| TGR5-mediated bile acid sensing controls glucose homeostasis C Thomas, A Gioiello, L Noriega, A Strehle, J Oury, G Rizzo, ... Cell metabolism 10 (3), 167-177, 2009 | 1876 | 2009 |
| Targeting bile-acid signalling for metabolic diseases C Thomas, R Pellicciari, M Pruzanski, J Auwerx, K Schoonjans Nature reviews Drug discovery 7 (8), 678-693, 2008 | 1423 | 2008 |
| PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation P Bai, C Cantó, H Oudart, A Brunyánszki, Y Cen, C Thomas, H Yamamoto, ... Cell metabolism 13 (4), 461-468, 2011 | 867 | 2011 |
| TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading TWH Pols, M Nomura, T Harach, GL Sasso, MH Oosterveer, C Thomas, ... Cell metabolism 14 (6), 747-757, 2011 | 554 | 2011 |
| The metabolic footprint of aging in mice RH Houtkooper, C Argmann, SM Houten, C Cantó, EH Jeninga, ... Scientific reports 1 (1), 134, 2011 | 538 | 2011 |
| Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea H Sato, C Genet, A Strehle, C Thomas, A Lobstein, A Wagner, ... Biochemical and biophysical research communications 362 (4), 793-798, 2007 | 444 | 2007 |
| Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure− activity relationships, and molecular modeling studies H Sato, A Macchiarulo, C Thomas, A Gioiello, M Une, AF Hofmann, ... Journal of medicinal chemistry 51 (6), 1831-1841, 2008 | 337 | 2008 |
| Discovery of 6α-Ethyl-23(S)-methylcholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity R Pellicciari, A Gioiello, A Macchiarulo, C Thomas, E Rosatelli, B Natalini, ... Journal of medicinal chemistry 52 (24), 7958-7961, 2009 | 265 | 2009 |
| Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1 C Mataki, BC Magnier, SM Houten, JS Annicotte, C Argmann, C Thomas, ... Molecular and cellular biology 27 (23), 8330-8339, 2007 | 190 | 2007 |
| Enteroendocrine L cells sense LPS after gut barrier injury to enhance GLP-1 secretion LJ Lebrun, K Lenaerts, D Kiers, JPP de Barros, N Le Guern, J Plesnik, ... Cell reports 21 (5), 1160-1168, 2017 | 168 | 2017 |
| Bile acids and the membrane bile acid receptor TGR5—connecting nutrition and metabolism C Thomas, J Auwerx, K Schoonjans Thyroid 18 (2), 167-174, 2008 | 168 | 2008 |
| Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome proliferator-activated receptor-α-dependent JF Landrier, C Thomas, J Grober, H Duez, F Percevault, M Souidi, ... Journal of Biological Chemistry 279 (44), 45512-45518, 2004 | 134 | 2004 |
| Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis D Patoli, F Mignotte, V Deckert, A Dusuel, A Dumont, A Rieu, A Jalil, ... The Journal of clinical investigation 130 (11), 5858-5874, 2020 | 106 | 2020 |
| Role of TGR5 (GPBAR1) in liver disease V Keitel, D Häussinger Seminars in liver disease 38 (04), 333-339, 2018 | 83 | 2018 |
| Liver x receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: a key role for lysophosphatidylcholine acyltransferase 3 M Ishibashi, A Varin, R Filomenko, T Lopez, A Athias, P Gambert, ... Arteriosclerosis, thrombosis, and vascular biology 33 (6), 1171-1179, 2013 | 75 | 2013 |
| Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages: relevance in the context of atherosclerosis A Varin, C Thomas, M Ishibashi, L Ménégaut, T Gautier, A Trousson, ... Arteriosclerosis, thrombosis, and vascular biology 35 (6), 1357-1365, 2015 | 69 | 2015 |
| Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences C Thomas, JF Landrier, D Gaillard, J Grober, MC Monnot, A Athias, ... Gut 55 (9), 1321-1331, 2006 | 56 | 2006 |
| Probing the binding site of bile acids in TGR5 A Macchiarulo, A Gioiello, C Thomas, TWH Pols, R Nuti, C Ferrari, ... ACS medicinal chemistry letters 4 (12), 1158-1162, 2013 | 55 | 2013 |
| Liver‐specific ablation of Krüppel‐associated box–associated protein 1 in mice leads to male‐predominant hepatosteatosis and development of liver adenoma K Bojkowska, F Aloisio, M Cassano, A Kapopoulou, F Santoni de Sio, ... Hepatology 56 (4), 1279-1290, 2012 | 55 | 2012 |
| Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer … W Zeriouh, A Nani, M Belarbi, A Dumont, C de Rosny, I Aboura, ... PLoS One 12 (2), e0170823, 2017 | 52 | 2017 |
Johan AuwerxProfessor at the EPFLVerified email at epfl.ch
