TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ... Nature 554 (7693), 544-548, 2018 | 3731 | 2018 |
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma T Powles, ZJ Assaf, N Davarpanah, R Banchereau, BE Szabados, ... Nature 595 (7867), 432-437, 2021 | 352 | 2021 |
High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade KC Yuen, LF Liu, V Gupta, S Madireddi, S Keerthivasan, C Li, ... Nature medicine 26 (5), 693-698, 2020 | 280 | 2020 |
Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial T Powles, KC Yuen, S Gillessen, EE Kadel Iii, D Rathkopf, N Matsubara, ... Nature medicine 28 (1), 144-153, 2022 | 113 | 2022 |
Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters KC Yuen, BD Slaughter, JL Gerton Science advances 3 (6), e1700191, 2017 | 72 | 2017 |
The immunoglobulin superfamily receptome defines cancer-relevant networks associated with clinical outcome E Verschueren, B Husain, K Yuen, Y Sun, S Paduchuri, Y Senbabaoglu, ... Cell 182 (2), 329-344. e19, 2020 | 68 | 2020 |
Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase CY Yuen, WT Wong, XY Tian, SL Wong, CW Lau, J Yu, B Tomlinson, ... Cardiovascular research 90 (1), 122-129, 2011 | 67 | 2011 |
IMbassador250: a phase III trial comparing atezolizumab with enzalutamide vs enzalutamide alone in patients with metastatic castration-resistant prostate cancer (mCRPC) CJ Sweeney, S Gillessen, D Rathkopf, N Matsubara, C Drake, K Fizazi, ... Cancer Res 80 (16 Suppl), 2020 | 61 | 2020 |
Taking cohesin and condensin in context KC Yuen, JL Gerton PLoS genetics 14 (1), e1007118, 2018 | 58 | 2018 |
Safety and clinical activity of atezolizumab in patients with metastatic castration-resistant prostate cancer: a phase I study DP Petrylak, Y Loriot, DR Shaffer, F Braiteh, J Powderly, LC Harshman, ... Clinical Cancer Research 27 (12), 3360-3369, 2021 | 57 | 2021 |
Etiology and pathogenesis of the cohesinopathies M Zakari, K Yuen, JL Gerton Wiley Interdisciplinary Reviews: Developmental Biology 4 (5), 489-504, 2015 | 49 | 2015 |
CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy MA Huseni, L Wang, JE Klementowicz, K Yuen, B Breart, C Orr, L Liu, Y Li, ... Cell Reports Medicine 4 (1), 2023 | 39 | 2023 |
NIPBL controls RNA biogenesis to prevent activation of the stress kinase PKR KC Yuen, B Xu, ID Krantz, JL Gerton Cell reports 14 (1), 93-102, 2016 | 37 | 2016 |
From skeleton to cytoskeleton: osteocalcin transforms vascular fibroblasts to myofibroblasts via angiotensin II and Toll-like receptor 4 CY Yuen, SL Wong, CW Lau, SY Tsang, A Xu, Z Zhu, CF Ng, X Yao, ... Circulation Research 111 (3), e55-e66, 2012 | 36 | 2012 |
Tumor, immune, and stromal characteristics associated with clinical outcomes with atezolizumab (atezo)+ platinum-based chemotherapy (PBC) or atezo monotherapy (mono) versus PBC … MD Galsky, R Banchereau, HR Hamidi, N Leng, W Harris, PH O'Donnell, ... Journal of Clinical Oncology 38 (15_suppl), 5011-5011, 2020 | 30 | 2020 |
Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells K Aoto, LL Sandell, NEB Tjaden, KC Yuen, KEN Watt, BL Black, M Durnin, ... Developmental biology 402 (1), 3-16, 2015 | 29 | 2015 |
A phase Ib study of atezolizumab with radium-223 dichloride in men with metastatic castration-resistant prostate cancer L Fong, MJ Morris, O Sartor, CS Higano, L Pagliaro, A Alva, LJ Appleman, ... Clinical Cancer Research 27 (17), 4746-4756, 2021 | 26 | 2021 |
Tumor fusion burden as a hallmark of immune infiltration in prostate cancer MC Wagle, J Castillo, S Srinivasan, T Holcomb, KC Yuen, EE Kadel, ... Cancer immunology research 8 (7), 844-850, 2020 | 13 | 2020 |
Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD … M Fehlings, L Kim, X Guan, K Yuen, A Tafazzol, S Sanjabi, OA Zill, ... Journal for Immunotherapy of Cancer 10 (8), 2022 | 12 | 2022 |
Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters. Sci Adv 3: e1700191 KC Yuen, BD Slaughter, JL Gerton | 12 | 2017 |