| Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax J Gruszczyk, U Kanjee, LJ Chan, S Menant, B Malleret, NTY Lim, ... Science 359 (6371), 48-55, 2018 | 192 | 2018 |
| Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ... Nature communications 9 (1), 2422, 2018 | 173 | 2018 |
| Small heat-shock proteins prevent α-synuclein aggregation via transient interactions and their efficacy is affected by the rate of aggregation D Cox, E Selig, MDW Griffin, JA Carver, H Ecroyd Journal of Biological Chemistry 291 (43), 22618-22629, 2016 | 122 | 2016 |
| Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein AI YQ Wong, KJ Binger, GJ Howlett, MDW Griffin Proceedings of the National Academy of Sciences 107 (5), 1977-1982, 2010 | 114 | 2010 |
| Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen BR Burgess, RCJ Dobson, MF Bailey, SC Atkinson, MDW Griffin, ... Journal of biological chemistry 283 (41), 27598-27603, 2008 | 109 | 2008 |
| The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance RCJ Dobson, MDW Griffin, GB Jameson, JA Gerrard Acta Crystallographica Section D: Biological Crystallography 61 (8), 1116-1124, 2005 | 103 | 2005 |
| Evolution of quaternary structure in a homotetrameric enzyme MDW Griffin, RCJ Dobson, FG Pearce, L Antonio, AE Whitten, CK Liew, ... Journal of Molecular Biology 380 (4), 691-703, 2008 | 95 | 2008 |
| Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis G Kefala, GL Evans, MDW Griffin, SRA Devenish, FG Pearce, MA Perugini, ... Biochemical Journal 411 (2), 351-360, 2008 | 86 | 2008 |
| Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways MDW Griffin, MLY Mok, LM Wilson, CLL Pham, LJ Waddington, ... Journal of molecular biology 375 (1), 240-256, 2008 | 80 | 2008 |
| The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis KA Davies, MC Tanzer, MDW Griffin, YF Mok, SN Young, R Qin, EJ Petrie, ... Cell Death & Differentiation 25 (9), 1567-1580, 2018 | 79 | 2018 |
| Structural understanding of interleukin 6 family cytokine signaling and targeted therapies: focus on interleukin 11 RD Metcalfe, TL Putoczki, MDW Griffin Frontiers in immunology 11, 540177, 2020 | 77 | 2020 |
| A novel ultra-stable, monomeric green fluorescent protein for direct volumetric imaging of whole organs using CLARITY DJ Scott, NJ Gunn, KJ Yong, VC Wimmer, NA Veldhuis, LM Challis, ... Scientific reports 8 (1), 667, 2018 | 76 | 2018 |
| Apolipoproteins and amyloid fibril formation in atherosclerosis CL Teoh, MDW Griffin, GJ Howlett Protein & cell 2 (2), 116-127, 2011 | 72 | 2011 |
| Loss of NF-κB1 causes gastric cancer with aberrant inflammation and expression of immune checkpoint regulators in a STAT-1-dependent manner LA O’Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, ... Immunity 48 (3), 570-583. e8, 2018 | 70 | 2018 |
| Emerging roles for the IL-6 family of cytokines in pancreatic cancer G van Duijneveldt, MDW Griffin, TL Putoczki Clinical science 134 (16), 2091-2115, 2020 | 67 | 2020 |
| A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis LM Wilson, YF Mok, KJ Binger, MDW Griffin, HDT Mertens, F Lin, ... Journal of molecular biology 366 (5), 1639-1651, 2007 | 67 | 2007 |
| The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6 TL Putoczki, RCJ Dobson, MDW Griffin Acta Crystallographica Section D: Biological Crystallography 70 (9), 2277-2285, 2014 | 62 | 2014 |
| Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate RCJ Dobson, MDW Griffin, SJ Roberts, JA Gerrard Biochimie 86 (4-5), 311-315, 2004 | 61 | 2004 |
| Biochemical and structural insights into doublecortin-like kinase domain 1 O Patel, W Dai, M Mentzel, MDW Griffin, J Serindoux, Y Gay, S Fischer, ... Structure 24 (9), 1550-1561, 2016 | 59 | 2016 |
| Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax JE Voss, SW Scally, NL Taylor, SC Atkinson, MDW Griffin, CA Hutton, ... Journal of biological chemistry 285 (8), 5188-5195, 2010 | 59 | 2010 |
