Megan L. McCain
Megan L. McCain
Assistant Professor of Biomedical Engineering and Stem Cell Biology & Regenerative Medicine
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ...
Nature medicine 20 (6), 616-623, 2014
A tissue-engineered jellyfish with biomimetic propulsion
JC Nawroth, H Lee, AW Feinberg, CM Ripplinger, ML McCain, ...
Nature biotechnology 30 (8), 792-797, 2012
Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip
A Grosberg, PW Alford, ML McCain, KK Parker
Lab on a chip 11 (24), 4165-4173, 2011
Microfluidic heart on a chip for higher throughput pharmacological studies
A Agarwal, JA Goss, A Cho, ML McCain, KK Parker
Lab on a Chip 13 (18), 3599-3608, 2013
Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function
ML McCain, KK Parker
Pflügers Archiv-European Journal of Physiology 462 (1), 89-104, 2011
Cooperative coupling of cell-matrix and cell–cell adhesions in cardiac muscle
ML McCain, H Lee, Y Aratyn-Schaus, AG Kléber, KK Parker
Proceedings of the National Academy of Sciences 109 (25), 9881-9886, 2012
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues
ML McCain, A Agarwal, HW Nesmith, AP Nesmith, KK Parker
Biomaterials 35 (21), 5462-5471, 2014
Muscle on a chip: in vitro contractility assays for smooth and striated muscle
A Grosberg, AP Nesmith, JA Goss, MD Brigham, ML McCain, KK Parker
Journal of pharmacological and toxicological methods 65 (3), 126-135, 2012
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip
ML McCain, SP Sheehy, A Grosberg, JA Goss, KK Parker
Proceedings of the National Academy of Sciences 110 (24), 9770-9775, 2013
Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction
WJ Hucker, ML Mccain, JI Laughner, PA Iaizzo, IR Efimov
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2008
Micropatterning alginate substrates for in vitro cardiovascular muscle on a chip
A Agarwal, Y Farouz, AP Nesmith, LF Deravi, ML McCain, KK Parker
Advanced functional materials 23 (30), 3738-3746, 2013
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility
ML McCain, H Yuan, FS Pasqualini, PH Campbell, KK Parker
American Journal of Physiology-Heart and Circulatory Physiology 306 (11 …, 2014
Prolonged culture of aligned skeletal myotubes on micromolded gelatin hydrogels
A Bettadapur, GC Suh, NA Geisse, ER Wang, C Hua, HA Huber, ...
Scientific reports 6 (1), 1-14, 2016
Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current
T Desplantez, ML McCain, P Beauchamp, G Rigoli, B Rothen-Rutishauser, ...
Cardiovascular research 94 (1), 58-65, 2012
Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance
ML McCain, T Desplantez, NA Geisse, B Rothen-Rutishauser, H Oberer, ...
American journal of physiology-heart and circulatory physiology 302 (2 …, 2012
Electrical coupling and propagation in engineered ventricular myocardium with heterogeneous expression of connexin43
P Beauchamp, T Desplantez, ML McCain, W Li, A Asimaki, G Rigoli, ...
Circulation research 110 (11), 1445-1453, 2012
Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation
AP Nesmith, A Agarwal, ML McCain, KK Parker
Lab on a chip 14 (20), 3925-3936, 2014
Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment
DM Lyra-Leite, AM Andres, AP Petersen, NR Ariyasinghe, N Cho, JA Lee, ...
American Journal of Physiology-Heart and Circulatory Physiology 313 (4 …, 2017
Tumor-associated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity
A Biragyn, R Schiavo, P Olkhanud, K Sumitomo, A King, M McCain, ...
The Journal of Immunology 179 (2), 1381-1388, 2007
Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy
Y Aratyn-Schaus, FS Pasqualini, H Yuan, ML McCain, GJC Ye, ...
Journal of Cell Biology 212 (4), 389-397, 2016
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