| Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ... Frontiers in Physiology 8, 616, 2017 | 168 | 2017 |
| Improving the in silico assessment of proarrhythmia risk by combining hERG (human ether-à-go-go-related gene) channel–drug binding kinetics and multichannel pharmacology Z Li, S Dutta, J Sheng, PN Tran, W Wu, K Chang, T Mdluli, DG Strauss, ... Circulation: Arrhythmia and Electrophysiology 10 (2), e004628, 2017 | 160 | 2017 |
| Calcium-channel number critically influences synaptic strength and plasticity at the active zone J Sheng, L He, H Zheng, L Xue, F Luo, W Shin, T Sun, T Kuner, DT Yue, ... Nature neuroscience 15 (7), 998-1006, 2012 | 150 | 2012 |
| Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative Z Li, BJ Ridder, X Han, WW Wu, J Sheng, PN Tran, M Wu, A Randolph, ... Clinical Pharmacology & Therapeutics 105 (2), 466-475, 2019 | 135 | 2019 |
| Actin is crucial for all kinetically distinguishable forms of endocytosis at synapses XS Wu, SH Lee, J Sheng, Z Zhang, WD Zhao, D Wang, Y Jin, P Charnay, ... Neuron 92 (5), 1020-1035, 2016 | 110 | 2016 |
| Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ... Frontiers in physiology 8, 917, 2017 | 82 | 2017 |
| Apomorphine‐induced activation of dopamine receptors modulates FGF‐2 expression in astrocytic cultures and promotes survival of dopaminergic neurons A Li, H Guo, X Luo, J Sheng, S Yang, Y Yin, J Zhou, J Zhou, A Li, H Guo, ... The FASEB journal 20 (8), 1263-1265, 2006 | 82 | 2006 |
| Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles HC Chiang, W Shin, WD Zhao, E Hamid, J Sheng, M Baydyuk, PJ Wen, ... Nature communications 5 (1), 3356, 2014 | 81 | 2014 |
| Cystatin C prevents degeneration of rat nigral dopaminergic neurons: in vitro and in vivo studies L Xu, J Sheng, Z Tang, X Wu, Y Yu, H Guo, Y Shen, C Zhou, L Paraoan, ... Neurobiology of disease 18 (1), 152-165, 2005 | 79 | 2005 |
| α-Synuclein mutation inhibits endocytosis at mammalian central nerve terminals J Xu, XS Wu, J Sheng, Z Zhang, HY Yue, L Sun, C Sgobio, X Lin, S Peng, ... Journal of Neuroscience 36 (16), 4408-4414, 2016 | 69 | 2016 |
| Plasticizer interaction with the heart: chemicals used in plastic medical devices can interfere with cardiac electrophysiology R Jaimes III, D McCullough, B Siegel, L Swift, D McInerney, J Hiebert, ... Circulation: Arrhythmia and Electrophysiology 12 (7), e007294, 2019 | 48 | 2019 |
| Voltage-Dependent Calcium Channels at the Plasma Membrane, but Not Vesicular Channels, Couple Exocytosis to Endocytosis L Xue, Z Zhang, BD McNeil, F Luo, XS Wu, J Sheng, W Shin, LG Wu Cell Reports, 2012 | 44 | 2012 |
| A temperature-dependent in silico model of the human ether-à-go-go-related (hERG) gene channel Z Li, S Dutta, J Sheng, PN Tran, W Wu, T Colatsky Journal of pharmacological and toxicological methods 81, 233-239, 2016 | 42 | 2016 |
| Bystin-like protein is upregulated in hepatocellular carcinoma and required for nucleologenesis in cancer cell proliferation H Wang, W Xiao, Q Zhou, Y Chen, S Yang, J Sheng, Y Yin, J Fan, J Zhou Cell research 19 (10), 1150-1164, 2009 | 39 | 2009 |
| Bystin as a novel marker for reactive astrocytes in the adult rat brain following injury J Sheng, S Yang, L Xu, C Wu, X Wu, A Li, Y Yu, H Ni, M Fukuda, J Zhou European Journal of Neuroscience 20 (4), 873-884, 2004 | 39 | 2004 |
| A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 394, 114961, 2020 | 33 | 2020 |
| Bisphenol S and bisphenol F are less disruptive to cardiac electrophysiology, as compared with bisphenol A TM Prudencio, LM Swift, D Guerrelli, B Cooper, M Reilly, N Ciccarelli, ... Toxicological Sciences 183 (1), 214-226, 2021 | 29 | 2021 |
| Most vesicles in a central nerve terminal participate in recycling L Xue, J Sheng, XS Wu, W Wu, F Luo, W Shin, HC Chiang, LG Wu Journal of Neuroscience 33 (20), 8820-8826, 2013 | 28 | 2013 |
| Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block PN Tran, J Sheng, AL Randolph, CA Baron, N Thiebaud, M Ren, M Wu, ... PLoS One 15 (11), e0241362, 2020 | 21 | 2020 |
| Characterization of loperamide-mediated block of hERG channels at physiological temperature and its proarrhythmia propensity J Sheng, PN Tran, Z Li, S Dutta, K Chang, T Colatsky, WW Wu Journal of Pharmacological and Toxicological Methods 88, 109-122, 2017 | 18 | 2017 |
