Xin Wang
Xin Wang
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Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351-357, 2016
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of Clinical Oncology 32 (9), 886-896, 2014
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ...
Acta neuropathologica 126 (6), 917-929, 2013
Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells
X Wang, C Venugopal, B Manoranjan, N McFarlane, E O'Farrell, S Nolte, ...
Oncogene 31 (2), 187-199, 2012
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ...
Acta neuropathologica 125 (3), 373-384, 2013
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ...
Nature 553 (7686), 101, 2018
Medulloblastoma subgroup-specific outcomes in irradiated children: who are the true high-risk patients?
V Ramaswamy, M Remke, J Adamski, U Bartels, U Tabori, X Wang, ...
Neuro-oncology 18 (2), 291-297, 2015
Spatial heterogeneity in medulloblastoma
AS Morrissy, FMG Cavalli, M Remke, V Ramaswamy, DJH Shih, ...
Nature Genetics 49 (5), 780-788, 2017
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases
L Garzia, N Kijima, AS Morrissy, P De Antonellis, A Guerreiro-Stucklin, ...
Cell 172 (5), 1050-1062. e14, 2018
Medulloblastoma subgroups remain stable across primary and metastatic compartments
X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ...
Acta neuropathologica 129 (3), 449-457, 2015
FoxG1 Interacts with Bmi1 to Regulate Self‐Renewal and Tumorigenicity of Medulloblastoma Stem Cells
B Manoranjan, X Wang, RM Hallett, C Venugopal, SC Mack, N McFarlane, ...
Stem Cells 31 (7), 1266-1277, 2013
Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma
CC Faria, BJ Golbourn, AM Dubuc, M Remke, RJ Diaz, S Agnihotri, ...
Cancer research, 2014
Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells
C Venugopal, N Li, X Wang, B Manoranjan, C Hawkins, T Gunnarsson, ...
Stem cell research 8 (2), 141-153, 2012
Duration of the pre‐diagnostic interval in medulloblastoma is subgroup dependent
V Ramaswamy, M Remke, D Shih, X Wang, PA Northcott, CC Faria, ...
Pediatric blood & cancer 61 (7), 1190-1194, 2014
Deconstruction of medulloblastoma cellular heterogeneity reveals differences between the most highly invasive and self-renewing phenotypes
LC Morrison, R McClelland, C Aiken, M Bridges, L Liang, X Wang, ...
Neoplasia 15 (4), 384IN6-398IN8, 2013
Spinal myxopapillary ependymomas demonstrate a warburg phenotype
SC Mack, S Agnihotri, KC Bertrand, X Wang, DJ Shih, H Witt, N Hill, ...
Clinical Cancer Research 21 (16), 3750-3758, 2015
Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis
IS Shimada, SH Hwang, BN Somatilaka, X Wang, P Skowron, J Kim, ...
Cell reports 22 (5), 1169-1184, 2018
The Rising Challenge of Training Physician–scientists: Recommendations From a Canadian National Consensus Conference
MJ Strong, N Busing, DL Goosney, KA Harris, T Horsley, A Kuzyk, ...
Academic Medicine, 2017
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