| Treg cell function in rheumatoid arthritis is compromised by CTLA‐4 promoter methylation resulting in a failure to activate the indoleamine 2, 3‐dioxygenase pathway AP Cribbs, A Kennedy, H Penn, JE Read, P Amjadi, P Green, K Syed, ... Arthritis & rheumatology 66 (9), 2344-2354, 2014 | 164 | 2014 |
| Methotrexate restores regulatory T cell function through demethylation of the FoxP3 upstream enhancer in patients with rheumatoid arthritis AP Cribbs, A Kennedy, H Penn, P Amjadi, P Green, JE Read, F Brennan, ... Arthritis & rheumatology 67 (5), 1182-1192, 2015 | 162 | 2015 |
| Simplified production and concentration of lentiviral vectors to achieve high transduction in primary human T cells AP Cribbs, A Kennedy, B Gregory, FM Brennan BMC biotechnology 13, 1-8, 2013 | 160 | 2013 |
| A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 159 | 2022 |
| An essential role for the Zn2+ transporter ZIP7 in B cell development C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ... Nature immunology 20 (3), 350-361, 2019 | 114 | 2019 |
| Indoleamine 2, 3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development JE Cole, N Astola, AP Cribbs, ME Goddard, I Park, P Green, AH Davies, ... Proceedings of the National Academy of Sciences 112 (42), 13033-13038, 2015 | 96 | 2015 |
| Focus: Genome editing: Science and bioethics of CRISPR-Cas9 gene editing: An analysis towards separating facts and fiction AP Cribbs, SMW Perera The Yale journal of biology and medicine 90 (4), 625, 2017 | 91 | 2017 |
| Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming A Ebrahimi, K Sevinç, G Gürhan Sevinç, AP Cribbs, M Philpott, F Uyulur, ... Nature chemical biology 15 (5), 519-528, 2019 | 84 | 2019 |
| Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells A Cribbs, ES Hookway, G Wells, M Lindow, S Obad, H Oerum, RK Prinjha, ... Journal of Biological Chemistry 293 (7), 2422-2437, 2018 | 83 | 2018 |
| Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells PA Beavis, B Gregory, P Green, AP Cribbs, A Kennedy, P Amjadi, ... Proceedings of the national academy of sciences 108 (40), 16717-16722, 2011 | 74 | 2011 |
| Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism AP Cribbs, S Terlecki-Zaniewicz, M Philpott, J Baardman, D Ahern, ... Proceedings of the National Academy of Sciences 117 (11), 6056-6066, 2020 | 70 | 2020 |
| A novel upstream enhancer of FOXP3, sensitive to methylation‐induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells A Kennedy, EM Schmidt, AP Cribbs, H Penn, P Amjadi, K Syed, JE Read, ... European journal of immunology 44 (10), 2968-2978, 2014 | 63 | 2014 |
| Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study M Guo, C Bafligil, T Tapmeier, C Hubbard, S Manek, C Shang, ... BMC medicine 18, 1-16, 2020 | 61 | 2020 |
| Hypoxia induces transcriptional and translational downregulation of the type I IFN pathway in multiple cancer cell types A Miar, E Arnaiz, E Bridges, S Beedie, AP Cribbs, DJ Downes, ... Cancer research 80 (23), 5245-5256, 2020 | 61 | 2020 |
| Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq M Philpott, J Watson, A Thakurta, T Brown Jr, T Brown Sr, U Oppermann, ... Nature biotechnology 39 (12), 1517-1520, 2021 | 58 | 2021 |
| Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300 LM Williams, FE McCann, MA Cabrita, T Layton, A Cribbs, B Knezevic, ... Proceedings of the National Academy of Sciences 117 (34), 20753-20763, 2020 | 58 | 2020 |
| Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications A Cribbs, M Feldmann, U Oppermann Therapeutic advances in musculoskeletal disease 7 (5), 206-219, 2015 | 49 | 2015 |
| A chemical probe for tudor domain protein Spindlin1 to investigate chromatin function V Fagan, C Johansson, C Gileadi, O Monteiro, JE Dunford, R Nibhani, ... Journal of medicinal chemistry 62 (20), 9008-9025, 2019 | 36 | 2019 |
| Interleukin-17A Causes Osteoarthritis-Like Transcriptional Changes in Human Osteoarthritis-Derived Chondrocytes and Synovial Fibroblasts In Vitro JY Mimpen, MJ Baldwin, AP Cribbs, M Philpott, AJ Carr, SG Dakin, ... Frontiers in immunology 12, 676173, 2021 | 35 | 2021 |
| Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death L Cottone, AP Cribbs, G Khandelwal, G Wells, L Ligammari, M Philpott, ... Cancer Research 80 (20), 4540-4551, 2020 | 34 | 2020 |
