Mitotane inhibits sterol-O-acyl transferase 1 triggering lipid-mediated endoplasmic reticulum stress and apoptosis in adrenocortical carcinoma cells S Sbiera, E Leich, G Liebisch, I Sbiera, A Schirbel, L Wiemer, S Matysik, ... Endocrinology 156 (11), 3895-3908, 2015 | 210 | 2015 |
Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas CL Ronchi, E Peverelli, S Herterich, I Weigand, G Mantovani, ... European journal of endocrinology 174 (3), 363-372, 2016 | 103 | 2016 |
Targeted molecular analysis in adrenocortical carcinomas: a strategy toward improved personalized prognostication J Lippert, S Appenzeller, R Liang, S Sbiera, S Kircher, B Altieri, I Nanda, ... The Journal of Clinical Endocrinology & Metabolism 103 (12), 4511-4523, 2018 | 100 | 2018 |
Driver mutations in USP8 wild-type Cushing’s disease S Sbiera, LG Perez-Rivas, L Taranets, I Weigand, J Flitsch, E Graf, ... Neuro-oncology 21 (10), 1273-1283, 2019 | 83 | 2019 |
Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma LS Landwehr, B Altieri, J Schreiner, I Sbiera, I Weigand, M Kroiss, ... Journal for ImmunoTherapy of Cancer 8 (1), 2020 | 75 | 2020 |
Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation CL Ronchi, G Di Dalmazi, S Faillot, S Sbiera, G Assié, I Weigand, ... The Journal of Clinical Endocrinology & Metabolism 101 (9), 3526-3538, 2016 | 66 | 2016 |
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction I Weigand, J Schreiner, F Röhrig, N Sun, LS Landwehr, H Urlaub, S Kendl, ... Cell death & disease 11 (3), 192, 2020 | 50 | 2020 |
Alterations in protein kinase a substrate specificity as a potential cause of cushing syndrome K Bathon, I Weigand, JT Vanselow, CL Ronchi, S Sbiera, A Schlosser, ... Endocrinology 160 (2), 447-459, 2019 | 38 | 2019 |
Impact of USP8 gene mutations on protein deregulation in Cushing disease I Weigand, L Knobloch, J Flitsch, W Saeger, CM Monoranu, K Höfner, ... The Journal of Clinical Endocrinology & Metabolism 104 (7), 2535-2546, 2019 | 37 | 2019 |
VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors F Röhrig, S Vorlová, H Hoffmann, M Wartenberg, FE Escorcia, S Keller, ... Oncogene 36 (1), 1-12, 2017 | 36 | 2017 |
The new genetic landscape of Cushing’s disease: deubiquitinases in the spotlight S Sbiera, M Kunz, I Weigand, T Deutschbein, T Dandekar, M Fassnacht Cancers 11 (11), 1761, 2019 | 33 | 2019 |
Sterol O-acyl transferase 1 as a prognostic marker of adrenocortical carcinoma AMF Lacombe, IC Soares, BMP Mariani, MY Nishi, JE Bezerra-Neto, ... Cancers 12 (1), 247, 2020 | 31 | 2020 |
A novel patient-derived cell line of adrenocortical carcinoma shows a pathogenic role of germline MUTYH mutation and high tumour mutational burden LS Landwehr, J Schreiner, S Appenzeller, S Kircher, S Herterich, S Sbiera, ... European journal of endocrinology 184 (6), 823-835, 2021 | 29 | 2021 |
Targeted gene expression profile reveals CDK4 as therapeutic target for selected patients with adrenocortical carcinoma R Liang, I Weigand, J Lippert, S Kircher, B Altieri, S Steinhauer, C Hantel, ... Frontiers in Endocrinology 11, 219, 2020 | 29 | 2020 |
Livin/BIRC7 expression as malignancy marker in adrenocortical tumors B Altieri, S Sbiera, S Della Casa, I Weigand, V Wild, S Steinhauer, ... Oncotarget 8 (6), 9323, 2017 | 29 | 2017 |
The new molecular landscape of Cushing's disease S Sbiera, T Deutschbein, I Weigand, M Reincke, M Fassnacht, B Allolio Trends in Endocrinology & Metabolism 26 (10), 573-583, 2015 | 28 | 2015 |
Expression of SOAT1 in adrenocortical carcinoma and response to mitotane monotherapy: an ENSAT multicenter study I Weigand, B Altieri, AMF Lacombe, V Basile, S Kircher, LS Landwehr, ... The Journal of Clinical Endocrinology & Metabolism 105 (8), 2642-2653, 2020 | 23 | 2020 |
Prognostic relevance of steroid sulfation in adrenocortical carcinoma revealed by molecular phenotyping using high-resolution mass spectrometry imaging N Sun, T Kunzke, S Sbiera, S Kircher, A Feuchtinger, M Aichler, ... Clinical Chemistry 65 (10), 1276-1286, 2019 | 23 | 2019 |
European Network for the Study of Adrenocortical Tumors (ENSAT). Genetic landscape of sporadic unilateral adrenocortical adenomas without PRKACA p. Leu206Arg mutation CL Ronchi, G Di Dalmazi, S Faillot, S Sbiera, G Assié, I Weigand, ... J Clin Endocrinol Metab 101 (9), 3526-38, 2016 | 21 | 2016 |
Mechanisms of aberrant PKA activation by Cα subunit mutations D Calebiro, K Bathon, I Weigand Hormone and Metabolic Research 49 (04), 307-314, 2017 | 16 | 2017 |