| Generalized simulated annealing for global optimization: the GenSA package. Y Xiang, S Gubian, B Suomela, J Hoeng R J. 5 (1), 13, 2013 | 402 | 2013 |
| Generalized simulated annealing algorithm and its application to the Thomson model Y Xiang, DY Sun, W Fan, XG Gong Physics Letters A 233 (3), 216-220, 1997 | 259 | 1997 |
| Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers C Mathis, C Poussin, D Weisensee, S Gebel, A Hengstermann, A Sewer, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 304 (7 …, 2013 | 160 | 2013 |
| Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge AL Tarca, M Lauria, M Unger, E Bilal, S Boue, K Kumar Dey, J Hoeng, ... Bioinformatics 29 (22), 2892-2899, 2013 | 131 | 2013 |
| Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by … B Phillips, B Titz, U Kogel, D Sharma, P Leroy, Y Xiang, G Vuillaume, ... Food and chemical toxicology 109, 315-332, 2017 | 128 | 2017 |
| Efficiency of generalized simulated annealing Y Xiang, XG Gong Physical Review E 62 (3), 4473, 2000 | 126 | 2000 |
| Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models F Martin, A Sewer, M Talikka, Y Xiang, J Hoeng, MC Peitsch BMC bioinformatics 15, 1-24, 2014 | 112 | 2014 |
| Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with … ET Wong, U Kogel, E Veljkovic, F Martin, Y Xiang, S Boue, G Vuillaume, ... Regulatory Toxicology and Pharmacology 81, S59-S81, 2016 | 92 | 2016 |
| A framework for in vitro systems toxicology assessment of e-liquids AR Iskandar, I Gonzalez-Suarez, S Majeed, D Marescotti, A Sewer, ... Toxicology Mechanisms and Methods 26 (6), 392-416, 2016 | 91 | 2016 |
| Generalized Simulated Annealing Studies on Structures and Properties of Nin (n = 2−55) Clusters Y Xiang, DY Sun, XG Gong The Journal of Physical Chemistry A 104 (12), 2746-2751, 2000 | 83 | 2000 |
| A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared … U Kogel, WK Schlage, F Martin, Y Xiang, S Ansari, P Leroy, ... Food and chemical toxicology 68, 204-217, 2014 | 81 | 2014 |
| Case study: the role of mechanistic network models in systems toxicology J Hoeng, M Talikka, F Martin, A Sewer, X Yang, A Iskandar, WK Schlage, ... Drug Discovery Today 19 (2), 183-192, 2014 | 78 | 2014 |
| 3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product AR Iskandar, C Mathis, F Martin, P Leroy, A Sewer, S Majeed, D Kuehn, ... ALTEX-Alternatives to animal experimentation 34 (1), 23-48, 2017 | 68 | 2017 |
| A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human … AR Iskandar, C Mathis, WK Schlage, S Frentzel, P Leroy, Y Xiang, ... Toxicology in vitro 39, 29-51, 2017 | 63 | 2017 |
| Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: a comparison of mono-culture and coculture model containing fibroblasts AR Iskandar, Y Xiang, S Frentzel, M Talikka, P Leroy, D Kuehn, E Guedj, ... Toxicological Sciences 147 (1), 207-221, 2015 | 61 | 2015 |
| In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue … WK Schlage, AR Iskandar, R Kostadinova, Y Xiang, A Sewer, S Majeed, ... Toxicology mechanisms and methods 24 (7), 470-487, 2014 | 60 | 2014 |
| Evaluation of the Tobacco Heating System 2.2 (THS2. 2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2. 2 aerosol causes reduced … A Sewer, U Kogel, M Talikka, ET Wong, F Martin, Y Xiang, E Guedj, ... Regulatory toxicology and pharmacology 81, S82-S92, 2016 | 51 | 2016 |
| Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells U Kogel, IG Suarez, Y Xiang, E Dossin, PA Guy, C Mathis, D Marescotti, ... Toxicology in Vitro 29 (8), 2102-2115, 2015 | 43 | 2015 |
| The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure M Talikka, R Kostadinova, Y Xiang, C Mathis, A Sewer, S Majeed, ... International Journal of Toxicology 33 (6), 506-517, 2014 | 42 | 2014 |
| A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke J Szostak, ET Wong, B Titz, T Lee, SK Wong, T Low, KM Lee, J Zhang, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (3 …, 2020 | 40 | 2020 |
Patrice LeroyStatistician, Philip Morris InternationalBestätigte E-Mail-Adresse bei pmi.com
