Unique gene‐silencing and structural properties of 2′‐fluoro‐modified siRNAs M Manoharan, A Akinc, RK Pandey, J Qin, P Hadwiger, M John, K Mills, ... Angewandte Chemie 123 (10), 2332-2336, 2011 | 207 | 2011 |
Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA PS Pallan, EM Greene, PA Jicman, RK Pandey, M Manoharan, E Rozners, ... Nucleic acids research 39 (8), 3482-3495, 2011 | 191 | 2011 |
Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5 M Li, T Zengeya, E Rozners Journal of the American Chemical Society 132 (25), 8676-8681, 2010 | 126 | 2010 |
Parallel kinetic resolution under catalytic conditions: a three-phase system allows selective reagent activation using two catalysts E Vedejs, E Rozners Journal of the American Chemical Society 123 (10), 2428-2429, 2001 | 119 | 2001 |
Triple helical recognition of RNA using 2-aminopyridine-modified PNA at physiologically relevant conditions T Zengeya, P Gupta, E Rozners Angewandte Chemie (International ed. in English) 51 (50), 12593, 2012 | 109 | 2012 |
2′‐Fluoro RNA Shows Increased Watson–Crick H‐Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data A Patra, M Paolillo, K Charisse, M Manoharan, E Rozners, M Egli Angewandte Chemie International Edition 51 (47), 11863-11866, 2012 | 103 | 2012 |
Hydration of short DNA, RNA and 2′‐OMe oligonucleotides determined by osmotic stressing E Rozners, J Moulder Nucleic acids research 32 (1), 248-254, 2004 | 102 | 2004 |
Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions E Rozners, D Katkevica, E Bizdena, R Strömberg Journal of the American Chemical Society 125 (40), 12125-12136, 2003 | 84 | 2003 |
Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA P Gupta, T Zengeya, E Rozners Chemical Communications 47 (39), 11125-11127, 2011 | 70 | 2011 |
Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids P Gupta, O Muse, E Rozners Biochemistry 51 (1), 63-73, 2012 | 67 | 2012 |
Nucleobase‐Modified PNA Suppresses Translation by Forming a Triple Helix with a Hairpin Structure in mRNA In Vitro and in Cells T Endoh, D Hnedzko, E Rozners, N Sugimoto Angewandte Chemie International Edition 55 (3), 899-903, 2016 | 66 | 2016 |
Sequence-selective recognition of double-stranded RNA and enhanced cellular uptake of cationic nucleobase and backbone-modified peptide nucleic acids D Hnedzko, DW McGee, YA Karamitas, E Rozners Rna 23 (1), 58-69, 2017 | 60 | 2017 |
Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs D Mutisya, C Selvam, BD Lunstad, PS Pallan, A Haas, D Leake, M Egli, ... Nucleic acids research 42 (10), 6542-6551, 2014 | 60 | 2014 |
Amides Are Excellent Mimics of Phosphate Linkages in RNA C Selvam, S Thomas, J Abbott, S Kennedy, E Rozners Angewandte Chemie (International ed. in English) 50 (9), 2068, 2011 | 59 | 2011 |
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate … F Li, PS Pallan, MA Maier, KG Rajeev, SL Mathieu, C Kreutz, Y Fan, ... Nucleic acids research 35 (19), 6424-6438, 2007 | 56 | 2007 |
Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates O Muse, T Zengeya, J Mwaura, D Hnedzko, DW McGee, CT Grewer, ... ACS chemical biology 8 (8), 1683-1686, 2013 | 55 | 2013 |
Asymmetric Synthesis of trans-3,4-Dialkyl-γ-butyrolactones via an Acyl-Claisen and Iodolactonization Route Q Xu, E Rozners Organic Letters 7 (14), 2821-2824, 2005 | 52 | 2005 |
Recent advances in chemical modification of peptide nucleic acids E Rozners Journal of nucleic acids 2012, 2012 | 48 | 2012 |
Evaluation of 2′-hydroxyl protection in RNA-synthesis using the H-phosphonate approach E Rozners, E Westman, R Strömberg Nucleic Acids Research 22 (1), 94-99, 1994 | 46 | 1994 |
Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids V Kotikam, SD Kennedy, JA MacKay, E Rozners Chemistry–A European Journal 25 (17), 4367-4372, 2019 | 42 | 2019 |