| Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals EK Sims, BN Bundy, K Stier, E Serti, N Lim, SA Long, SM Geyer, A Moran, ... Science translational medicine 13 (583), eabc8980, 2021 | 179 | 2021 |
| Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, ... Diabetologia 61, 1124-1134, 2018 | 135 | 2018 |
| 100 years of insulin: celebrating the past, present and future of diabetes therapy EK Sims, ALJ Carr, RA Oram, LA DiMeglio, C Evans-Molina Nature medicine 27 (7), 1154-1164, 2021 | 132 | 2021 |
| Beta cells in type 1 diabetes: mass and function; sleeping or dead? RA Oram, EK Sims, C Evans-Molina Diabetologia 62, 567-577, 2019 | 123 | 2019 |
| Elevations in the fasting serum proinsulin–to–C-peptide ratio precede the onset of type 1 diabetes EK Sims, Z Chaudhry, R Watkins, F Syed, J Blum, F Ouyang, SM Perkins, ... Diabetes care 39 (9), 1519-1526, 2016 | 123 | 2016 |
| MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells EK Sims, AJ Lakhter, E Anderson-Baucum, T Kono, X Tong, ... Diabetologia 60 (6), 1057-1065, 2017 | 91 | 2017 |
| Screening for type 1 diabetes in the general population: a status report and perspective EK Sims, REJ Besser, C Dayan, C Geno Rasmussen, C Greenbaum, ... Diabetes 71 (4), 610-623, 2022 | 89 | 2022 |
| Proinsulin secretion is a persistent feature of type 1 diabetes EK Sims, HT Bahnson, J Nyalwidhe, L Haataja, AK Davis, C Speake, ... Diabetes care 42 (2), 258-264, 2019 | 89 | 2019 |
| Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors TM Kono, EK Sims, DR Moss, W Yamamoto, G Ahn, J Diamond, X Tong, ... Stem cells 32 (7), 1831-1842, 2014 | 84 | 2014 |
| Streptozotocin is equally diabetogenic whether administered to fed or fasted mice ZZ Chaudhry, DL Morris, DR Moss, EK Sims, Y Chiong, T Kono, ... Laboratory animals 47 (4), 257-265, 2013 | 80 | 2013 |
| Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial SE Gitelman, BN Bundy, E Ferrannini, N Lim, JL Blanchfield, LA DiMeglio, ... The Lancet Diabetes & Endocrinology 9 (8), 502-514, 2021 | 73 | 2021 |
| β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis C Evans-Molina, EK Sims, LA DiMeglio, HM Ismail, AK Steck, JP Palmer, ... JCI insight 3 (15), 2018 | 69 | 2018 |
| Effect of verapamil on pancreatic beta cell function in newly diagnosed pediatric type 1 diabetes: a randomized clinical trial GP Forlenza, J McVean, RW Beck, C Bauza, R Bailey, B Buckingham, ... Jama 329 (12), 990-999, 2023 | 62 | 2023 |
| Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway M Hatanaka, B Maier, EK Sims, AT Templin, RN Kulkarni, C Evans-Molina, ... Diabetes 63 (10), 3404-3415, 2014 | 61 | 2014 |
| Minireview: emerging roles for extracellular vesicles in diabetes and related metabolic disorders AJ Lakhter, EK Sims Molecular endocrinology 29 (11), 1535-1548, 2015 | 59 | 2015 |
| Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains EK Sims, M Hatanaka, DL Morris, SA Tersey, T Kono, ZZ Chaudry, ... American Journal of Physiology-Endocrinology and Metabolism 305 (12), E1495 …, 2013 | 57 | 2013 |
| Biomarkers of β-cell stress and death in type 1 diabetes RG Mirmira, EK Sims, F Syed, C Evans-Molina Current diabetes reports 16, 1-9, 2016 | 50 | 2016 |
| The role of beta-cell dysfunction in early type 1 diabetes EK Sims, RG Mirmira, C Evans-Molina Current Opinion in Endocrinology, Diabetes and Obesity 27 (4), 215-224, 2020 | 42 | 2020 |
| Biomarkers of islet beta cell stress and death in type 1 diabetes EK Sims, C Evans-Molina, SA Tersey, DL Eizirik, RG Mirmira Diabetologia 61, 2259-2265, 2018 | 41 | 2018 |
| Abnormalities in proinsulin processing in islets from individuals with longstanding T1D EK Sims, F Syed, J Nyalwidhe, HT Bahnson, L Haataja, C Speake, ... Translational Research 213, 90-99, 2019 | 40 | 2019 |
Raghavendra MirmiraThe University of ChicagoBestätigte E-Mail-Adresse bei uchicago.edu
