Jacqueline A Lees
Jacqueline A Lees
Koch Institute of Integrative Cancer Research @ MIT
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Cited by
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Sibling rivalry in the E2F family
JM Trimarchi, JA Lees
Nature reviews Molecular cell biology 3 (1), 11-20, 2002
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
GL Mutter, MC Lin, JT Fitzgerald, JB Kum, JPA Baak, JA Lees, LP Weng, ...
Journal of the national cancer institute 92 (11), 924-930, 2000
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.
PS Danielian, R White, JA Lees, MG Parker
The EMBO journal 11 (3), 1025-1033, 1992
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
K Helin, JA Lees, M Vidal, N Dyson, E Harlow, A Fattaey
Cell 70 (2), 337-350, 1992
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
SE Fawell, JA Lees, R White, MG Parker
Cell 60 (6), 953-962, 1990
p53-deficient cells rely on ATM-and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
HC Reinhardt, AS Aslanian, JA Lees, MB Yaffe
Cancer cell 11 (2), 175-189, 2007
The retinoblastoma protein binds to a family of E2F transcription factors
JA Lees, M Saito, M Vidal, M Valentine, T Look, E Harlow, N Dyson, ...
Molecular and cellular biology, 1993
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.
K Helin, CL Wu, AR Fattaey, JA Lees, BD Dynlacht, C Ngwu, E Harlow
Genes & development 7 (10), 1850-1861, 1993
Differential regulation of E2F transactivation by cyclin/cdk2 complexes.
BD Dynlacht, O Flores, JA Lees, E Harlow
Genes & development 8 (15), 1772-1786, 1994
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
A Perren, LP Weng, AH Boag, U Ziebold, K Thakore, PLM Dahia, ...
The American journal of pathology 155 (4), 1253-1260, 1999
Many ribosomal protein genes are cancer genes in zebrafish
A Amsterdam, KC Sadler, K Lai, S Farrington, RT Bronson, JA Lees, ...
PLoS biology 2 (5), e139, 2004
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
K Moberg, MA Starz, JA Lees
Molecular and cellular biology, 1996
Structural organization and expression of the mouse estrogen receptor
R White, JA Lees, M Needham, J Ham, M Parker
Molecular Endocrinology 1 (10), 735-744, 1987
E2f3 is critical for normal cellular proliferation
PO Humbert, R Verona, JM Trimarchi, C Rogers, S Dandapani, JA Lees
Genes & development 14 (6), 690-703, 2000
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors
O Gimm, A Perren, LP Weng, DJ Marsh, JJ Yeh, U Ziebold, E Gil, R Hinze, ...
The American journal of pathology 156 (5), 1693-1700, 2000
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.
JA Lees, KJ Buchkovich, DR Marshak, CW Anderson, E Harlow
The EMBO journal 10 (13), 4279-4290, 1991
Identification of two transactlvation domains in the mouse oestrogen receptor
JA Lees, SE Fawell, MG Parker
Nucleic acids research 17 (14), 5477-5488, 1989
Single-molecule transcript counting of stem-cell markers in the mouse intestine
S Itzkovitz, A Lyubimova, IC Blat, M Maynard, J Van Es, J Lees, T Jacks, ...
Nature cell biology 14 (1), 106-114, 2012
PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death
LP Weng, WM Smith, PLM Dahia, U Ziebold, E Gil, JA Lees, C Eng
Cancer research 59 (22), 5808-5814, 1999
E2Fs regulate adipocyte differentiation
L Fajas, RL Landsberg, Y Huss-Garcia, C Sardet, JA Lees, J Auwerx
Developmental cell 3 (1), 39-49, 2002
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