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Tom H Wright
Tom H Wright
Harvard/ MGH
Verified email at molbio.mgh.harvard.edu
Title
Cited by
Cited by
Year
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, ...
Science 354 (6312), aag1465, 2016
2672016
Light-driven post-translational installation of reactive protein side chains
B Josephson, C Fehl, PG Isenegger, S Nadal, TH Wright, AWJ Poh, ...
Nature 585 (7826), 530-537, 2020
1112020
Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates.
TH Wright, AE Brooks, AJ Didsbury, JD MacIntosh, GM Williams, ...
Angewandte Chemie (International ed. in English) 52 (40), 10616-10619, 2013
792013
Non-enzymatic primer extension with strand displacement
L Zhou, SC Kim, KH Ho, DK O'Flaherty, C Giurgiu, TH Wright, JW Szostak
Elife 8, e51888, 2019
472019
Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity
Z Amso, SW Bisset, SH Yang, PWR Harris, TH Wright, CD Navo, ...
Chemical science 9 (6), 1686-1691, 2018
472018
Synthesis of the antimicrobial S‐linked glycopeptide, Glycocin F
MA Brimble, PJ Edwards, PWR Harris, GE Norris, ML Patchett, TH Wright, ...
Chemistry–A European Journal 21 (9), 3556-3561, 2015
402015
Synthesis and biological evaluation of novel teixobactin analogues
CE Schumacher, PWR Harris, XB Ding, B Krause, TH Wright, GM Cook, ...
Organic & biomolecular chemistry 15 (41), 8755-8760, 2017
392017
From chemical mutagenesis to post‐expression mutagenesis: a 50 year odyssey
TH Wright, MRJ Vallée, BG Davis
Angewandte Chemie International Edition 55 (20), 5896-5903, 2016
372016
Post-translational mutagenesis for installation of natural and unnatural amino acid side chains into recombinant proteins
TH Wright, BG Davis
nature protocols 12 (10), 2243-2250, 2017
292017
Prebiotically plausible “patching” of RNA backbone cleavage through a 3′–5′ pyrophosphate linkage
TH Wright, C Giurgiu, W Zhang, A Radakovic, DK O’Flaherty, L Zhou, ...
Journal of the American Chemical Society 141 (45), 18104-18112, 2019
202019
A Fluorescent G‐quadruplex Sensor for Chemical RNA Copying
C Giurgiu, T Wright, D O'Flaherty, J Szostak
Angewandte Chemie, 2018
132018
Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides
A Radakovic, S DasGupta, TH Wright, HRM Aitken, JW Szostak
Proceedings of the National Academy of Sciences 119 (7), e2116840119, 2022
112022
A synthetic approach to ‘click’neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry
DJ Lee, AJ Cameron, TH Wright, PWR Harris, MA Brimble
Chemical Science 10 (3), 815-828, 2019
102019
An improved method for the synthesis of lipopeptide TLR2-agonists using click chemistry
TH Wright, AES Brooks, AJ Didsbury, JD McIntosh, K Burkert, H Yeung, ...
Synlett 24 (14), 1835-1841, 2013
92013
A potential role for aminoacylation in primordial RNA copying chemistry
A Radakovic, TH Wright, VS Lelyveld, JW Szostak
Biochemistry 60 (6), 477-488, 2021
62021
Incorporation of ‘click’chemistry glycomimetics dramatically alters triple-helix stability in an adiponectin model peptide
KR Lutteroth, PWR Harris, TH Wright, H Kaur, K Sparrow, SH Yang, ...
Organic & biomolecular chemistry 15 (26), 5602-5608, 2017
62017
Small-Molecule Organocatalysis Facilitates In Situ Nucleotide Activation and RNA Copying
HRM Aitken, TH Wright, A Radakovic, JW Szostak
Journal of the American Chemical Society 145 (29), 16142-16149, 2023
52023
Amino acid and peptide conjugates and conjugation process
MA Brimble, TH Wright, PR Dunbar, GM Williams
US Patent 10,576,144, 2020
52020
Amino acid and peptide conjugates and conjugation process
MA Brimble, TH WRIGHT, RP DUNBAR, GM Williams
22014
Amino acid and peptide conjugates and conjugation process
MA Brimble, TH Wright, PR Dunbar, GM Williams
US Patent App. 16/773,241, 2020
2020
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