| Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ... Science 344 (6190), 1396-1401, 2014 | 1792 | 2014 |
| Insulator dysfunction and oncogene activation in IDH mutant gliomas WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ... Nature 529 (7584), 110-114, 2016 | 561 | 2016 |
| Epigenetic reprogramming in cancer ML Suvā, N Riggi, BE Bernstein Science 339 (6127), 1567-1570, 2013 | 553 | 2013 |
| Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells ML Suvā, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ... Cell 157 (3), 580-594, 2014 | 494 | 2014 |
| EZH2 is essential for glioblastoma cancer stem cell maintenance ML Suvā, N Riggi, M Janiszewska, I Radovanovic, P Provero, JC Stehle, ... Cancer research 69 (24), 9211-9218, 2009 | 412 | 2009 |
| Development of Ewing's sarcoma from primary bone marrow–derived mesenchymal progenitor cells N Riggi, L Cironi, P Provero, ML Suvā, K Kaloulis, C Garcia-Echeverria, ... Cancer research 65 (24), 11459-11468, 2005 | 362 | 2005 |
| Malarial hemozoin is a Nalp3 inflammasome activating danger signal C Dostert, G Guarda, JF Romero, P Menu, O Gross, A Tardivel, ML Suva, ... PloS one 4 (8), 2009 | 356 | 2009 |
| Identification of cancer stem cells in Ewing's sarcoma ML Suvā, N Riggi, JC Stehle, K Baumer, S Tercier, JM Joseph, D Suvā, ... Cancer research 69 (5), 1776-1781, 2009 | 320 | 2009 |
| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 319 | 2016 |
| EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells N Riggi, ML Suvā, D Suvā, L Cironi, P Provero, S Tercier, JM Joseph, ... Cancer research 68 (7), 2176-2185, 2008 | 303 | 2008 |
| Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ... Science 347 (6219), 273-277, 2015 | 258 | 2015 |
| EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells N Riggi, ML Suvā, C De Vito, P Provero, JC Stehle, K Baumer, L Cironi, ... Genes & development 24 (9), 916-932, 2010 | 251 | 2010 |
| Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), eaai8478, 2017 | 243 | 2017 |
| Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells M Janiszewska, ML Suvā, N Riggi, RH Houtkooper, J Auwerx, ... Genes & development 26 (17), 1926-1944, 2012 | 214 | 2012 |
| An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma E Rheinbay, ML Suvā, SM Gillespie, H Wakimoto, AP Patel, M Shahid, ... Cell reports 3 (5), 1567-1579, 2013 | 188 | 2013 |
| EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma N Riggi, B Knoechel, SM Gillespie, E Rheinbay, G Boulay, ML Suvā, ... Cancer cell 26 (5), 668-681, 2014 | 167 | 2014 |
| Sarcomas: genetics, signalling, and cellular origins. Part 1: The fellowship of TET N Riggi, L Cironi, ML Suvā, I Stamenkovic The Journal of pathology 213 (1), 4-20, 2007 | 142 | 2007 |
| Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma N Riggi, L Cironi, P Provero, ML Suvā, JC Stehle, K Baumer, L Guillou, ... Cancer Research 66 (14), 7016-7023, 2006 | 140 | 2006 |
| Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ... Nature 565 (7738), 234-239, 2019 | 124 | 2019 |
| Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 114 | 2018 |
Bradley BernsteinProfessor of Pathology, Harvard UniversityVerified email at broadinstitute.org
