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Melanie J Scott
Melanie J Scott
Bestätigte E-Mail-Adresse bei upmc.edu - Startseite
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Zitiert von
Jahr
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13162*2021
The endotoxin delivery protein HMGB1 mediates caspase-11-dependent lethality in sepsis
M Deng, Y Tang, W Li, X Wang, R Zhang, X Zhang, X Zhao, J Liu, C Tang, ...
Immunity 49 (4), 740-753. e7, 2018
4542018
Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis
J Xu, Y Jiang, J Wang, X Shi, Q Liu, Z Liu, Y Li, MJ Scott, G Xiao, S Li, ...
Cell Death & Differentiation 21 (8), 1229-1239, 2014
2232014
Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type–specific functions of TLR4 during Sepsis
M Deng, MJ Scott, P Loughran, G Gibson, C Sodhi, S Watkins, D Hackam, ...
The Journal of Immunology 190 (10), 5152-5160, 2013
2072013
Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14
S Kim, SY Kim, JP Pribis, M Lotze, KP Mollen, R Shapiro, P Loughran, ...
Molecular Medicine 19, 88-98, 2013
2032013
Inflammasome and autophagy regulation: a two-way street
Q Sun, J Fan, TR Billiar, MJ Scott
Molecular Medicine 23, 188-195, 2017
1782017
Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells
M Xiang, X Shi, Y Li, J Xu, L Yin, G Xiao, MJ Scott, TR Billiar, MA Wilson, ...
The Journal of Immunology 187 (9), 4809-4817, 2011
1742011
Factors predisposing to bacterial invasion and infection
M Heinzelmann, M Scott, T Lam
The American journal of surgery 183 (2), 179-190, 2002
1432002
Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling
N Obermajer, JL Wong, RP Edwards, K Chen, M Scott, S Khader, JK Kolls, ...
Journal of Experimental Medicine 210 (7), 1433-1445, 2013
1392013
Location is the key to function: HMGB1 in sepsis and trauma-induced inflammation
M Deng, MJ Scott, J Fan, TR Billiar
Journal of leukocyte biology 106 (1), 161-169, 2019
1362019
β2-Integrin-induced p38 MAPK Activation Is a Key Mediator in the CD14/TLR4/MD2-dependent Uptake of Lipopolysaccharide by Hepatocytes∗
MJ Scott, TR Billiar
Journal of Biological Chemistry 283 (43), 29433-29446, 2008
1192008
Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study
CW Seymour, S Yende, MJ Scott, J Pribis, RP Mohney, LN Bell, YF Chen, ...
Intensive care medicine 39, 1423-1434, 2013
1182013
Immune‐Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury
Z Yi, M Deng, MJ Scott, G Fu, PA Loughran, Z Lei, S Li, P Sun, C Yang, ...
Hepatology 72 (4), 1394-1411, 2020
1172020
Caspase-1 as a multifunctional inflammatory mediator: noncytokine maturation roles
Q Sun, MJ Scott
Journal of Leucocyte Biology 100 (5), 961-967, 2016
1142016
LPS induces active HMGB1 release from hepatocytes into exosomes through the coordinated activities of TLR4 and caspase-11/GSDMD signaling
W Li, M Deng, PA Loughran, M Yang, M Lin, C Yang, W Gao, S Jin, S Li, ...
Frontiers in immunology 11, 229, 2020
1012020
Jaks, STATs, cytokines, and sepsis
MJ Scott, CJ Godshall, WG Cheadle
Clinical and Vaccine Immunology 9 (6), 1153-1159, 2002
982002
Interleukin-10 suppresses natural killer cell but not natural killer T cell activation during bacterial infection
MJ Scott, JJ Hoth, M Turina, DR Woods, WG Cheadle
Cytokine 33 (2), 79-86, 2006
942006
Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress
Q Sun, W Gao, P Loughran, R Shapiro, J Fan, TR Billiar, MJ Scott
Journal of Biological Chemistry 288 (22), 15947-15958, 2013
932013
Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production
MJ Scott, C Chen, Q Sun, TR Billiar
Journal of hepatology 53 (4), 693-701, 2010
902010
cGAS-mediated autophagy protects the liver from ischemia-reperfusion injury independently of STING
Z Lei, M Deng, Z Yi, Q Sun, RA Shapiro, H Xu, T Li, PA Loughran, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 314 (6 …, 2018
892018
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