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Sherif El Sheikh
Sherif El Sheikh
Professor für pharmazeutische Chemie, TH Köln
Verified email at th-koeln.de - Homepage
Title
Cited by
Cited by
Year
Discovery of the soluble guanylate cyclase activator runcaciguat (BAY 1101042)
MG Hahn, T Lampe, S El Sheikh, N Griebenow, E Woltering, ...
Journal of Medicinal Chemistry 64 (9), 5323-5344, 2021
412021
Preclinical antitumor efficacy of BAY 1129980—a novel auristatin-based anti-C4. 4A (LYPD3) antibody–drug conjugate for the treatment of non–small cell lung cancer
J Willuda, L Linden, HG Lerchen, C Kopitz, B Stelte-Ludwig, C Pena, ...
Molecular cancer therapeutics 16 (5), 893-904, 2017
402017
Binder-drug conjugates (ADCs) and use thereof
HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ...
US Patent 8,992,932, 2015
342015
Contemporary synthetic strategies towards secosteroids, abeo-steroids, and related triterpenes
F Noack, RC Heinze, P Heretsch
Synthesis 51 (10), 2039-2057, 2019
272019
Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions: an efficient one-step protocol applicable to microreactor technology
S Goto, J Velder, S El Sheikh, Y Sakamoto, M Mitani, S Elmas, A Adler, ...
Synlett 2008 (09), 1361-1365, 2008
242008
Synthesis of the core structure of the cyclocitrinols via SmI2-mediated fragmentation of a cyclopropane precursor
S El Sheikh, AM zu Greffen, J Lex, JM Neudörfl, HG Schmalz
Synlett 2007 (12), 1881-1884, 2007
212007
Halogen-lithium exchange reactions under in situ-quench conditions: a powerful concept for organic synthesis.
S El Sheikh, HG Schmalz
Current Opinion in Drug Discovery & Development 7 (6), 882-895, 2004
212004
Substituted 3-phenylpropionic acids and the use thereof 3
T Lampe, M Hahn, JP Stasch, KH Schlemmer, F Wunder, SS El, VMJ Li, ...
192013
New binder-drug conjugates (adcs) and use thereof
HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ...
US Patent App. 13/451,950, 2013
162013
Oxo-heterocyclic substituted carboxylic acid derivatives and the use thereof
M Hahn, EM Becker, A Knorr, D Schneider, JP Stasch, KH Schlemmer, ...
US Patent 8,987,256, 2015
122015
Oxo-heterocyclically substituted alkyl carboxylic acids and use thereof
T Lampe, M Hahn, JP Stasch, KH Schlemmer, F Wunder, S Heitmeier, ...
US Patent App. 13/201,924, 2012
122012
N-carboxyalkylauristatins and use thereof
HG Lerchen, S El Sheikh, B Stelte-Ludwig, J Schuhmacher, M Gnoth
US Patent 9,029,406, 2015
102015
N-carboxyalkyl-auristatin and the use thereof
HG Lerchen, S El Sheikh, B Stelte-Ludwig, S Golfier, J Schuhmacher, ...
US Patent 8,987,209, 2015
102015
Substituted 1-benzylcycloalkylcarboxylic acids and the use thereof
T Lampe, MG Hahn, JP Stasch, KH Schlemmer, F Wunder, S El Sheikh, ...
US Patent 9,018,258, 2015
92015
2, 4, 5-trisubstituted 1, 2, 4-triazolones useful as inhibitors of DHODH
SN Gradl, D Nguyen, K Eis, J Günther, T Stellfeld, A Janzer, S Christian, ...
US Patent 10,815,215, 2020
72020
New binder-drug conjugates (adcs) and use thereof
HG Lerchen, B Stelte-Ludwig, S Golfier, CC Kopitz, R Beier, S El Sheikh, ...
US Patent App. 13/451,916, 2013
72013
Sn(OTf)2 as an Effective Lewis Acid in Reactions of Cyclopropyl Ketones with Acetic Anhydride: Application in the Synthesis of a 19‐Nor‐B‐homo Steroid
DP Kranz, A Meier zu Greffen, S El Sheikh, JM Neudörfl, HG Schmalz
European Journal of Organic Chemistry 2011 (15), 2860-2866, 2011
72011
Novel Binder-Drug Conjugates (ADCs) and Use of Same
HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ...
US Patent App. 14/113,070, 2014
62014
2, 4, 5-Trisubstituted 1, 2, 4-triazolones useful as inhibitors of DHODH
SN Gradl, D Nguyen, K Eis, J Günther, T Stellfeld, A Janzer, S Christian, ...
US Patent 11,130,745, 2021
52021
Discovery of BAY 2402234 by phenotypic screening: A human dihydroorotate dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies
SN Gradl, T Mueller, S Ferrara, SE Sheikh, A Janzer, HJ Zhou, A Friberg, ...
Cancer Research 79 (13_Supplement), 2-2, 2019
52019
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