| Formation, signaling and occurrence of specialized pro-resolving lipid mediators—what is the evidence so far? NH Schebb, H Kühn, AS Kahnt, KM Rund, VB O’Donnell, N Flamand, ... Frontiers in pharmacology 13, 838782, 2022 | 89 | 2022 |
| Lipoxin and resolvin biosynthesis is dependent on 5‐lipoxygenase activating protein C Lehmann, J Homann, AK Ball, R Blöcher, TK Kleinschmidt, ... The FASEB Journal 29 (12), 5029-5043, 2015 | 89 | 2015 |
| A dual modulator of farnesoid X receptor and soluble epoxide hydrolase to counter nonalcoholic steatohepatitis J Schmidt, M Rotter, T Weiser, S Wittmann, L Weizel, A Kaiser, J Heering, ... Journal of medicinal chemistry 60 (18), 7703-7724, 2017 | 75 | 2017 |
| 5-lipoxygenase: underappreciated role of a pro-inflammatory enzyme in tumorigenesis D Steinhilber, AS Fischer, J Metzner, SD Steinbrink, J Roos, M Ruthardt, ... Frontiers in pharmacology 1, 143, 2010 | 73 | 2010 |
| 5-lipoxygenase is a candidate target for therapeutic management of stem cell–like cells in acute myeloid leukemia J Roos, C Oancea, M Heinssmann, D Khan, H Held, AS Kahnt, R Capelo, ... Cancer Research 74 (18), 5244-5255, 2014 | 57 | 2014 |
| 5‐Lipoxygenase inhibitors induce potent anti‐proliferative and cytotoxic effects in human tumour cells independently of suppression of 5‐lipoxygenase activity AS Fischer, J Metzner, SD Steinbrink, S Ulrich, C Angioni, G Geisslinger, ... British journal of pharmacology 161 (4), 936-949, 2010 | 56 | 2010 |
| N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators R Blöcher, C Lamers, SK Wittmann, D Merk, M Hartmann, L Weizel, ... Journal of medicinal chemistry 59 (1), 61-81, 2016 | 51 | 2016 |
| Characterisation of Taxlllaids A–G; Natural Products from Xenorhabdus indica M Kronenwerth, KAJ Bozhüyük, AS Kahnt, D Steinhilber, S Gaudriault, ... Chemistry–A European Journal 20 (52), 17478-17487, 2014 | 42 | 2014 |
| Long-term stimulation of toll-like receptor-2 and-4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages R Ebert, R Cumbana, C Lehmann, L Kutzner, A Toewe, N Ferreirós, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 37 | 2020 |
| Boosting anti-inflammatory potency of zafirlukast by designed polypharmacology S Schierle, C Flauaus, P Heitel, S Willems, J Schmidt, A Kaiser, L Weizel, ... Journal of Medicinal Chemistry 61 (13), 5758-5764, 2018 | 36 | 2018 |
| Beyond leukotriene formation—The noncanonical functions of 5-lipoxygenase AK Häfner, AS Kahnt, D Steinhilber Prostaglandins & other lipid mediators 142, 24-32, 2019 | 33 | 2019 |
| Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE2 synthesis by inhibiting mPGES-1 activity AS Kahnt, F Rörsch, O Diehl, B Hofmann, C Lehmann, SD Steinbrink, ... Biochemical Pharmacology 86 (2), 286-296, 2013 | 32 | 2013 |
| Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations SD Steinbrink, C Pergola, U Bühring, S George, J Metzner, AS Fischer, ... Cellular and molecular life sciences 67, 797-806, 2010 | 32 | 2010 |
| Molecular characterization of EP6—A novel imidazo [1, 2-a] pyridine based direct 5-lipoxygenase inhibitor JM Wisniewska, CB Rödl, AS Kahnt, E la Buscató, S Ulrich, Y Tanrikulu, ... Biochemical pharmacology 83 (2), 228-240, 2012 | 30 | 2012 |
| A pirinixic acid derivative (LP105) inhibits murine 5‐lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm M Revermann, A Mieth, L Popescu, A Paulke, M Wurglics, M Pellowska, ... British journal of pharmacology 163 (8), 1721-1732, 2011 | 29 | 2011 |
| l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ L Gellrich, P Heitel, J Heering, W Kilu, J Pollinger, T Goebel, A Kahnt, ... Journal of Medicinal Chemistry 63 (13), 6727-6740, 2020 | 28 | 2020 |
| Tandem benzophenone amino pyridines, potent and selective inhibitors of human leukotriene C4 synthase TK Kleinschmidt, M Haraldsson, D Basavarajappa, E Lundeberg, ... Journal of Pharmacology and Experimental Therapeutics 355 (1), 108-116, 2015 | 28 | 2015 |
| Cellular analysis of the histamine H4 receptor in human myeloid cells R Capelo, C Lehmann, K Ahmad, R Snodgrass, O Diehl, J Ringleb, ... Biochemical pharmacology 103, 74-84, 2016 | 25 | 2016 |
| Pan-SMARCA/PB1 bromodomain inhibitors and their role in regulating adipogenesis M Wanior, F Preuss, X Ni, A Krämer, S Mathea, T Göbel, ... Journal of medicinal chemistry 63 (23), 14680-14699, 2020 | 23 | 2020 |
| Formation of lipoxins and resolvins in human leukocytes AS Kahnt, NH Schebb, D Steinhilber Prostaglandins & Other Lipid Mediators 166, 106726, 2023 | 21 | 2023 |
Dieter SteinhilberProfessor für Pharmazeutische ChemieBestätigte E-Mail-Adresse bei em.uni-frankfurt.de
