| The response of bone marrow-derived mesenchymal stem cells to dynamic compression following TGF-β3 induced chondrogenic differentiation SD Thorpe, CT Buckley, T Vinardell, FJ O’Brien, VA Campbell, DJ Kelly Annals of biomedical engineering 38 (9), 2896-2909, 2010 | 246 | 2010 |
| Biophysical regulation of chromatin architecture instills a mechanical memory in mesenchymal stem cells SJ Heo, SD Thorpe, TP Driscoll, RL Duncan, DA Lee, RL Mauck Scientific reports 5 (1), 16895, 2015 | 194 | 2015 |
| Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity SJ Heo, TP Driscoll, SD Thorpe, NL Nerurkar, BM Baker, MT Yang, ... Elife 5, e18207, 2016 | 172 | 2016 |
| The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels CT Buckley, SD Thorpe, FJ O’Brien, AJ Robinson, DJ Kelly Journal of the mechanical behavior of biomedical materials 2 (5), 512-521, 2009 | 166 | 2009 |
| Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells SD Thorpe, CT Buckley, T Vinardell, FJ O’Brien, VA Campbell, DJ Kelly Biochemical and biophysical research communications 377 (2), 458-462, 2008 | 146 | 2008 |
| Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells G Pattappa, SD Thorpe, NC Jegard, HK Heywood, JD de Bruijn, DA Lee Tissue Engineering Part C: Methods 19 (1), 68-79, 2013 | 138 | 2013 |
| Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells CT Buckley, T Vinardell, SD Thorpe, MG Haugh, E Jones, D McGonagle, ... Journal of biomechanics 43 (5), 920-926, 2010 | 133 | 2010 |
| Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression EG Meyer, CT Buckley, SD Thorpe, DJ Kelly Journal of biomechanics 43 (13), 2516-2523, 2010 | 120 | 2010 |
| Cell–matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure AJ Steward, SD Thorpe, T Vinardell, CT Buckley, DR Wagner, DJ Kelly Acta Biomaterialia 8 (6), 2153-2159, 2012 | 105 | 2012 |
| Mechanical stimulation: a crucial element of organ-on-chip models CL Thompson, S Fu, HK Heywood, MM Knight, SD Thorpe Frontiers in bioengineering and biotechnology 8, 602646, 2020 | 96 | 2020 |
| Chondrogenesis and Integration of Mesenchymal Stem Cells Within an In Vitro Cartilage Defect Repair Model T Vinardell, SD Thorpe, CT Buckley, DJ Kelly Annals of biomedical engineering 37, 2556-2565, 2009 | 95 | 2009 |
| Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway A Chronopoulos, SD Thorpe, E Cortes, D Lachowski, AJ Rice, ... Nature materials 19 (6), 669-678, 2020 | 86 | 2020 |
| Modulating gradients in regulatory signals within mesenchymal stem cell seeded hydrogels: a novel strategy to engineer zonal articular cartilage SD Thorpe, T Nagel, SF Carroll, DJ Kelly PLoS One 8 (4), e60764, 2013 | 84 | 2013 |
| Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival E Cortes, D Lachowski, B Robinson, M Sarper, JS Teppo, SD Thorpe, ... EMBO reports 20 (1), e46557, 2019 | 78 | 2019 |
| Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression MG Haugh, EG Meyer, SD Thorpe, T Vinardell, GP Duffy, DJ Kelly Tissue Engineering Part A 17 (23-24), 3085-3093, 2011 | 76 | 2011 |
| Adipogenic differentiation of hMSCs is mediated by recruitment of IGF‐1r onto the primary cilium associated with cilia elongation MT Dalbay, SD Thorpe, JT Connelly, JP Chapple, MM Knight Stem Cells 33 (6), 1952-1961, 2015 | 72 | 2015 |
| GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment E Cortes, M Sarper, B Robinson, D Lachowski, A Chronopoulos, ... EMBO reports 20 (1), e46556, 2019 | 68 | 2019 |
| Retinoic acid receptor‐β is downregulated in hepatocellular carcinoma and cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells E Cortes, D Lachowski, A Rice, A Chronopoulos, B Robinson, S Thorpe, ... Hepatology 69 (2), 785-802, 2019 | 60* | 2019 |
| European Society of Biomechanics SM Perren Award 2012: the external mechanical environment can override the influence of local substrate in determining stem cell fate SD Thorpe, CT Buckley, AJ Steward, DJ Kelly Journal of Biomechanics 45 (15), 2483-2492, 2012 | 60 | 2012 |
| Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity SD Thorpe, DA Lee Nucleus 8 (3), 287-300, 2017 | 59 | 2017 |
Daniel KellyTrinity Centre for Biomedical Engineering, School of Engineering, Trinity College DublinVerified email at tcd.ie
