| Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology NI Nissen, M Karsdal, N Willumsen Journal of Experimental & Clinical Cancer Research 38 (1), 115, 2019 | 401 | 2019 |
| Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls N Willumsen, CL Bager, DJ Leeming, V Smith, MA Karsdal, D Dornan, ... BMC cancer 13, 1-6, 2013 | 71 | 2013 |
| Collagen degradation products measured in serum can separate ovarian and breast cancer patients from healthy controls: A preliminary study CL Bager, N Willumsen, DJ Leeming, V Smith, MA Karsdal, D Dornan, ... Cancer Biomarkers 15 (6), 783-788, 2015 | 70 | 2015 |
| Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer N Willumsen, CL Bager, DJ Leeming, V Smith, C Christiansen, ... Cancer medicine 3 (5), 1136-1145, 2014 | 70 | 2014 |
| Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age-and sex-dependent remodeling of the extracellular matrix SN Kehlet, N Willumsen, G Armbrecht, R Dietzel, S Brix, K Henriksen, ... PloS one 13 (3), e0194458, 2018 | 67 | 2018 |
| Serological assessment of activated fibroblasts by alpha-smooth muscle actin (α-SMA): a noninvasive biomarker of activated fibroblasts in lung disorders SH Nielsen, N Willumsen, DJ Leeming, SJ Daniels, S Brix, MA Karsdal, ... Translational oncology 12 (2), 368-374, 2019 | 65 | 2019 |
| Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients C Jensen, DH Madsen, M Hansen, H Schmidt, IM Svane, MA Karsdal, ... Journal for Immunotherapy of Cancer 6, 1-10, 2018 | 65 | 2018 |
| Facilitated antigen presentation and its inhibition by blocking IgG antibodies depends on IgE repertoire complexity J Holm, N Willumsen, PA Würtzen, LH Christensen, K Lund Journal of Allergy and Clinical Immunology 127 (4), 1029-1037, 2011 | 63 | 2011 |
| High turnover of extracellular matrix reflected by specific protein fragments measured in serum is associated with poor outcomes in two metastatic breast cancer cohorts A Lipton, K Leitzel, SM Ali, HV Polimera, V Nagabhairu, E Marks, ... International journal of cancer 143 (11), 3027-3034, 2018 | 53 | 2018 |
| Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling JH Kristensen, MA Karsdal, JMB Sand, N Willumsen, C Diefenbach, ... BMC pulmonary medicine 15, 1-7, 2015 | 53 | 2015 |
| Clinical value of serum hyaluronan and propeptide of type III collagen in patients with pancreatic cancer IM Chen, N Willumsen, C Dehlendorff, AZ Johansen, BV Jensen, ... International Journal of Cancer 146 (10), 2913-2922, 2020 | 49 | 2020 |
| Type VIII collagen is elevated in diseases associated with angiogenesis and vascular remodeling NUB Hansen, N Willumsen, JMB Sand, L Larsen, MA Karsdal, ... Clinical biochemistry 49 (12), 903-908, 2016 | 49 | 2016 |
| Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction MIP Ramos, L Tian, EJ de Ruiter, C Song, A Paucarmayta, A Singh, ... Elife 10, e62927, 2021 | 48 | 2021 |
| Quantification of altered tissue turnover in a liquid biopsy: a proposed precision medicine tool to assess chronic inflammation and desmoplasia associated with a pro-cancerous … N Willumsen, LB Thomsen, CL Bager, C Jensen, MA Karsdal Cancer Immunology, Immunotherapy 67, 1-12, 2018 | 48 | 2018 |
| Collagen fragments quantified in serum as measures of desmoplasia associate with survival outcome in patients with advanced pancreatic cancer N Willumsen, SM Ali, K Leitzel, JJ Drabick, N Yee, HV Polimera, ... Scientific reports 9 (1), 19761, 2019 | 45 | 2019 |
| Cathepsin-S degraded decorin are elevated in fibrotic lung disorders–development and biological validation of a new serum biomarker SN Kehlet, CL Bager, N Willumsen, B Dasgupta, C Brodmerkel, M Curran, ... BMC pulmonary medicine 17, 1-10, 2017 | 41 | 2017 |
| Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer YL Liu, CL Bager, N Willumsen, D Ramchandani, N Kornhauser, L Ling, ... NPJ breast cancer 7 (1), 108, 2021 | 40 | 2021 |
| Matrix metalloprotease generated fragments of type VI collagen have serum biomarker potential in cancer–A proof of concept study N Willumsen, C Bager, MA Karsdal Translational Oncology 12 (5), 693-698, 2019 | 38 | 2019 |
| Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders JH Kristensen, L Larsen, B Dasgupta, C Brodmerkel, M Curran, ... Clinical biochemistry 48 (16-17), 1083-1088, 2015 | 35 | 2015 |
| Granzyme B degraded type IV collagen products in serum identify melanoma patients responding to immune checkpoint blockade C Jensen, D Sinkeviciute, DH Madsen, P Önnerfjord, M Hansen, ... Cancers 12 (10), 2786, 2020 | 34 | 2020 |
