S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated … M Pende, SH Um, V Mieulet, M Sticker, VL Goss, J Mestan, M Mueller, ... Molecular and cellular biology 24 (8), 3112-3124, 2004 | 946 | 2004 |
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ... The EMBO journal 25 (12), 2781-2791, 2006 | 680 | 2006 |
Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program C Chauvin, V Koka, A Nouschi, V Mieulet, C Hoareau-Aveilla, A Dreazen, ... Oncogene 33 (4), 474-483, 2014 | 338 | 2014 |
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling GM Findlay, L Yan, J Procter, V Mieulet, RF Lamb Biochemical Journal 403 (1), 13-20, 2007 | 322 | 2007 |
miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers AM Givel, Y Kieffer, A Scholer-Dahirel, P Sirven, M Cardon, F Pelon, ... Nature communications 9 (1), 1056, 2018 | 232 | 2018 |
Heterogeneity in cancer metabolism: new concepts in an old field G Gentric, V Mieulet, F Mechta-Grigoriou Antioxidants & redox signaling 26 (9), 462-485, 2017 | 215 | 2017 |
PML-regulated mitochondrial metabolism enhances chemosensitivity in human ovarian cancers G Gentric, Y Kieffer, V Mieulet, O Goundiam, C Bonneau, F Nemati, ... Cell metabolism 29 (1), 156-173. e10, 2019 | 207 | 2019 |
Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression I Guillet-Deniau, V Mieulet, S Le Lay, Y Achouri, D Carré, J Girard, ... Diabetes 51 (6), 1722-1728, 2002 | 150 | 2002 |
PP2AT61ɛ is an inhibitor of MAP4K3 in nutrient signaling to mTOR L Yan, V Mieulet, D Burgess, GM Findlay, K Sully, J Procter, J Goris, ... Molecular cell 37 (5), 633-642, 2010 | 142 | 2010 |
Chronic oxidative stress promotes H2 AX protein degradation and enhances chemosensitivity in breast cancer patients T Gruosso, V Mieulet, M Cardon, B Bourachot, Y Kieffer, F Devun, ... EMBO molecular medicine 8 (5), 527-549, 2016 | 138 | 2016 |
S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover V Mieulet, M Roceri, C Espeillac, A Sotiropoulos, M Ohanna, V Oorschot, ... American Journal of Physiology-Cell Physiology 293 (2), C712-C722, 2007 | 122 | 2007 |
mTORC2 is the hydrophobic motif kinase for SGK1 L Yan, V Mieulet, RF Lamb Biochemical Journal 416 (3), e19-e21, 2008 | 56 | 2008 |
Tuberous sclerosis complex: linking cancer to metabolism V Mieulet, RF Lamb Trends in molecular medicine 16 (7), 329-335, 2010 | 54 | 2010 |
MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas T Gruosso, C Garnier, S Abelanet, Y Kieffer, V Lemesre, D Bellanger, ... Nature Communications 6 (1), 8583, 2015 | 52 | 2015 |
TPL-2–mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability V Mieulet, L Yan, C Choisy, K Sully, J Procter, A Kouroumalis, ... Science signaling 3 (135), ra61-ra61, 2010 | 50 | 2010 |
Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer V Mieulet, C Garnier, Y Kieffer, T Guilbert, F Nemati, E Marangoni, ... Scientific reports 11 (1), 4219, 2021 | 45 | 2021 |
Nutrient regulation of mTORC1 and cell growth L Yan, V Mieulet, RF Lamb Cell Cycle 9 (13), 2473-2474, 2010 | 9 | 2010 |
Shooting the messenger: CULLIN'insulin signaling with Fbw8 V Mieulet, RF Lamb Developmental cell 14 (6), 816-817, 2008 | 6 | 2008 |
Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells R Vivet-Noguer, M Tarin, C Canbezdi, S Dayot, L Silva, A Houy, ... Cancers 14 (9), 2113, 2022 | 5 | 2022 |
Signalling by amino acid nutrients: mTOR and beyond V Mieulet, L Yan, RF Lamb Amino Acids 37, 67-67, 2009 | 2 | 2009 |