| Exosome-mediated delivery of hydrophobically modified siRNA for huntingtin mRNA silencing MC Didiot, LM Hall, AH Coles, RA Haraszti, BMDC Godinho, K Chase, ... Molecular Therapy 24 (10), 1836-1847, 2016 | 451 | 2016 |
| Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue H Liang, Q Chen, AH Coles, SJ Anderson, G Pihan, A Bradley, R Gerstein, ... Cancer cell 4 (5), 349-360, 2003 | 411 | 2003 |
| Exosomes produced from 3D cultures of MSCs by tangential flow filtration show higher yield and improved activity RA Haraszti, R Miller, M Stoppato, YY Sere, A Coles, MC Didiot, ... Molecular Therapy 26 (12), 2838-2847, 2018 | 355 | 2018 |
| RNAi modulation of placental sFLT1 for the treatment of preeclampsia AA Turanov, A Lo, MR Hassler, A Makris, A Ashar-Patel, JF Alterman, ... Nature biotechnology 36 (12), 1164-1173, 2018 | 160 | 2018 |
| A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system JF Alterman, BMDC Godinho, MR Hassler, CM Ferguson, D Echeverria, ... Nature biotechnology 37 (8), 884-894, 2019 | 153 | 2019 |
| Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo MR Hassler, AA Turanov, JF Alterman, RA Haraszti, AH Coles, MF Osborn, ... Nucleic acids research 46 (5), 2185-2196, 2018 | 150 | 2018 |
| Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo A Biscans, A Coles, R Haraszti, D Echeverria, M Hassler, M Osborn, ... Nucleic acids research 47 (3), 1082-1096, 2019 | 149 | 2019 |
| Hydrophobically modified siRNAs silence huntingtin mRNA in primary neurons and mouse brain JF Alterman, LM Hall, AH Coles, MR Hassler, MC Didiot, K Chase, ... Molecular Therapy-Nucleic Acids 4, 2015 | 147 | 2015 |
| The ING gene family in the regulation of cell growth and tumorigenesis AH Coles, SN Jones Journal of cellular physiology 218 (1), 45-57, 2009 | 129 | 2009 |
| Mutation of the SNF2 family member Chd2 affects mouse development and survival CGA Marfella, Y Ohkawa, AH Coles, DS Garlick, SN Jones, AN Imbalzano Journal of cellular physiology 209 (1), 162-171, 2006 | 113 | 2006 |
| Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways MF Osborn, AH Coles, A Biscans, RA Haraszti, L Roux, S Davis, S Ly, ... Nucleic acids research 47 (3), 1070-1081, 2019 | 112 | 2019 |
| Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis AH Coles, H Liang, Z Zhu, CGA Marfella, J Kang, AN Imbalzano, ... Cancer research 67 (5), 2054-2061, 2007 | 106 | 2007 |
| 5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo RA Haraszti, L Roux, AH Coles, AA Turanov, JF Alterman, D Echeverria, ... Nucleic acids research 45 (13), 7581-7592, 2017 | 100 | 2017 |
| Docosahexaenoic acid conjugation enhances distribution and safety of siRNA upon local administration in mouse brain M Nikan, MF Osborn, AH Coles, BMDC Godinho, LM Hall, RA Haraszti, ... Molecular Therapy-Nucleic Acids 5, 2016 | 85 | 2016 |
| Magnitude of and prognostic factors associated with 1‐year mortality after hospital discharge for acute decompensated heart failure based on ejection fraction findings AH Coles, M Tisminetzky, J Yarzebski, D Lessard, JM Gore, CE Darling, ... Journal of the American Heart Association 4 (12), e002303, 2015 | 79 | 2015 |
| Hdac6 regulates Tip60-p400 function in stem cells PB Chen, JH Hung, TL Hickman, AH Coles, JF Carey, Z Weng, F Chu, ... Elife 2, e01557, 2013 | 78 | 2013 |
| Noncanonical Wnt signaling promotes apoptosis in thymocyte development H Liang, AH Coles, Z Zhu, J Zayas, R Jurecic, J Kang, SN Jones The Journal of experimental medicine 204 (13), 3077-3084, 2007 | 78 | 2007 |
| Serum deprivation of mesenchymal stem cells improves exosome activity and alters lipid and protein composition RA Haraszti, R Miller, ML Dubuke, HE Rockwell, AH Coles, E Sapp, ... Iscience 16, 230-241, 2019 | 74 | 2019 |
| Inhibitor of growth-4 promotes IκB promoter activation to suppress NF-κB signaling and innate immunity AH Coles, H Gannon, A Cerny, E Kurt-Jones, SN Jones Proceedings of the National Academy of Sciences 107 (25), 11423-11428, 2010 | 67 | 2010 |
| The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo A Biscans, A Coles, D Echeverria, A Khvorova Journal of controlled release 302, 116-125, 2019 | 53 | 2019 |
