Stephan A. Sieber
Stephan A. Sieber
Professor of Organic Chemistry, TU Munich
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Zitiert von
Zitiert von
Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics
SA Sieber, MA Marahiel
Chemical reviews 105 (2), 715-738, 2005
Proteomic profiling of metalloprotease activities with cocktails of active-site probes
SA Sieber, S Niessen, HS Hoover, BF Cravatt
Nature chemical biology 2 (5), 274-281, 2006
Chemical proteomics approaches for identifying the cellular targets of natural products
MH Wright, SA Sieber
Natural product reports 33 (5), 681-708, 2016
Electrophilic natural products and their biological targets
M Gersch, J Kreuzer, SA Sieber
Natural product reports 29 (6), 659-682, 2012
β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors of Staphylococcus aureus
T Böttcher, SA Sieber
Journal of the American Chemical Society 130 (44), 14400-14401, 2008
The microstructure and micromechanics of the tendon–bone insertion
L Rossetti, LA Kuntz, E Kunold, J Schock, KW Müller, H Grabmayr, ...
Nature materials 16 (6), 664-670, 2017
Natural products and their biological targets: proteomic and metabolomic labeling strategies
T Böttcher, M Pitscheider, SA Sieber
Angewandte Chemie International Edition 49 (15), 2680-2698, 2010
Substrate transfer from the chaperone Hsp70 to Hsp90
H Wegele, SK Wandinger, AB Schmid, J Reinstein, J Buchner
Journal of molecular biology 356 (3), 802-811, 2006
Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs
A Javaheri, T Kruse, K Moonens, R Mejías-Luque, A Debraekeleer, ...
Nature microbiology 2 (1), 1-13, 2016
Learning from Nature's Drug Factories: Nonribosomal Synthesisof MacrocyclicPeptides
SA Sieber, MA Marahiel
Journal of bacteriology 185 (24), 7036-7043, 2003
β‐Lactones as Privileged Structures for the Active‐Site Labeling of Versatile Bacterial Enzyme Classes
T Böttcher, SA Sieber
Angewandte Chemie International Edition 47 (24), 4600-4603, 2008
Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics
J Grünewald, SA Sieber, C Mahlert, U Linne, MA Marahiel
Journal of the American Chemical Society 126 (51), 17025-17031, 2004
Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase
CC Tseng, SD Bruner, RM Kohli, MA Marahiel, CT Walsh, SA Sieber
Biochemistry 41 (45), 13350-13359, 2002
β-Lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence
I Staub, SA Sieber
Journal of the American Chemical Society 130 (40), 13400-13409, 2008
Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras‐signaling modulators palmostatin B and M
M Rusch, TJ Zimmermann, M Bürger, FJ Dekker, K Görmer, G Triola, ...
Angewandte Chemie 123 (42), 10012-10016, 2011
Chirality of peptide bond-forming condensation domains in nonribosomal peptide synthetases: the C5 domain of tyrocidine synthetase is a DCL catalyst
SL Clugston, SA Sieber, MA Marahiel, CT Walsh
Biochemistry 42 (41), 12095-12104, 2003
Electron‐Beam Induced Growth of Bare Silver Nanowires from Zeolite Crystallites
MJ Edmondson, W Zhou, SA Sieber, IP Jones, I Gameson, PA Anderson, ...
Advanced Materials 13 (21), 1608-1611, 2001
AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control
M Gersch, K Famulla, M Dahmen, C Göbl, I Malik, K Richter, VS Korotkov, ...
Nature communications 6 (1), 1-12, 2015
Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells
J Eirich, R Orth, SA Sieber
Journal of the American Chemical Society 133 (31), 12144-12153, 2011
Thinking outside the box—novel antibacterials to tackle the resistance crisis
M Lakemeyer, W Zhao, FA Mandl, P Hammann, SA Sieber
Angewandte Chemie International Edition 57 (44), 14440-14475, 2018
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