Dept. of Gastroenterology, University MedicalVerified email at umcg.nl
T.W.J. HuizingaLeiden University Medical CenterVerified email at lumc.nl
Bobby P C KoelemanMedical Genetics, University Medical Center Utrecht, The NetherlandsVerified email at umcutrecht.nl
Marten HofkerProfessor of Molecular Genetics, UMCG, Groningen University, The NetherlandsVerified email at umcg.nl
Morris SwertzFull Professor / Head of Genomics Coordination Center, Dept of Genetics, University MedicalVerified email at rug.nl

Alexandra (Sasha) Zhernakova

Professor of Human Genome and Exposome, University Medical Centre Groningen, The Netherlands

Verified email at umcg.nl - Homepage

Genetics autoimmune aging microbiome exposome


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Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014	2328	2014
Environment dominates over host genetics in shaping human gut microbiota D Rothschild, O Weissbrod, E Barkan, A Kurilshikov, T Korem, D Zeevi, ... Nature 555 (7695), 210-215, 2018	2202	2018
Population-level analysis of gut microbiome variation G Falony, M Joossens, S Vieira-Silva, J Wang, Y Darzi, K Faust, ... Science 352 (6285), 560-564, 2016	1992	2016
Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013	1836	2013
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity A Zhernakova, A Kurilshikov, MJ Bonder, EF Tigchelaar, M Schirmer, ... Science 352 (6285), 565-569, 2016	1601	2016
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010	1524	2010
The neuroactive potential of the human gut microbiota in quality of life and depression M Valles-Colomer, G Falony, Y Darzi, EF Tigchelaar, J Wang, RY Tito, ... Nature microbiology 4 (4), 623-632, 2019	1423	2019
Multiple common variants for celiac disease influencing immune gene expression PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ... Nature genetics 42 (4), 295-302, 2010	1166	2010
Gut microbiome structure and metabolic activity in inflammatory bowel disease EA Franzosa, A Sirota-Madi, J Avila-Pacheco, N Fornelos, HJ Haiser, ... Nature microbiology 4 (2), 293-305, 2019	1125	2019
Proton pump inhibitors affect the gut microbiome F Imhann, MJ Bonder, AV Vila, J Fu, Z Mujagic, L Vork, EF Tigchelaar, ... Gut 65 (5), 740-748, 2016	1055	2016
Linking the human gut microbiome to inflammatory cytokine production capacity M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ... Cell 167 (4), 1125-1136. e8, 2016	970	2016
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry, A Szperl, SF Bakker, ... Nature genetics 43 (12), 1193-1201, 2011	887	2011
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases S Sanna, NR van Zuydam, A Mahajan, A Kurilshikov, A Vich Vila, U Võsa, ... Nature genetics 51 (4), 600-605, 2019	830	2019
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 DA Van Heel, L Franke, KA Hunt, R Gwilliam, A Zhernakova, M Inouye, ... Nature genetics 39 (7), 827-829, 2007	817	2007
Newly identified genetic risk variants for celiac disease related to the immune response KA Hunt, A Zhernakova, G Turner, GAR Heap, L Franke, M Bruinenberg, ... Nature genetics 40 (4), 395-402, 2008	816	2008
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ... Nature 541 (7635), 81-86, 2017	802	2017
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012	718	2012
The effect of host genetics on the gut microbiome MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ... Nature genetics 48 (11), 1407-1412, 2016	693	2016
Detecting shared pathogenesis from the shared genetics of immune-related diseases A Zhernakova, CC Van Diemen, C Wijmenga Nature Reviews Genetics 10 (1), 43-55, 2009	653	2009
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease F Imhann, AV Vila, MJ Bonder, J Fu, D Gevers, MC Visschedijk, ... Gut 67 (1), 108-119, 2018	651	2018

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