| Evolution of genes and genomes on the Drosophila phylogeny AG Clark, L Pachter Nature 450 (7167), 203-218, 2007 | 2052 | 2007 |
| Ten years of pathway analysis: current approaches and outstanding challenges P Khatri, M Sirota, AJ Butte PLoS computational biology 8 (2), e1002375, 2012 | 1507 | 2012 |
| Identifying a high fraction of the human genome to be under selective constraint using GERP++ EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou PLoS computational biology 6 (12), e1001025, 2010 | 1477 | 2010 |
| Discovery and preclinical validation of drug indications using compendia of public gene expression data M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ... Science translational medicine 3 (96), 96ra77-96ra77, 2011 | 739 | 2011 |
| Systematic pan-cancer analysis of tumour purity D Aran, M Sirota, AJ Butte Nature communications 6 (1), 1-12, 2015 | 727 | 2015 |
| Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease JT Dudley, M Sirota, M Shenoy, RK Pai, S Roedder, AP Chiang, ... Science translational medicine 3 (96), 96ra76-96ra76, 2011 | 544 | 2011 |
| Comprehensive analysis of normal adjacent to tumor transcriptomes D Aran, R Camarda, J Odegaard, H Paik, B Oskotsky, G Krings, A Goga, ... Nature communications 8 (1), 1-14, 2017 | 307 | 2017 |
| B cell exchange across the blood-brain barrier in multiple sclerosis H von Büdingen, TC Kuo, M Sirota, CJ van Belle, L Apeltsin, J Glanville, ... The Journal of Clinical Investigation, 2012 | 217 | 2012 |
| Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis A Palanichamy, L Apeltsin, TC Kuo, M Sirota, S Wang, SJ Pitts, ... Science translational medicine 6 (248), 248ra106-248ra106, 2014 | 212 | 2014 |
| Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association R Chen, EV Davydov, M Sirota, AJ Butte PloS one 5 (10), e13574, 2010 | 177 | 2010 |
| Autoimmune disease classification by inverse association with SNP alleles M Sirota, MA Schaub, S Batzoglou, WH Robinson, AJ Butte PLoS genetics 5 (12), e1000792, 2009 | 175 | 2009 |
| Cross-tissue analysis of gene and protein expression in normal and cancer tissues I Kosti, N Jain, D Aran, AJ Butte, M Sirota Scientific reports 6 (1), 1-16, 2016 | 146 | 2016 |
| Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes K Kodama, M Horikoshi, K Toda, S Yamada, K Hara, J Irie, M Sirota, ... Proceedings of the National Academy of Sciences 109 (18), 7049-7054, 2012 | 137 | 2012 |
| CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novogene prediction SS Gross, CB Do, M Sirota, S Batzoglou Genome biology 8 (12), 1-16, 2007 | 123 | 2007 |
| Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte Nature communications 8 (1), 1-12, 2017 | 122 | 2017 |
| Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy MS Ghaemi, DB DiGiulio, K Contrepois, B Callahan, TTM Ngo, ... Bioinformatics 35 (1), 95-103, 2019 | 94 | 2019 |
| Environmental influences on reproductive health: the importance of chemical exposures A Wang, A Padula, M Sirota, TJ Woodruff Fertility and sterility 106 (4), 905-929, 2016 | 91 | 2016 |
| Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types K Yu, B Chen, D Aran, J Charalel, C Yau, DM Wolf, LJ Van‘T Veer, ... Nature communications 10 (1), 1-11, 2019 | 78 | 2019 |
| Sex differences in disease risk from reported genome-wide association study findings LY Liu, MA Schaub, M Sirota, AJ Butte Human genetics 131 (3), 353-364, 2012 | 74 | 2012 |
| Drug discovery in a multidimensional world: systems, patterns, and networks JT Dudley, E Schadt, M Sirota, AJ Butte, E Ashley Journal of cardiovascular translational research 3 (5), 438-447, 2010 | 70 | 2010 |
Atul J. ButteDirector, Bakar Computational Health Sciences Institute, University of California, San FranciscoVerified email at ucsf.edu
