Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue SV Molinski, S Ahmadi, W Ip, H Ouyang, A Villella, JP Miller, PS Lee, ... EMBO molecular medicine 9 (9), 1224-1243, 2017 | 106 | 2017 |
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ... NPJ genomic medicine 2 (1), 12, 2017 | 69 | 2017 |
Synergy of cAMP and calcium signaling pathways in CFTR regulation Z Bozoky, S Ahmadi, T Milman, TH Kim, K Du, M Di Paola, S Pasyk, ... Proceedings of the national academy of sciences 114 (11), E2086-E2095, 2017 | 64 | 2017 |
SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells M Di Paola, AJ Park, S Ahmadi, EJ Roach, YS Wu, M Struder-Kypke, ... MBio 8 (6), 10.1128/mbio. 02073-17, 2017 | 48 | 2017 |
SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion S Ahmadi, S Xia, YS Wu, M Di Paola, R Kissoon, C Luk, F Lin, K Du, ... Elife 7, e37963, 2018 | 36 | 2018 |
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients JX Jiang, L Wellhauser, O Laselva, I Utkina, Z Bozoky, T Gunawardena, ... Stem cell reports 16 (11), 2825-2837, 2021 | 24 | 2021 |
Augmentation of cystic fibrosis transmembrane conductance regulator function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake. Implications for … S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola, K Du, S Xia, ... American journal of respiratory cell and molecular biology 61 (6), 755-764, 2019 | 14 | 2019 |
Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium SH Lee, S Hadipour-Lakmehsari, DH Kim, M Di Paola, U Kuzmanov, ... Scientific Data 7 (1), 425, 2020 | 12 | 2020 |
Conversion of human and mouse fibroblasts into lung-like epithelial cells AP Wong, S Shojaie, Q Liang, S Xia, M Di Paola, S Ahmadi, C Bilodeau, ... Scientific reports 9 (1), 9027, 2019 | 12 | 2019 |
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts ACT Teng, L Gu, M Di Paola, R Lakin, ZJ Williams, A Au, W Chen, ... Nature Communications 13 (1), 6166, 2022 | 9 | 2022 |
High-throughput functional analysis of CFTR and other apically localized proteins in iPSC-derived human intestinal organoids S Xia, Z Bozóky, M Di Paola, O Laselva, S Ahmadi, JX Jiang, AL Pitstick, ... Cells 10 (12), 3419, 2021 | 8 | 2021 |
High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids S Xia, Z Bozóky, O Laselva, M Di Paola, S Ahmadi, JX Jiang, A Pitstick, ... bioRxiv, 2021.07. 07.451180, 2021 | 5 | 2021 |
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia. npj Genomic Medicine. 2 S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ... DOI: https://doi. org/10.1038/s41525-017-0015-6, PMID 28649446, 2017 | 4 | 2017 |
Augmentation of CFTR function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake: implications for treatment of cystic fibrosis S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola Am J Respir Cell Mol Biol 10, 2019 | 3 | 2019 |
Noninvasive Quantification of Contractile Dynamics in Cardiac Cells, Spheroids, and Organs-on-a-Chip Using High-Frequency Ultrasound EM Strohm, NI Callaghan, Y Ding, N Latifi, N Rafatian, S Funakoshi, ... ACS nano 18 (1), 314-327, 2023 | 2 | 2023 |
SLC6A14 Modifies Fluid Secretory Capacity of Cystic Fibrosis Affected Epithelium by Enhancing CFTR Channel Function S Ahmadi, C Luk, S Xia, M Di Paola, T Chung, J Rommens, C Bear Biophysical Journal 108 (2), 19a-20a, 2015 | 2 | 2015 |
SLC6A14 Enhances CFTR Channel Activity in the Cystic Fibrosis Affected Lung Epithelium S Ahmadi, S Xia, M Di Paola, W Ip, J Rommens, T Gonska, CE Bear Biophysical Journal 110 (3), 452a, 2016 | 1 | 2016 |
Abstract P1027: Confocal And Mass Spectrometry-based Investigation Of REEP5 Depletion By AAV9 In The Mouse Heart M Di Paola, C Reitz, U Kuzmanov, K Jia, A Teng, A Gramolini Circulation Research 133 (Suppl_1), AP1027-AP1027, 2023 | | 2023 |
A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines S Xia, M Di Paola, NL Jones, CE Bear JoVE (Journal of Visualized Experiments), e63528, 2022 | | 2022 |
Reduced Cardiac Tmem65 In Mouse Hearts Results In Intercalated Disc Defects And Eventual Dilated Cardiomyopathy With Cardiac Fibrosis AC Teng, L Gu, M Di Paola, Z Williams, A Au, N Callaghan, FH Zadeh, ... CIRCULATION RESEARCH 129, 2021 | | 2021 |