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Guanglei Zhuang
Guanglei Zhuang
Shanghai Jiao Tong University
Bestätigte E-Mail-Adresse bei renji.com - Startseite
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Zitiert von
Zitiert von
Jahr
Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells
HJ Lee, G Zhuang, Y Cao, P Du, HJ Kim, J Settleman
Cancer cell 26 (2), 207-221, 2014
5472014
Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway
G Zhuang, X Wu, Z Jiang, I Kasman, J Yao, Y Guan, J Oeh, Z Modrusan, ...
The EMBO journal 31 (17), 3513-3523, 2012
5152012
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
AS Chung, X Wu, G Zhuang, H Ngu, I Kasman, J Zhang, JM Vernes, ...
Nature medicine 19 (9), 1114-1123, 2013
4812013
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling
DM Brantley-Sieders, G Zhuang, D Hicks, WB Fang, Y Hwang, JMM Cates, ...
The Journal of clinical investigation 118 (1), 64-78, 2008
3102008
Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy
G Zhuang, DM Brantley-Sieders, D Vaught, J Yu, L Xie, S Wells, ...
Cancer research 70 (1), 299-308, 2010
2632010
Molecular targeted therapies elicit concurrent apoptotic and GSDME-dependent pyroptotic tumor cell death
H Lu, S Zhang, J Wu, M Chen, MC Cai, Y Fu, W Li, J Wang, X Zhao, Z Yu, ...
Clinical Cancer Research 24 (23), 6066-6077, 2018
2092018
Impaired tumor microenvironment in EphA2‐deficient mice inhibits tumor angiogenesis and metastatic progression
DM Brantley‐Sieders, WB Fang, DJ Hicks, G Zhuang, Y Shyr, J Chen
The FASEB journal 19 (13), 1884-1886, 2005
2002005
Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation
G Zhuang, S Hunter, Y Hwang, J Chen
Journal of Biological Chemistry 282 (4), 2683-2694, 2007
1672007
Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis
SG Hunter, G Zhuang, D Brantley-Sieders, W Swat, CW Cowan, J Chen
Molecular and cellular biology 26 (13), 4830-4842, 2006
1602006
Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism
WB Fang, RC Ireton, G Zhuang, T Takahashi, A Reynolds, J Chen
Journal of cell science 121 (3), 358-368, 2008
1502008
Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells
Y Sun, A Daemen, G Hatzivassiliou, D Arnott, C Wilson, G Zhuang, M Gao, ...
Cancer & metabolism 2, 1-14, 2014
1392014
Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
Y Jing, J Liu, Y Ye, L Pan, H Deng, Y Wang, Y Yang, L Diao, SH Lin, ...
Nature communications 11 (1), 4946, 2020
1342020
Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment
VT Phan, X Wu, JH Cheng, RX Sheng, AS Chung, G Zhuang, C Tran, ...
Proceedings of the National Academy of Sciences 110 (15), 6079-6084, 2013
1222013
Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy
J Yao, X Wu, G Zhuang, IM Kasman, T Vogt, V Phan, M Shibuya, ...
Proceedings of the National Academy of Sciences 108 (28), 11590-11595, 2011
1142011
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors
S Zhang, M Zhang, Y Jing, X Yin, P Ma, Z Zhang, X Wang, W Di, ...
Nature communications 9 (1), 215, 2018
1092018
Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors
AS Chung, M Kowanetz, X Wu, G Zhuang, H Ngu, D Finkle, L Komuves, ...
The Journal of pathology 227 (4), 404-416, 2012
972012
BET bromodomain inhibition as a therapeutic strategy in ovarian cancer by downregulating FoxM1
Z Zhang, P Ma, Y Jing, Y Yan, MC Cai, M Zhang, S Zhang, H Peng, ZL Ji, ...
Theranostics 6 (2), 219, 2016
922016
Induction of Bv8 expression by granulocyte colony-stimulating factor in CD11b+ Gr1+ cells: key role of Stat3 signaling
X Qu, G Zhuang, L Yu, G Meng, N Ferrara
Journal of Biological Chemistry 287 (23), 19574-19584, 2012
912012
Phosphoproteomic analysis implicates the mTORC2-FoxO1 axis in VEGF signaling and feedback activation of receptor tyrosine kinases
G Zhuang, K Yu, Z Jiang, A Chung, J Yao, C Ha, K Toy, R Soriano, ...
Science signaling 6 (271), ra25-ra25, 2013
832013
Preclinical efficacy and molecular mechanism of targeting CDK7-dependent transcriptional addiction in ovarian cancer
Z Zhang, H Peng, X Wang, X Yin, P Ma, Y Jing, MC Cai, J Liu, M Zhang, ...
Molecular cancer therapeutics 16 (9), 1739-1750, 2017
732017
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