| Siglec-mediated regulation of immune cell function in disease MS Macauley, PR Crocker, JC Paulson Nature Reviews Immunology 14 (10), 653-666, 2014 | 1005 | 2014 |
| A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo SA Yuzwa, MS Macauley, JE Heinonen, X Shan, RJ Dennis, Y He, ... Nature chemical biology 4 (8), 483-490, 2008 | 767 | 2008 |
| Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation SA Yuzwa, X Shan, MS Macauley, T Clark, Y Skorobogatko, K Vosseller, ... Nature chemical biology 8 (4), 393-399, 2012 | 600 | 2012 |
| O-GlcNAcase Uses Substrate-assisted Catalysis: KINETICANALYSIS AND DEVELOPMENT OF HIGHLY SELECTIVE MECHANISM-INSPIREDINHIBITORS MS Macauley, GE Whitworth, AW Debowski, D Chin, DJ Vocadlo Journal of Biological Chemistry 280 (27), 25313-25322, 2005 | 460 | 2005 |
| Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc) DAR Sinclair, M Syrzycka, MS Macauley, T Rastgardani, I Komljenovic, ... Proceedings of the National Academy of Sciences 106 (32), 13427-13432, 2009 | 250 | 2009 |
| Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity RJ Dennis, EJ Taylor, MS Macauley, KA Stubbs, JP Turkenburg, SJ Hart, ... Nature structural & molecular biology 13 (4), 365-371, 2006 | 244 | 2006 |
| Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies LE McCoy, MJ van Gils, G Ozorowski, T Messmer, B Briney, JE Voss, ... Cell reports 16 (9), 2327-2338, 2016 | 231 | 2016 |
| Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis MS Macauley, F Pfrengle, C Rademacher, CM Nycholat, AJ Gale, ... The Journal of clinical investigation 123 (7), 3074-3083, 2013 | 228 | 2013 |
| Transfection of microRNA mimics should be used with caution HY Jin, A Gonzalez-Martin, AV Miletic, M Lai, S Knight, M Sabouri-Ghomi, ... Frontiers in genetics 6, 154707, 2015 | 205 | 2015 |
| Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase: Mechanistic and Structural Insights into Inhibitor Selectivity and … GE Whitworth, MS Macauley, KA Stubbs, RJ Dennis, EJ Taylor, GJ Davies, ... Journal of the American Chemical Society 129 (3), 635-644, 2007 | 194 | 2007 |
| Hypersialylation in cancer: modulation of inflammation and therapeutic opportunities E Rodrigues, MS Macauley Cancers 10 (6), 207, 2018 | 176 | 2018 |
| Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2 L Nguyen, KA McCord, DT Bui, KM Bouwman, EN Kitova, M Elaish, ... Nature Chemical Biology 18 (1), 81-90, 2022 | 155 | 2022 |
| Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing M Lee, H Kiefel, MD LaJevic, MS Macauley, H Kawashima, E O'Hara, ... Nature immunology 15 (10), 982-995, 2014 | 152 | 2014 |
| Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance MS Macauley, AK Bubb, C Martinez-Fleites, GJ Davies, DJ Vocadlo Journal of biological chemistry 283 (50), 34687-34695, 2008 | 143 | 2008 |
| Identification of Asp174 and Asp175 as the Key Catalytic Residues of Human O-GlcNAcase by Functional Analysis of Site-Directed Mutants N Çetinbaş, MS Macauley, KA Stubbs, R Drapala, DJ Vocadlo Biochemistry 45 (11), 3835-3844, 2006 | 139 | 2006 |
| Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase MS Macauley, DJ Vocadlo Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (2), 107-121, 2010 | 136 | 2010 |
| Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation C Martinez-Fleites, MS Macauley, Y He, DL Shen, DJ Vocadlo, GJ Davies Nature structural & molecular biology 15 (7), 764-765, 2008 | 136 | 2008 |
| Targeting selectins and their ligands in cancer A Natoni, MS Macauley, ME O’Dwyer Frontiers in oncology 6, 93, 2016 | 126 | 2016 |
| Streptococcus pneumoniae endohexosaminidase D, structural and mechanistic insight into substrate-assisted catalysis in family 85 glycoside hydrolases DW Abbott, MS Macauley, DJ Vocadlo, AB Boraston Journal of biological chemistry 284 (17), 11676-11689, 2009 | 124 | 2009 |
| Tools for studying glycans: recent advances in chemoenzymatic glycan labeling A Lopez Aguilar, JG Briard, L Yang, B Ovryn, MS Macauley, P Wu ACS chemical biology 12 (3), 611-621, 2017 | 109 | 2017 |
James PaulsonThe Scripps Research InstituteVerified email at scripps.edu
