| Discovery of the soluble guanylate cyclase activator runcaciguat (BAY 1101042) MG Hahn, T Lampe, S El Sheikh, N Griebenow, E Woltering, ... Journal of Medicinal Chemistry 64 (9), 5323-5344, 2021 | 44 | 2021 |
| Preclinical antitumor efficacy of BAY 1129980—a novel auristatin-based anti-C4. 4A (LYPD3) antibody–drug conjugate for the treatment of non–small cell lung cancer J Willuda, L Linden, HG Lerchen, C Kopitz, B Stelte-Ludwig, C Pena, ... Molecular cancer therapeutics 16 (5), 893-904, 2017 | 44 | 2017 |
| Binder-drug conjugates (ADCs) and use thereof HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ... US Patent 8,992,932, 2015 | 34 | 2015 |
| Contemporary synthetic strategies towards secosteroids, abeo-steroids, and related triterpenes F Noack, RC Heinze, P Heretsch Synthesis 51 (10), 2039-2057, 2019 | 29 | 2019 |
| Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions: an efficient one-step protocol applicable to microreactor technology S Goto, J Velder, S El Sheikh, Y Sakamoto, M Mitani, S Elmas, A Adler, ... Synlett 2008 (09), 1361-1365, 2008 | 25 | 2008 |
| Synthesis of the core structure of the cyclocitrinols via SmI2-mediated fragmentation of a cyclopropane precursor S El Sheikh, AM zu Greffen, J Lex, JM Neudörfl, HG Schmalz Synlett 2007 (12), 1881-1884, 2007 | 22 | 2007 |
| Halogen-lithium exchange reactions under in situ-quench conditions: a powerful concept for organic synthesis. S El Sheikh, HG Schmalz Current Opinion in Drug Discovery & Development 7 (6), 882-895, 2004 | 20 | 2004 |
| Substituted 3-phenylpropionic acids and the use thereof 3 T Lampe, M Hahn, JP Stasch, KH Schlemmer, F Wunder, SS El, VMJ Li, ... | 19 | 2013 |
| New binder-drug conjugates (adcs) and use thereof HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ... US Patent App. 13/451,950, 2013 | 16 | 2013 |
| Oxo-heterocyclic substituted carboxylic acid derivatives and the use thereof M Hahn, EM Becker, A Knorr, D Schneider, JP Stasch, KH Schlemmer, ... US Patent 8,987,256, 2015 | 12 | 2015 |
| Oxo-heterocyclically substituted alkyl carboxylic acids and use thereof T Lampe, M Hahn, JP Stasch, KH Schlemmer, F Wunder, S Heitmeier, ... US Patent App. 13/201,924, 2012 | 12 | 2012 |
| N-carboxyalkylauristatins and use thereof HG Lerchen, S El Sheikh, B Stelte-Ludwig, J Schuhmacher, M Gnoth US Patent 9,029,406, 2015 | 10 | 2015 |
| N-carboxyalkyl-auristatin and the use thereof HG Lerchen, S El Sheikh, B Stelte-Ludwig, S Golfier, J Schuhmacher, ... US Patent 8,987,209, 2015 | 10 | 2015 |
| Substituted 1-benzylcycloalkylcarboxylic acids and the use thereof T Lampe, MG Hahn, JP Stasch, KH Schlemmer, F Wunder, S El Sheikh, ... US Patent 9,018,258, 2015 | 9 | 2015 |
| 2, 4, 5-trisubstituted 1, 2, 4-triazolones useful as inhibitors of DHODH SN Gradl, D Nguyen, K Eis, J Günther, T Stellfeld, A Janzer, S Christian, ... US Patent 10,815,215, 2020 | 7 | 2020 |
| New binder-drug conjugates (adcs) and use thereof HG Lerchen, B Stelte-Ludwig, S Golfier, CC Kopitz, R Beier, S El Sheikh, ... US Patent App. 13/451,916, 2013 | 7 | 2013 |
| Sn(OTf)2 as an Effective Lewis Acid in Reactions of Cyclopropyl Ketones with Acetic Anhydride: Application in the Synthesis of a 19‐Nor‐B‐homo Steroid DP Kranz, A Meier zu Greffen, S El Sheikh, JM Neudörfl, HG Schmalz European Journal of Organic Chemistry 2011 (15), 2860-2866, 2011 | 7 | 2011 |
| Novel Binder-Drug Conjugates (ADCs) and Use of Same HG Lerchen, L Linden, S El Sheikh, J Willuda, CC Kopitz, J Schuhmacher, ... US Patent App. 14/113,070, 2014 | 6 | 2014 |
| 2, 4, 5-Trisubstituted 1, 2, 4-triazolones useful as inhibitors of DHODH SN Gradl, D Nguyen, K Eis, J Günther, T Stellfeld, A Janzer, S Christian, ... US Patent 11,130,745, 2021 | 5 | 2021 |
| Discovery of BAY 2402234 by phenotypic screening: A human dihydroorotate dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies SN Gradl, T Mueller, S Ferrara, SE Sheikh, A Janzer, HJ Zhou, A Friberg, ... Cancer Research 79 (13_Supplement), 2-2, 2019 | 5 | 2019 |
