Jan Mauer, Ph.D.
Jan Mauer, Ph.D.
Group Leader at BioMed X Innovation Center
Bestätigte E-Mail-Adresse bei bio.mx - Startseite
TitelZitiert vonJahr
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
A Kleinridders, D Schenten, AC Könner, BF Belgardt, J Mauer, T Okamura, ...
Cell metabolism 10 (4), 249-259, 2009
3942009
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
J Mauer, B Chaurasia, J Goldau, MC Vogt, J Ruud, KD Nguyen, ...
Nature immunology 15 (5), 423, 2014
3622014
Obesity-induced CerS6-dependent C16: 0 ceramide production promotes weight gain and glucose intolerance
SM Turpin, HT Nicholls, DM Willmes, A Mourier, S Brodesser, ...
Cell metabolism 20 (4), 678-686, 2014
2472014
Reversible methylation of m6Am in the 5′ cap controls mRNA stability
J Mauer, X Luo, A Blanjoie, X Jiao, AV Grozhik, DP Patil, B Linder, ...
Nature 541 (7637), 371, 2017
2322017
Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding
MC Vogt, L Paeger, S Hess, SM Steculorum, M Awazawa, B Hampel, ...
Cell 156 (3), 495-509, 2014
1822014
Versatile functions for IL-6 in metabolism and cancer
J Mauer, JL Denson, JC Brüning
Trends in immunology 36 (2), 92-101, 2015
1552015
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
BF Belgardt, J Mauer, FT Wunderlich, MB Ernst, M Pal, G Spohn, ...
Proceedings of the National Academy of Sciences 107 (13), 6028-6033, 2010
1392010
Single copy shRNA configuration for ubiquitous gene knockdown in mice
J Seibler, B Küter-Luks, H Kern, S Streu, L Plum, J Mauer, R Kühn, ...
Nucleic acids research 33 (7), e67-e67, 2005
1232005
AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue
SM Steculorum, J Ruud, I Karakasilioti, H Backes, LE Ruud, K Timper, ...
Cell 165 (1), 125-138, 2016
862016
Hepatic Bax inhibitor-1 inhibits IRE1α and protects from obesity-associated insulin resistance and glucose intolerance
B Bailly-Maitre, BF Belgardt, SD Jordan, B Coornaert, MJ von Freyend, ...
Journal of Biological Chemistry 285 (9), 6198-6207, 2010
792010
Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits
S Hult, R Soylu, T Björklund, BF Belgardt, J Mauer, JC Brüning, D Kirik, ...
Cell metabolism 13 (4), 428-439, 2011
762011
Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
J Mauer, B Chaurasia, L Plum, T Quast, B Hampel, M Blüher, W Kolanus, ...
PLoS genetics 6 (5), e1000938, 2010
722010
Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humans
R Bilkovski, DM Schulte, F Oberhauser, J Mauer, B Hampel, C Gutschow, ...
International journal of obesity 35 (11), 1450, 2011
672011
Myeloid-cell-derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity
A Jais, M Solas, H Backes, B Chaurasia, A Kleinridders, S Theurich, ...
Cell 165 (4), 882-895, 2016
642016
Visfatin/PBEF/Nampt and resistin expressions in circulating blood monocytes are differentially related to obesity and type 2 diabetes in humans
M Laudes, F Oberhauser, DM Schulte, S Freude, R Bilkovski, J Mauer, ...
Hormone and Metabolic Research 42 (04), 268-273, 2010
622010
IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity
J Braune, U Weyer, C Hobusch, J Mauer, JC Brüning, I Bechmann, ...
The Journal of Immunology 198 (7), 2927-2934, 2017
582017
Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-κB activation in macrophages
B Chaurasia, J Mauer, L Koch, J Goldau, AS Kock, JC Brüning
Molecular and cellular biology 30 (17), 4354-4366, 2010
542010
Dicer1–miR-328–Bace1 signalling controls brown adipose tissue differentiation and function
M Oliverio, E Schmidt, J Mauer, C Baitzel, N Hansmeier, S Khani, ...
Nature cell biology 18 (3), 328, 2016
442016
An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning
M Sevgi, L Rigoux, AB Kühn, J Mauer, L Schilbach, ME Hess, ...
Journal of Neuroscience 35 (36), 12584-12592, 2015
422015
Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity
A Kukat, SA Dogan, D Edgar, A Mourier, C Jacoby, P Maiti, J Mauer, ...
PLoS genetics 10 (6), e1004385, 2014
372014
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