| Synthesis and structure− activity relationship of a new series of COX-2 selective inhibitors: 1, 5-diarylimidazoles C Almansa, J Alfón, AF de Arriba, FL Cavalcanti, I Escamilla, LA Gómez, ... Journal of medicinal chemistry 46 (16), 3463-3475, 2003 | 178 | 2003 |
| Effects of statins in thrombosis and aortic lesion development in a dyslipemic rabbit model J Alfon, CP Palazon, T Royo, L Badimon Thrombosis and haemostasis 81 (05), 822-827, 1999 | 91 | 1999 |
| Nitric oxide synthase II (NOS II) gene expression correlates with atherosclerotic intimal thickening. Preventive effects of HMG-CoA reductase inhibitors J Alfon, JF Guasch, M Berrozpe, L Badimon Atherosclerosis 145 (2), 325-331, 1999 | 90 | 1999 |
| HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma … J Martı́nez-González, J Alfón, M Berrozpe, L Badimon Atherosclerosis 159 (1), 27-33, 2001 | 85 | 2001 |
| Platelet deposition on eroded vessel walls at a stenotic shear rate is inhibited by lipid-lowering treatment with atorvastatin J Alfon, T Royo, X Garcia-Moll, L Badimon Arteriosclerosis, thrombosis, and vascular biology 19 (7), 1812-1817, 1999 | 81 | 1999 |
| The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells P Muñoz-Guardiola, J Casas, E Megías-Roda, S Solé, H Perez-Montoyo, ... Autophagy, 1-18, 2020 | 80 | 2020 |
| The new antitumor drug ABTL0812 inhibits the Akt/mTORC1 axis by upregulating tribbles-3 pseudokinase T Erazo, M Lorente, A López-Plana, P Muñoz-Guardiola, ... Clinical Cancer Research 22 (10), 2508-2519, 2016 | 71 | 2016 |
| Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer I Felip, CP Moiola, C Megino-Luque, C Lopez-Gil, S Cabrera, ... Gynecologic oncology 153 (2), 425-435, 2019 | 37 | 2019 |
| A small molecule, orally active, α4β1/α4β7 dual antagonist reduces leukocyte infiltration and airway hyper‐responsiveness in an experimental model of allergic asthma in Brown … J Cortijo, MJ Sanz, A Iranzo, JL Montesinos, YNA Nabah, J Alfón, ... British journal of pharmacology 147 (6), 661-670, 2006 | 37 | 2006 |
| Effect of gemfibrozil on peripheral atherosclerosis and platelet activation in a pig model of hyperlipidemia T Royo, J Alfon, M Berrozpe, L Badimon European journal of clinical investigation 30 (10), 843-852, 2000 | 29 | 2000 |
| Effects of reducing LDL and increasing HDL with gemfibrozil in experimental coronary lesion development and thrombotic risk CP Palazón, J Alfon, P Gaffney, M Berrozpe, T Royo, L Badimon Atherosclerosis 136 (2), 333-345, 1998 | 29 | 1998 |
| Cell biology of restenosis post-angioplasty. L Badimon, J Alfon, T Royo, M Berrozpe, J Martinez-Gonzalez, F Vidal, ... Zeitschrift fur Kardiologie 84, 145-149, 1995 | 25 | 1995 |
| The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer A López‐Plana, P Fernández‐Nogueira, P Muñoz‐Guardiola, ... International Journal of Cancer, 2020 | 17 | 2020 |
| A first-in-human phase I/Ib dose-escalation clinical trial of the autophagy inducer ABTL0812 in patients with advanced solid tumours L Vidal, I Victoria, L Gaba, MG Martín, M Brunet, H Colom, M Cortal, ... European Journal of Cancer 146, 87-94, 2021 | 14 | 2021 |
| UR-60427, a novel H4 receptor-inverse agonist that shows good efficacy in a rat asthma model J Alfon, N Ardanaz, B Gil-Torregrosa, A Fernández, D Balsa, E Carceller, ... Inflammation research 59 (2), 199-200, 2010 | 11 | 2010 |
| The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis L París-Coderch, A Soriano, C Jiménez, T Erazo, P Muñoz-Guardiola, ... Cell Death & Disease 11 (9), 1-10, 2020 | 10 | 2020 |
| Alternative binding assay of gp iib/iiia antagonists with a nonradioactive labeling method of platelets J Alfón, AF de Arriba, LA Gómez-Casajús, M Merlos Thrombosis research 102 (3), 247-253, 2001 | 10 | 2001 |
| Efficacy Of UR-63325, A New Histamine H4 Receptor Antagonist, In House Dust Mite-Induced Mouse Asthma Models J Alfon, S Sanchez-Gomez, C Salcedo, A Fernandez, B Gil-Torregrosa, ... A31. OPTIMIZING THERAPEUTIC STRATEGIES IN AIRWAYS DISEASE, A1302-A1302, 2011 | 7 | 2011 |
| Efficacy of Ur-63325, a new histamine H4 receptor antagonist, in house dust mite-induced mouse asthma models J Alfon, S Sanchez-Gomez, C Salcedo, A Fernandez, B Gil-Torregrosa, ... A31. OPTIMIZING THERAPEUTIC STRATEGIES IN AIRWAYS DISEASE, A1302-A1302, 2011 | 7 | 2011 |
| A small molecule, orally active,# 9454# 9461/# 9454# 9467 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic … J Cortijo, MJ Sanz, A Iranzo, JL Montesinos, YNA Nabah, J Alfón, ... British Journal of Pharmacology 147 (6), 661-670, 2006 | 6 | 2006 |
