| The extracellular matrix modulates the metastatic journey FB Kai, AP Drain, VM Weaver Developmental cell 49 (3), 332-346, 2019 | 428 | 2019 |
| Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression O Maller, AP Drain, AS Barrett, S Borgquist, B Ruffell, I Zakharevich, ... Nature materials 20 (4), 548-559, 2021 | 149 | 2021 |
| Extracellular matrix remodeling and stiffening modulate tumor phenotype and treatment response JL Leight, AP Drain, VM Weaver Annual Review of Cancer Biology 1, 313-334, 2017 | 131 | 2017 |
| Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers K Takai, AP Drain, DA Lawson, LE Littlepage, M Karpuj, K Kessenbrock, ... Genes & development 32 (3-4), 244-257, 2018 | 64 | 2018 |
| Physical intimacy of breast cancer cells with mesenchymal stem cells elicits trastuzumab resistance through Src activation A Daverey, AP Drain, S Kidambi Scientific reports 5 (1), 13744, 2015 | 56 | 2015 |
| Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer AP Drain, N Zahir, JJ Northey, H Zhang, PJ Huang, O Maller, JN Lakins, ... Journal of Experimental Medicine 218 (5), e20191360, 2021 | 38 | 2021 |
| Inflammation promotes tumor aggression by stimulating stromal cell-dependent collagen crosslinking and stromal stiffening O Maller, AP Drain, AS Barrett, S Borgquist, B Ruffell, PT Thanh, ... bioRxiv, 2020.02. 13.948141, 2020 | 6 | 2020 |
| Matrix molecules and their ligands AP Drain, VM Weaver Principles of tissue engineering, 119-132, 2020 | 5 | 2020 |
| AFNT-212: A TRAC-knocked-in KRASG12D-specific TCR-T cell product enhanced with CD8αβ and a chimeric cytokine receptor for treatment of solid cancers A Drain, N Rouillard, N Swanson, M Canestraro, S Narayan, T Warner, ... Cancer Research 84 (6_Supplement), 9-9, 2024 | | 2024 |
| 355 Directing a high avidity KRAS G12D-specific TCR engineered with a CD8αβ co-receptor and chimeric cytokine receptor using non-viral knock-in enhances anti-tumor responses AP Drain, N Rouillard, N Swanson, S Narayan, T Warner, N Danek, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
| 1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in the TRAC locus outperforms lentiviral-based engineering of T cells S Narayan, AP Drain, N Swanson, N Rouillard, T Warner, N Danek, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
| Preclinical development of safe and effective T cell receptors specific for mutant KRAS G12D peptide C Black, J Parsons, A Thomas, AP Drain, S Narayan, J Francis, X He, ... Cancer Research 83 (7_Supplement), 1127-1127, 2023 | | 2023 |
| 342 KRAS G12V T cell receptor-engineered T cells expressing the durability FAS-41BB switch receptor exhibit a potent, persistent, coordinated CD4/CD8 anti-tumor response in … X He, M Hoffmann, J Liang, H Qu, A Drain, H Lam, S Oda, T Schmitt, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
| Multi-Arming and Regulator Dial Gene Circuits to Address Key Disease Challenges in HCC MG Ayala, M Hung, P Ramkumar, R Cottman, YY Chong, D Kaveri, ... MOLECULAR THERAPY 30 (4), 167-168, 2022 | | 2022 |
| Small Molecule-Regulated Gene Circuit for Controlling Cytokine Expression in Cell Therapies ME Hung, D Israni, H Li, YY Chong, P Ramkumar, A Drain, A Quach, ... MOLECULAR THERAPY 29 (4), 112-112, 2021 | | 2021 |
| Understanding Ecm Remodeling and Signaling in Breast Tumor Progression and Therapy Response A Drain University of California, San Francisco, 2020 | | 2020 |
| Abstract LB-055: Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive, basal-like breast cancer AP Drain, K Takai, DA Lawson, LE Littlepage, M Karpuj, K Kessenbrock, ... Cancer Research 78 (13_Supplement), LB-055-LB-055, 2018 | | 2018 |
| Abstract A098: A role for fibrosis in promoting pro-tumor immune response in breast cancer O Maller, L Cassereau, A Drain, B Ruffell, I Acerbi, M Broz, J Munson, ... Cancer Immunology Research 4 (11_Supplement), A098-A098, 2016 | | 2016 |
| ECM Stiffness Regulates Metabolism to Enable Mammary Tumor Invasion and Metastasis AP Drain, LD Cassereau, JK Mouw, JM Barnes, O Maller, JN Lakins, ... MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
| In Vitro Breast Tumor Model to Investigate the Role of Tumor Microenvironment in Disease Progression S Kidambi, A Daverey, A Drain | | |
Valerie M. WeaverProfessor of Surgery, Anatomy, Bioengineering and Therapeutic Sciences, University of CaliforniaBestätigte E-Mail-Adresse bei ucsf.edu
