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Kobe C. Yuen
Kobe C. Yuen
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TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ...
Nature 554 (7693), 544-548, 2018
37312018
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma
T Powles, ZJ Assaf, N Davarpanah, R Banchereau, BE Szabados, ...
Nature 595 (7867), 432-437, 2021
3522021
High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade
KC Yuen, LF Liu, V Gupta, S Madireddi, S Keerthivasan, C Li, ...
Nature medicine 26 (5), 693-698, 2020
2802020
Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial
T Powles, KC Yuen, S Gillessen, EE Kadel Iii, D Rathkopf, N Matsubara, ...
Nature medicine 28 (1), 144-153, 2022
1132022
Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters
KC Yuen, BD Slaughter, JL Gerton
Science advances 3 (6), e1700191, 2017
722017
The immunoglobulin superfamily receptome defines cancer-relevant networks associated with clinical outcome
E Verschueren, B Husain, K Yuen, Y Sun, S Paduchuri, Y Senbabaoglu, ...
Cell 182 (2), 329-344. e19, 2020
682020
Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase
CY Yuen, WT Wong, XY Tian, SL Wong, CW Lau, J Yu, B Tomlinson, ...
Cardiovascular research 90 (1), 122-129, 2011
672011
IMbassador250: a phase III trial comparing atezolizumab with enzalutamide vs enzalutamide alone in patients with metastatic castration-resistant prostate cancer (mCRPC)
CJ Sweeney, S Gillessen, D Rathkopf, N Matsubara, C Drake, K Fizazi, ...
Cancer Res 80 (16 Suppl), 2020
612020
Taking cohesin and condensin in context
KC Yuen, JL Gerton
PLoS genetics 14 (1), e1007118, 2018
582018
Safety and clinical activity of atezolizumab in patients with metastatic castration-resistant prostate cancer: a phase I study
DP Petrylak, Y Loriot, DR Shaffer, F Braiteh, J Powderly, LC Harshman, ...
Clinical Cancer Research 27 (12), 3360-3369, 2021
572021
Etiology and pathogenesis of the cohesinopathies
M Zakari, K Yuen, JL Gerton
Wiley Interdisciplinary Reviews: Developmental Biology 4 (5), 489-504, 2015
492015
CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy
MA Huseni, L Wang, JE Klementowicz, K Yuen, B Breart, C Orr, L Liu, Y Li, ...
Cell Reports Medicine 4 (1), 2023
392023
NIPBL controls RNA biogenesis to prevent activation of the stress kinase PKR
KC Yuen, B Xu, ID Krantz, JL Gerton
Cell reports 14 (1), 93-102, 2016
372016
From skeleton to cytoskeleton: osteocalcin transforms vascular fibroblasts to myofibroblasts via angiotensin II and Toll-like receptor 4
CY Yuen, SL Wong, CW Lau, SY Tsang, A Xu, Z Zhu, CF Ng, X Yao, ...
Circulation Research 111 (3), e55-e66, 2012
362012
Tumor, immune, and stromal characteristics associated with clinical outcomes with atezolizumab (atezo)+ platinum-based chemotherapy (PBC) or atezo monotherapy (mono) versus PBC …
MD Galsky, R Banchereau, HR Hamidi, N Leng, W Harris, PH O'Donnell, ...
Journal of Clinical Oncology 38 (15_suppl), 5011-5011, 2020
302020
Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells
K Aoto, LL Sandell, NEB Tjaden, KC Yuen, KEN Watt, BL Black, M Durnin, ...
Developmental biology 402 (1), 3-16, 2015
292015
A phase Ib study of atezolizumab with radium-223 dichloride in men with metastatic castration-resistant prostate cancer
L Fong, MJ Morris, O Sartor, CS Higano, L Pagliaro, A Alva, LJ Appleman, ...
Clinical Cancer Research 27 (17), 4746-4756, 2021
262021
Tumor fusion burden as a hallmark of immune infiltration in prostate cancer
MC Wagle, J Castillo, S Srinivasan, T Holcomb, KC Yuen, EE Kadel, ...
Cancer immunology research 8 (7), 844-850, 2020
132020
Single-cell analysis reveals clonally expanded tumor-associated CD57+ CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD …
M Fehlings, L Kim, X Guan, K Yuen, A Tafazzol, S Sanjabi, OA Zill, ...
Journal for Immunotherapy of Cancer 10 (8), 2022
122022
Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters. Sci Adv 3: e1700191
KC Yuen, BD Slaughter, JL Gerton
122017
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