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Jan Kihlberg
Jan Kihlberg
Professor i Organisk kemi
Verified email at kemi.uu.se
Title
Cited by
Cited by
Year
Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties?
F Giordanetto, J Kihlberg
Journal of medicinal chemistry 57 (2), 278-295, 2014
4742014
Oral druggable space beyond the rule of 5: insights from drugs and clinical candidates
BC Doak, B Over, F Giordanetto, J Kihlberg
Chemistry & biology 21 (9), 1115-1142, 2014
4512014
2-(Trimethylsilyl) ethyl glycosides. 3. Synthesis, anomeric deblocking, and transformation into 1, 2-trans 1-O-acyl sugars
K Jansson, S Ahlfors, T Frejd, J Kihlberg, G Magnusson, J Dahmen, ...
The Journal of Organic Chemistry 53 (24), 5629-5647, 1988
3851988
Structural basis of pilus subunit recognition by the PapD chaperone
MJ Kuehn, DJ Ogg, J Kihlberg, LN Slonim, K Flemmer, T Bergfors, ...
Science 262 (5137), 1234-1241, 1993
2871993
The PapG adhesin of uropathogenic Escherichia coli contains separate regions for receptor binding and for the incorporation into the pilus.
SJ Hultgren, F Lindberg, G Magnusson, J Kihlberg, JM Tennent, ...
Proceedings of the National Academy of Sciences 86 (12), 4357-4361, 1989
2351989
How beyond rule of 5 drugs and clinical candidates bind to their targets
BC Doak, J Zheng, D Dobritzsch, J Kihlberg
Journal of medicinal chemistry 59 (6), 2312-2327, 2016
2292016
Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis
J Bäcklund, S Carlsen, T Höger, B Holm, L Fugger, J Kihlberg, ...
Proceedings of the National Academy of Sciences 99 (15), 9960-9965, 2002
2292002
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen
NT Marcos, S Pinho, C Grandela, A Cruz, B Samyn-Petit, ...
Cancer research 64 (19), 7050-7057, 2004
2212004
Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen‐induced arthritis
A Corthay, J Bäcklund, J Broddefalk, E Michaëlsson, TJ Goldschmidt, ...
European journal of immunology 28 (8), 2580-2590, 1998
1991998
The in situ activation of thioglycosides with bromine: an improved glycosylation method
JO Kihlberg, DA Leigh, DR Bundle
The Journal of Organic Chemistry 55 (9), 2860-2863, 1990
1761990
Cell permeability beyond the rule of 5
P Matsson, BC Doak, B Over, J Kihlberg
Advanced Drug Delivery Reviews 101, 42-61, 2016
1732016
Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli
A Svensson, A Larsson, H Emtenäs, M Hedenström, T Fex, SJ Hultgren, ...
Chembiochem 2 (12), 915-918, 2001
1592001
The sesquiterpenes of Lactarius vellereus and their role in a proposed chemical defense system
O Sterner, R Bergman, J Kihlberg, B Wickberg
Journal of Natural Products 48 (2), 279-288, 1985
1591985
Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus
GE Soto, KW Dodson, D Ogg, C Liu, J Heuser, S Knight, J Kihlberg, ...
The EMBO journal 17 (21), 6155-6167, 1998
1441998
How big is too big for cell permeability?
P Matsson, J Kihlberg
Journal of Medicinal Chemistry 60 (5), 1662-1664, 2017
1372017
Structural and conformational determinants of macrocycle cell permeability
B Over, P Matsson, C Tyrchan, P Artursson, BC Doak, MA Foley, ...
Nature Chemical Biology 12 (12), 1065-1074, 2016
1322016
Impact of dynamically exposed polarity on permeability and solubility of chameleonic drugs beyond the rule of 5
M Rossi Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ...
Journal of Medicinal Chemistry 61 (9), 4189-4202, 2018
1272018
Preparation of building blocks for glycopeptide synthesis by glycosylation of Fmoc amino acids having unprotected carboxyl groups
LA Salvador, M Elofsson, J Kihlberg
Tetrahedron 51 (19), 5643-5656, 1995
1271995
Glycopeptides bind MHC molecules and elicit specific T cell responses.
CV Harding, J Kihlberg, M Elofsson, G Magnusson, ER Unanue
The Journal of Immunology 151 (5), 2419-2425, 1993
1251993
Building blocks for glycopeptide synthesis: Glycosylation of 3-mercaptopropionic acid and Fmoc amino acids with unprotected carboxyl groups
M Elofsson, B Walse, J Kihlberg
Tetrahedron letters 32 (51), 7613-7616, 1991
1241991
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