Mapping cis- and trans-regulatory effects across multiple tissues in twins E Grundberg, KS Small, ÅK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ... Nature genetics 44 (10), 1084-1089, 2012 | 880 | 2012 |
DNA methylation and body-mass index: a genome-wide analysis KJ Dick, CP Nelson, L Tsaprouni, JK Sandling, D Aïssi, S Wahl, E Meduri, ... The Lancet 383 (9933), 1990-1998, 2014 | 856 | 2014 |
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements E Grundberg, E Meduri, JK Sandling, ÅK Hedman, S Keildson, A Buil, ... The American Journal of Human Genetics 93 (5), 876-890, 2013 | 380 | 2013 |
Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation LG Tsaprouni, TP Yang, J Bell, KJ Dick, S Kanoni, J Nisbet, A Viñuela, ... Epigenetics 9 (10), 1382-1396, 2014 | 364 | 2014 |
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia MA Dawson, EJ Gudgin, SJ Horton, G Giotopoulos, E Meduri, S Robson, ... Leukemia 28 (2), 311-320, 2014 | 175 | 2014 |
Differential methylation of the TRPA1 promoter in pain sensitivity JT Bell, AK Loomis, LM Butcher, F Gao, B Zhang, CL Hyde, J Sun, H Wu, ... Nature communications 5 (1), 2978, 2014 | 160 | 2014 |
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs M Gozdecka, E Meduri, M Mazan, K Tzelepis, M Dudek, AJ Knights, ... Nature genetics 50 (6), 883-894, 2018 | 136 | 2018 |
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML F Basheer, G Giotopoulos, E Meduri, H Yun, M Mazan, D Sasca, ... Journal of Experimental Medicine 216 (4), 966-981, 2019 | 102 | 2019 |
The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue AW Drong, G Nicholson, ÅK Hedman, E Meduri, E Grundberg, KS Small, ... PloS one 8 (2), e55923, 2013 | 98 | 2013 |
DNA double-strand break repair and the evolution of intron density A Farlow, E Meduri, C Schlötterer Trends in genetics 27 (1), 1-6, 2011 | 68 | 2011 |
Nonsense-Mediated Decay Enables Intron Gain in Drosophila A Farlow, E Meduri, M Dolezal, L Hua, C Schlötterer PLoS genetics 6 (1), e1000819, 2010 | 60 | 2010 |
InSatDb: a microsatellite database of fully sequenced insect genomes S Archak, E Meduri, PS Kumar, J Nagaraju Nucleic Acids Research 35 (suppl_1), D36-D39, 2007 | 56 | 2007 |
A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression G Giotopoulos, L van der Weyden, H Osaki, AG Rust, P Gallipoli, E Meduri, ... Journal of Experimental Medicine 212 (10), 1551-1569, 2015 | 45 | 2015 |
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia B Pardieu, J Pasanisi, F Ling, R Dal Bello, J Penneroux, A Su, ... Leukemia 36 (6), 1585-1595, 2022 | 30 | 2022 |
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression H Yun, N Narayan, S Vohra, G Giotopoulos, A Mupo, P Madrigal, D Sasca, ... Nature genetics 53 (10), 1443-1455, 2021 | 21 | 2021 |
Multiple Tissue Human Expression Resource Consortium Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in … E Grundberg, E Meduri, JK Sandling, AK Hedman, S Keildson, A Buil, ... Am J Hum Genet 93 (5), 876-890, 2013 | 14 | 2013 |
Multiple Tissue Human Expression Resource C E Grundberg, KS Small, AK Hedman, AC Nica, A Buil, S Keildson, JT Bell, ... Mapping cis-and trans-regulatory effects across multiple tissues in twins …, 2012 | 3 | 2012 |
The RNA editing landscape in acute myeloid leukemia reveals associations with disease mutations and clinical outcome E Meduri, C Breeze, L Marando, SE Richardson, BJP Huntly Iscience 25 (12), 2022 | 2 | 2022 |
Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction H Yun, S Vohra, A Mupo, G Giotopoulos, D Sasca, SJ Horton, ... Blood 134, 278, 2019 | 2 | 2019 |
Functional and molecular consequences of the Dnmt3aR882H mutation in acute myeloid leukaemia M Gozdecka, MM Mazan, V Iyer, A Farne, E Meduri, R Bautista, N Walker, ... Blood 126 (23), 2424, 2015 | 2 | 2015 |