| Functional roles of N‐glycans in cell signaling and cell adhesion in cancer YY Zhao, M Takahashi, JG Gu, E Miyoshi, A Matsumoto, S Kitazume, ... Cancer science 99 (7), 1304-1310, 2008 | 482 | 2008 |
| Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase S Kitazume, Y Tachida, R Oka, K Shirotani, TC Saido, Y Hashimoto Proceedings of the National Academy of Sciences 98 (24), 13554-13559, 2001 | 363 | 2001 |
| An aberrant sugar modification of BACE 1 blocks its lysosomal targeting in A lzheimer's disease Y Kizuka, S Kitazume, R Fujinawa, T Saito, N Iwata, TC Saido, M Nakano, ... EMBO molecular medicine 7 (2), 175-189, 2015 | 174 | 2015 |
| Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC K Nakajima, S Kitazume, T Angata, R Fujinawa, K Ohtsubo, E Miyoshi, ... Glycobiology 20 (7), 865-871, 2010 | 155 | 2010 |
| Characterization of α2, 6-sialyltransferase cleavage by Alzheimer's β-secretase (BACE1) S Kitazume, Y Tachida, R Oka, N Kotani, K Ogawa, M Suzuki, N Dohmae, ... Journal of Biological Chemistry 278 (17), 14865-14871, 2003 | 141 | 2003 |
| α2, 6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling S Kitazume, R Imamaki, K Ogawa, Y Komi, S Futakawa, S Kojima, ... Journal of biological chemistry 285 (9), 6515-6521, 2010 | 125 | 2010 |
| N-glycan and Alzheimer's disease Y Kizuka, S Kitazume, N Taniguchi Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (10), 2447-2454, 2017 | 124 | 2017 |
| In vivo cleavage of α2, 6-sialyltransferase by Alzheimer β-secretase S Kitazume, K Nakagawa, R Oka, Y Tachida, K Ogawa, Y Luo, M Citron, ... Journal of Biological Chemistry 280 (9), 8589-8595, 2005 | 121 | 2005 |
| Brain endothelial cells produce amyloid β from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form S Kitazume, Y Tachida, M Kato, Y Yamaguchi, T Honda, Y Hashimoto, ... Journal of biological chemistry 285 (51), 40097-40103, 2010 | 114 | 2010 |
| Interleukin‐1β up‐regulates TACE to enhance α‐cleavage of APP in neurons: Resulting decrease in Aβ production Y Tachida, K Nakagawa, T Saito, TC Saido, T Honda, Y Saito, ... Journal of neurochemistry 104 (5), 1387-1393, 2008 | 114 | 2008 |
| A single dose of lipopolysaccharide into mice with emphysema mimics human chronic obstructive pulmonary disease exacerbation as assessed by micro-computed tomography S Kobayashi, R Fujinawa, F Ota, S Kobayashi, T Angata, M Ueno, ... American journal of respiratory cell and molecular biology 49 (6), 971-977, 2013 | 107 | 2013 |
| KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine T Kimura, D Shuto, S Kasai, P Liu, K Hidaka, T Hamada, Y Hayashi, ... Bioorganic & medicinal chemistry letters 14 (6), 1527-1531, 2004 | 93 | 2004 |
| Molecular cloning and functional expression of two members of mouse NeuAcα2, 3Galβ1, 3GalNAc GalNAcα2, 6-sialyltransferase family, ST6GalNAc III and IV YC Lee, M Kaufmann, S Kitazume-Kawaguchi, M Kono, S Takashima, ... Journal of Biological Chemistry 274 (17), 11958-11967, 1999 | 92 | 1999 |
| Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation T Angata, T Ishii, T Motegi, R Oka, RE Taylor, PC Soto, YC Chang, ... Cellular and molecular life sciences 70, 3199-3210, 2013 | 90 | 2013 |
| Sialylation enhances the secretion of neurotoxic amyloid‐β peptides K Nakagawa, S Kitazume, R Oka, K Maruyama, TC Saido, Y Sato, T Endo, ... Journal of neurochemistry 96 (4), 924-933, 2006 | 89 | 2006 |
| Differential biosynthesis of polysialic or disialic acid structure by ST8Sia II and ST8Sia IV S Kitazume-Kawaguchi, S Kabata, M Arita Journal of Biological Chemistry 276 (19), 15696-15703, 2001 | 88 | 2001 |
| Isolation and identification of novel sulfated and nonsulfated oligosialyl glycosphingolipids from sea urchin sperm T Ijuin, K Kitajima, Y Song, S Kitazume, S Inoue, SM Haslam, HR Morris, ... Glycoconjugate journal 13, 401-413, 1996 | 84 | 1996 |
| Identification of polysialic acid-containing glycoprotein in the jelly coat of sea urchin eggs. Occurrence of a novel type of polysialic acid structure. S Kitazume, K Kitajima, S Inoue, FA Troy, JW Cho, WJ Lennarz, Y Inoue Journal of Biological Chemistry 269 (36), 22712-22718, 1994 | 82 | 1994 |
| Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions Y Kizuka, M Nakano, S Kitazume, T Saito, TC Saido, N Taniguchi Biochemical Journal 473 (1), 21-30, 2016 | 78 | 2016 |
| Detection, isolation, and characterization of oligo/poly (sialic acid) and oligo/poly (deaminoneuraminic acid) units in glycoconjugates S Kitazume, K Kitajima, S Inoue, Y Inoue Analytical biochemistry 202 (1), 25-34, 1992 | 76 | 1992 |
