Martin Hofmann-Apitius

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Erfan YounesiSenior Scientist, Information Technology for Translational MedicineVerified email at schegerd.de
Christoph M. FriedrichProfessor for Biomedical Computer Science, University of Applied Sciences and Arts, DortmundVerified email at computer.org
Roman KlingerSenior lecturer, Institut für Maschinelle Sprachverarbeitung, Uni StuttgartVerified email at ims.uni-stuttgart.de
Dr. Harsha GurulingappaMerck KGaAVerified email at merckgroup.com
ashutosh malhotraResearch associateVerified email at scai.fraunhofer.de
Holger FröhlichHead of AI & Data Science Group & Deputy Head of Department of Bioinformatics at Fraunhofer SCAIVerified email at bit.uni-bonn.de
Michaela GündelBonn-Aachen International Center for Information Technology B-IT, University of BonnVerified email at scai-extern.fraunhofer.de
Laura I. FurlongGRIB, Hospital del Mar Medical Research Institute (IMIM), DCEXS (UPF)Verified email at upf.edu
Siegfried BenknerProfessor of Computer Science, University of Vienna, AustriaVerified email at univie.ac.at
Ferran SanzDirector, Research Programme on Biomedical Informatics (GRIB), IMIM, Universitat Pompeu Fabra, BarcelonaVerified email at imim.es
Mohammad ShahidFraunhofer Institute SCAI, b-it, University of BonnVerified email at koeln.de
Philippe ThomasGerman Research Center for Artificial IntelligenceVerified email at dfki.de
Philippe BijlengaMédecin adjoint aggrégé, Hôpitaux Universitaire de GenèveVerified email at hcuge.ch
Henning MüllerProfessor in computer science at HES-SO & in radiology at the University of GenevaVerified email at hevs.ch
Baldo OlivaUniversitat Pompeu fabraVerified email at upf.edu
Martin BoekerInst. of Med. Biometry & Statistics, Medical Data Science, University of Freiburg, GermanyVerified email at uniklinik-freiburg.de
MCJM SturkenboomUniversity Medical Center UtrechtVerified email at umcutrecht.nl
Dr. Marc JacobsFraunhofer SCAI.BioVerified email at scai.fraunhofer.de
Daniel RüfenachtNeuroradiologyVerified email at hirslanden.ch

Martin Hofmann-Apitius

Professor für Angewandte Life Science Informatik, Universität Bonn

Verified email at scai.fraunhofer.de

Modellierung neurodegenerativer Erkrankungen


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A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells U Günthert, M Hofmann, W Rudy, S Reber, M Zöller, I Hauβmann, ... Cell 65 (1), 13-24, 1991	2127	1991
Participation in normal immune responses of a metastasis-inducing splice variant of CD44 R Arch, K Wirth, M Hofmann, H Ponta, S Matzku, P Herrlich, M Zoller Science 257 (5070), 682-685, 1992	529	1992
CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines M Hofmann, W Rudy, M Zöller, C Tölg, H Ponta, P Herrlich, U Günthert Cancer Research 51 (19), 5292-5297, 1991	443	1991
A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps. KH Heider, M Hofmann, E Hors, F van den Berg, H Ponta, P Herrlich, ... The Journal of cell biology 120 (1), 227-233, 1993	430	1993
Splicing choice from ten variant exons establishes CD44 variability C Tölg, M Hofmann, P Herrlich, H Ponta Nucleic acids research 21 (5), 1225-1229, 1993	333	1993
A high throughput screening for rarely transcribed differentially expressed genes OD von Stein, WG Thies, M Hofmann Nucleic Acids Research 25 (13), 2598-2602, 1997	323	1997
The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior W Rudy, M Hofmann, R Schwartz-Albiez, M Zöller, KH Heider, H Ponta, ... Cancer research 53 (6), 1262-1268, 1993	312	1993
An essential role for CD44 variant isoforms in epidermal Langerhans cell and blood dendritic cell function JM Weiss, J Sleeman, AC Renkl, H Dittmar, CC Termeer, S Taxis, ... The Journal of cell biology 137 (5), 1137-1147, 1997	210	1997
Hyaluronan-oligosaccharide-induced transcription of metalloproteases C Fieber, P Baumann, R Vallon, C Termeer, JC Simon, M Hofmann, ... Journal of cell science 117 (2), 359-367, 2004	201	2004
CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferation V Assmann, C Fieber, P Herrlich, M Hofmann, CC Termeer, T Ahrens, ... Journal of Investigative Dermatology 116 (1), 93-101, 2001	196	2001
Development of a benchmark corpus to support the automatic extraction of drug-related adverse effects from medical case reports H Gurulingappa, AM Rajput, A Roberts, J Fluck, M Hofmann-Apitius, ... Journal of biomedical informatics 45 (5), 885-892, 2012	191	2012
Gene expression patterns associated with the metastatic phenotype in rodent and human tumors A Nestl, OD Von Stein, K Zatloukal, WG Thies, P Herrlich, M Hofmann, ... Cancer research 61 (4), 1569-1577, 2001	181	2001
A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF … M Hofmann, W Rudy, U Günthert, SG Zimmer, V Zawadzki, M Zöller, ... Cancer research 53 (7), 1516-1521, 1993	179	1993
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid T Ahrens, JP Sleeman, CM Schempp, N Howells, M Hofmann, H Ponta, ... Oncogene 20 (26), 3399-3408, 2001	157	2001
The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells V Assmann, JF Marshall, C Fieber, M Hofmann, IR Hart Journal of cell science 111 (12), 1685-1694, 1998	156	1998
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity. J Sleeman, W Rudy, M Hofmann, J Moll, P Herrlich, H Ponta The Journal of cell biology 135 (4), 1139-1150, 1996	147	1996
Detection of IUPAC and IUPAC-like chemical names R Klinger, C Kolářik, J Fluck, M Hofmann-Apitius, CM Friedrich Bioinformatics 24 (13), i268-i276, 2008	140	2008
Prevalence and risk factors for Plasmodium falciparum malaria in pregnant women of eastern Sudan I Adam, AH Khamis, MI Elbashir Malaria journal 4 (1), 1-4, 2005	128	2005
Grid-enabled virtual screening against malaria N Jacq, J Salzemann, F Jacq, Y Legre, E Medernach, J Montagnat, ... Journal of Grid Computing 6 (1), 29-43, 2008	106	2008
Variant CD44 adhesion molecules are expressed in human brain metastases but not in glioblastomas H Li, MF Hamou, N de Tribolet, R Jaufeerally, M Hofmann, AC Diserens, ... Cancer research 53 (22), 5345-5349, 1993	105	1993

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