Whole-genome association study identifies STK39 as a hypertension susceptibility gene Y Wang, JR O'Connell, PF McArdle, JB Wade, SE Dorff, SJ Shah, X Shi, ... Proceedings of the National Academy of Sciences 106 (1), 226-231, 2009 | 352 | 2009 |
Distal convoluted tubule AR Subramanya, DH Ellison Clinical Journal of the American Society of Nephrology 9 (12), 2147-2163, 2014 | 299 | 2014 |
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport CL Yang, X Zhu, Z Wang, AR Subramanya, DH Ellison The Journal of clinical investigation 115 (5), 1379-1387, 2005 | 213 | 2005 |
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway DJ Rozansky, T Cornwall, AR Subramanya, S Rogers, YF Yang, LL David, ... The Journal of clinical investigation 119 (9), 2601-2612, 2009 | 170 | 2009 |
WNK1 kinase isoform switch regulates renal potassium excretion JB Wade, L Fang, J Liu, D Li, CL Yang, AR Subramanya, D Maouyo, ... Proceedings of the National Academy of Sciences 103 (22), 8558-8563, 2006 | 145 | 2006 |
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction AR Subramanya, J Liu, DH Ellison, JB Wade, PA Welling Journal of biological chemistry 284 (27), 18471-18480, 2009 | 136 | 2009 |
Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform AR Subramanya, CL Yang, X Zhu, DH Ellison American Journal of Physiology-Renal Physiology 290 (3), F619-F624, 2006 | 134 | 2006 |
WNK kinases influence TRPV4 channel function and localization Y Fu, A Subramanya, D Rozansky, DM Cohen American Journal of Physiology-Renal Physiology 290 (6), F1305-F1314, 2006 | 109 | 2006 |
WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron AR Subramanya, CL Yang, JA McCormick, DH Ellison Kidney international 70 (4), 630-634, 2006 | 103 | 2006 |
Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action A Roy, L Al-Qusairi, BF Donnelly, C Ronzaud, AL Marciszyn, F Gong, ... The Journal of clinical investigation 125 (9), 3433-3448, 2015 | 69 | 2015 |
WNK kinases sense molecular crowding and rescue cell volume via phase separation CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ... Cell 185 (24), 4488-4506. e20, 2022 | 67 | 2022 |
Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis BF Donnelly, PG Needham, AC Snyder, A Roy, S Khadem, JL Brodsky, ... Journal of Biological Chemistry 288 (18), 13124-13135, 2013 | 63 | 2013 |
Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent CR Boyd-Shiwarski, DJ Shiwarski, A Roy, HN Namboodiri, LJ Nkashama, ... Molecular biology of the cell 29 (4), 499-509, 2018 | 62 | 2018 |
Endothelial-derived vasoactive mediators in polycystic kidney disease MA Al-Nimri, R Komers, TT Oyama, AR Subramanya, JN Lindsley, ... Kidney international 63 (5), 1776-1784, 2003 | 62 | 2003 |
The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel TM Buck, L Plavchak, A Roy, BF Donnelly, OB Kashlan, TR Kleyman, ... Journal of Biological Chemistry 288 (25), 18366-18380, 2013 | 60 | 2013 |
The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation PG Needham, K Mikoluk, P Dhakarwal, S Khadem, AC Snyder, ... Journal of Biological Chemistry 286 (51), 43611-43621, 2011 | 56 | 2011 |
Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing A Roy, JH Goodman, G Begum, BF Donnelly, G Pittman, EJ Weinman, ... American Journal of Physiology-Renal Physiology 308 (4), F366-F376, 2015 | 50 | 2015 |
Endoplasmic reticulum–associated degradation of the renal potassium channel, ROMK, leads to type II Bartter syndrome BM O'Donnell, TD Mackie, AR Subramanya, JL Brodsky Journal of Biological Chemistry 292 (31), 12813-12827, 2017 | 41 | 2017 |
Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC L Al-Qusairi, D Basquin, A Roy, M Stifanelli, RD Rajaram, A Debonneville, ... American Journal of Physiology-Renal Physiology 311 (2), F330-F342, 2016 | 39 | 2016 |
Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase Z Wang, AR Subramanya, LM Satlin, NM Pastor-Soler, MD Carattino, ... American Journal of Physiology-Cell Physiology 305 (8), C846-C853, 2013 | 38 | 2013 |