Harry Leitch
Harry Leitch
Great Ormond Street Hospital
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene
X D'Anglemont De Tassigny, LA Fagg, JPC Dixon, K Day, HG Leitch, ...
Proceedings of the National Academy of Sciences 104 (25), 10714, 2007
A unique gene regulatory network resets the human germline epigenome for development
WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ...
Cell 161 (6), 1453-1467, 2015
Naive pluripotency is associated with global DNA hypomethylation
HG Leitch, KR McEwen, A Turp, V Encheva, T Carroll, N Grabole, ...
Nature structural & molecular biology 20 (3), 311-316, 2013
Hallmarks of pluripotency
A De Los Angeles, F Ferrari, R Xi, Y Fujiwara, N Benvenisty, H Deng, ...
Nature 525 (7570), 469-478, 2015
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte
PWS Hill, HG Leitch, CE Requena, Z Sun, R Amouroux, M Roman-Trufero, ...
Nature 555 (7696), 392-396, 2018
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
GC Le Bin, S Muñoz-Descalzo, A Kurowski, H Leitch, X Lou, W Mansfield, ...
Development 141 (5), 1001-1010, 2014
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
N Grabole, J Tischler, JA Hackett, S Kim, F Tang, HG Leitch, ...
EMBO reports 14 (7), 629-637, 2013
Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
HG Leitch, K Blair, W Mansfield, H Ayetey, P Humphreys, J Nichols, ...
Development 137 (14), 2279-2287, 2010
Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency
JA Hackett, S Dietmann, K Murakami, TA Down, HG Leitch, MA Surani
Stem cell reports 1 (6), 518-531, 2013
Primordial germ-cell development and epigenetic reprogramming in mammals.
HG Leitch, WW Tang, MA Surani
Current topics in developmental biology 104, 149-187, 2013
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion
FM Piccolo, H Bagci, KE Brown, D Landeira, J Soza-Ried, A Feytout, ...
Molecular cell 49 (6), 1023-1033, 2013
Reconstitution of the oocyte transcriptional network with transcription factors
N Hamazaki, H Kyogoku, H Araki, F Miura, C Horikawa, N Hamada, ...
Nature 589 (7841), 264-269, 2021
Defined conditions for propagation and manipulation of mouse embryonic stem cells
C Mulas, T Kalkan, F von Meyenn, HG Leitch, J Nichols, A Smith
Development 146 (6), dev173146, 2019
The mammalian germline as a pluripotency cycle
HG Leitch, A Smith
Development 140 (12), 2495-2501, 2013
Rebuilding pluripotency from primordial germ cells
HG Leitch, J Nichols, P Humphreys, C Mulas, G Martello, C Lee, K Jones, ...
Stem cell reports 1 (1), 66-78, 2013
Esrrb complementation rescues development of Nanog-null germ cells
M Zhang, HG Leitch, WWC Tang, N Festuccia, E Hall-Ponsele, J Nichols, ...
Cell reports 22 (2), 332-339, 2018
SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA
N Cvetesic, HG Leitch, M Borkowska, F Müller, P Carninci, P Hajkova, ...
Genome Research 28 (12), 1943-1956, 2018
The impact of culture on epigenetic properties of pluripotent stem cells and pre-implantation embryos
KR McEwen, HG Leitch, R Amouroux, P Hajkova
Biochemical Society Transactions 41 (3), 711-719, 2013
Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells
K Blair, HG Leitch, W Mansfield, CÉ Dumeau, P Humphreys, AG Smith
Biology Open 1 (1), 58-65, 2011
The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells
S Bao, HG Leitch, A Gillich, J Nichols, F Tang, S Kim, C Lee, T Zwaka, X Li, ...
Cell Stem Cell 11 (1), 110-117, 2012
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