Marcelo Kazanietz
Marcelo Kazanietz
University of Pennsylvania, Perelman School of Medicine
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Zitiert von
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Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976
G Martiny-Baron, MG Kazanietz, H Mischak, PM Blumberg, G Kochs, ...
Journal of Biological Chemistry 268 (13), 9194-9197, 1993
Protein kinase C and other diacylglycerol effectors in cancer
EM Griner, MG Kazanietz
Nature Reviews Cancer 7 (4), 281-294, 2007
Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester
G Zhang, MG Kazanietz, PM Blumberg, JH Hurley
Cell 81 (6), 917-924, 1995
New insights into the regulation of protein kinase C and novel phorbol ester receptors
D Ron, MG Kazanietz
The FASEB Journal 13 (13), 1658-1676, 1999
Overexpression of protein kinase C-delta and-epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
H Mischak, JA Goodnight, W Kolch, G Martiny-Baron, C Schaechtle, ...
Journal of Biological Chemistry 268 (9), 6090-6096, 1993
Ca (2+)-dependent and Ca (2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory …
K Ozawa, Z Szallasi, MG Kazanietz, PM Blumberg, H Mischak, ...
Journal of Biological Chemistry 268 (3), 1749-1756, 1993
Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes.
MG Kazanietz, LB Areces, A Bahador, H Mischak, J Goodnight, ...
Molecular Pharmacology 44 (2), 298-307, 1993
C1 domains exposed: from diacylglycerol binding to protein–protein interactions
F Colón-González, MG Kazanietz
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway
Y Tanaka, MV Gavrielides, Y Mitsuuchi, T Fujii, MG Kazanietz
Journal of Biological Chemistry 278 (36), 33753-33762, 2003
Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and-delta and not by protein kinase C-beta II,-epsilon,-zeta, and-eta.
H Mischak, JH Pierce, J Goodnight, MG Kazanietz, PM Blumberg, ...
Journal of Biological Chemistry 268 (27), 20110-20115, 1993
Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent …
OP Barry, MG Kazanietz, D Pratico, GA FitzGerald
Journal of Biological Chemistry 274 (11), 7545-7556, 1999
Divergence and complexities in DAG signaling: looking beyond PKC
CF Yang, MG Kazanietz
Trends in pharmacological sciences 24 (11), 602-608, 2003
Novel “nonkinase” phorbol ester receptors: the C1 domain connection
MG Kazanietz
Molecular pharmacology 61 (4), 759-767, 2002
Protein kinase C and cancer: what we know and what we do not
R Garg, LG Benedetti, MB Abera, H Wang, M Abba, MG Kazanietz
Oncogene 33 (45), 5225-5237, 2014
Involvement of protein kinase C δ (PKCδ) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells: lack of proteolytic cleavage of PKCδ
T Fujii, ML Garcı́a-Bermejo, JL Bernabó, J Caamaño, M Ohba, T Kuroki, ...
Journal of Biological Chemistry 275 (11), 7574-7582, 2000
Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters
MG Kazanietz
Molecular Carcinogenesis: Published in cooperation with the University of …, 2000
Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways
P Chinchilla, L Xiao, MG Kazanietz, NA Riobo
Cell cycle 9 (3), 570-579, 2010
Rac signaling in breast cancer: a tale of GEFs and GAPs
E Wertheimer, A Gutierrez-Uzquiza, C Rosemblit, C Lopez-Haber, ...
Cellular signalling 24 (2), 353-362, 2012
Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties
NM Jideama, TA Noland, RL Raynor, GC Blobe, D Fabbro, MG Kazanietz, ...
Journal of Biological Chemistry 271 (38), 23277-23283, 1996
Residues in the second cysteine-rich region of protein kinase C δ relevant to phorbol ester binding as revealed by site-directed mutagenesis
MG Kazanietz, S Wang, GWA Milne, NE Lewin, HL Liu, PM Blumberg
Journal of Biological Chemistry 270 (37), 21852-21859, 1995
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