| Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells T Sparwasser, ES Koch, RM Vabulas, K Heeg, GB Lipford, JW Ellwart, ... European journal of immunology 28 (6), 2045-2054, 1998 | 1047 | 1998 |
| CpG‐DNA‐specific activation of antigen‐presenting cells requires stress kinase activity and is preceded by non‐specific endocytosis and endosomal maturation H Häcker, H Mischak, T Miethke, S Liptay, R Schmid, T Sparwasser, ... The EMBO journal, 1998 | 881 | 1998 |
| T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor. T Miethke, C Wahl, K Heeg, B Echtenacher, PH Krammer, H Wagner The Journal of experimental medicine 175 (1), 91-98, 1992 | 732 | 1992 |
| Cutting edge: CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis S Zimmermann, O Egeter, S Hausmann, GB Lipford, M Röcken, ... The Journal of Immunology 160 (8), 3627-3630, 1998 | 630 | 1998 |
| Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock T Sparwasser, T Miethke, G Lipford, A Erdmann, H Häcker, K Heeg, ... European journal of immunology 27 (7), 1671-1679, 1997 | 553 | 1997 |
| CpG‐containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants GB Lipford, M Bauer, C Blank, R Reiter, H Wagner, K Heeg European journal of immunology 27 (9), 2340-2344, 1997 | 529 | 1997 |
| Bacterial DNA causes septic shock T Sparwasser, T Miethke, G Lipford, K Borschert, H Häcker, K Heeg, ... Nature 386 (6623), 336-337, 1997 | 528 | 1997 |
| Distinct mechanisms of immunosuppression as a consequence of major surgery T Hensler, H Hecker, K Heeg, CD Heidecke, H Bartels, W Barthlen, ... Infection and immunity 65 (6), 2283-2291, 1997 | 465 | 1997 |
| PD‐L1 expression on tolerogenic APCs is controlled by STAT‐3 SJ Wölfle, J Strebovsky, H Bartz, A Sähr, C Arnold, C Kaiser, AH Dalpke, ... European journal of immunology 41 (2), 413-424, 2011 | 372 | 2011 |
| Immunostimulatory DNA: sequence‐dependent production of potentially harmful or useful cytokines GB Lipford, T Sparwasser, M Bauer, S Zimmermann, ES Koch, K Heeg, ... European journal of immunology 27 (12), 3420-3426, 1997 | 359 | 1997 |
| IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice T Biedermann, S Zimmermann, H Himmelrich, A Gumy, O Egeter, ... Nature immunology 2 (11), 1054-1060, 2001 | 345 | 2001 |
| Suppressor of Cytokine Signaling (SOCS) Proteins Indirectly Regulate Toll-like Receptor Signaling in Innate Immune Cells*♦ A Baetz, M Frey, K Heeg, AH Dalpke Journal of Biological Chemistry 279 (52), 54708-54715, 2004 | 340 | 2004 |
| Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs AH Dalpke, S Opper, S Zimmermann, K Heeg The Journal of Immunology 166 (12), 7082-7089, 2001 | 320 | 2001 |
| The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype P Ahmad-Nejad, S Mrabet-Dahbi, K Breuer, M Klotz, T Werfel, U Herz, ... Journal of Allergy and Clinical Immunology 113 (3), 565-567, 2004 | 311 | 2004 |
| T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice H Wagner, C Hardt, K Heeg, M Röllinghoff, K Pfizenmaier Nature 284 (5753), 278-280, 1980 | 303 | 1980 |
| T‐T cell interactions during cytotoxic T lymphocyte (CTL) responses: T cell derived helper factor (interleukin 2) as a probe to analyze CTL responsiveness and thymic maturation … H Wagner, C Hardt, K Heeg, K Pfizenmaier, W Solbach, R Bartlett, ... Immunological Reviews 51 (1), 215-255, 1980 | 268 | 1980 |
| Pharmaceutical compositions comprising a polynucleotide and optionally an antigen especially for vaccination H Wagner, G Lipford, K Heeg US Patent 7,001,890, 2006 | 267 | 2006 |
| Pharmaceutical compositions comprising a polynucleotide and optionally an antigen especially for vaccination H Wagner, G Lipford, K Heeg US Patent 7,001,890, 2006 | 260 | 2006 |
| Activation of toll-like receptor 9 by DNA from different bacterial species A Dalpke, J Frank, M Peter, K Heeg Infection and immunity 74 (2), 940-946, 2006 | 252 | 2006 |
| Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells AK Mayer, M Muehmer, J Mages, K Gueinzius, C Hess, K Heeg, R Bals, ... The Journal of Immunology 178 (5), 3134-3142, 2007 | 236 | 2007 |
